27453-1-AP

antibody from Proteintech Group

Targeting: CACNA2D1 CACNA2, CACNL2A, LINC01112, lncRNA-N3, MHS3

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

27453-1-AP

Provider

Proteintech Group

Product name

CACNA2D1 antibody

Antibody type

Polyclonal

Description

CACNA2D1 antibody (Cat. #27453-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, pig, rat and has been validated for the following applications: IHC, WB,ELISA.

Reactivity

Human, Mouse, Rat, Porcine

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

The ER membrane protein complex acts as a chaperone to promote the biogenesis of multi-bundle membrane proteins.

Stanton M, Singal B, Biswal M, Agarwal M, Scheuing CE, Vargas GD, Gao A, Gifford CA, Pleiner T
bioRxiv : the preprint server for biology 2026 Jan 15;

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Fuling Wenxin formula treats "Qi-Yin deficiency" arrhythmia by regulating the dilated cardiomyopathy and adrenergic signaling pathway in cardiomyocytes.

Yang SR, Tang ZS, Liu YR, Song ZX, Wang MG
Phytomedicine : international journal of phytotherapy and phytopharmacology 2025 Jul;142:156812

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Pathophysiology-Directed Engineering of a Combination Nanoanalgesic for Neuropathic Pain.

Wang W, Wang Y, Huang X, Wu P, Li L, Zhang Y, Chen Y, Chen Z, Li C, Zhou Y, Zhang J
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Feb;12(8):e2405483

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Scavenger Receptor Class B Type I Modulates Epileptic Seizures and Receptor α2δ-1 Expression.

Huang Y, Gao Y, Huang Z, Liang M, Chen Y
Neurochemical research 2024 Oct;49(10):2842-2853

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ChIP-seq and RNA-seq Reveal the Involvement of Histone Lactylation Modification in Gestational Diabetes Mellitus.

Huang X, Yip K, Nie H, Chen R, Wang X, Wang Y, Lin W, Li R
Journal of proteome research 2024 Jun 7;23(6):1937-1947

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CACNA2D1 regulates the progression and influences the microenvironment of colon cancer.

Inoue H, Shiozaki A, Kosuga T, Shimizu H, Kudou M, Arita T, Konishi H, Komatsu S, Kuriu Y, Kubota T, Fujiwara H, Morinaga Y, Konishi E, Otsuji E
Journal of gastroenterology 2024 Jul;59(7):556-571

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Exercise training affects calcium ion transport by downregulating the CACNA2D1 protein to reduce hypertension-induced myocardial injury in mice.

Gao S, Yao W, Zhou R, Pei Z
iScience 2024 Apr 19;27(4):109351

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Cherry leaf decoction inhibits NMDAR expression and thereby ameliorates CUMS- induced depression-like behaviors through downregulation of α2δ-1.

Jiang C, Wang C, Qu W, Wang Y, Wang H, Wei X, Wang M, He Q, Wang Y, Yuan L, Gao Y
Heliyon 2023 Nov;9(11):e21743

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Cigarette smoke triggers calcium overload in mouse hippocampal neurons via the ΔFOSB-CACNA2D1 axis to impair cognitive performance.

Zhang H, Zhou H, Guo X, Zhang G, Xiao M, Wu S, Jin C, Yang J, Lu X
Ecotoxicology and environmental safety 2023 Jun 15;258:114996

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Calcium-Related Genes Predicting Outcomes and Serving as Therapeutic Targets in Endometrial Cancer.

Huang T, Feng X, Wang J, Zhou J, Wang J
Cells 2022 Oct 8;11(19)

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Microglial IL-10 and β-endorphin expression mediates gabapentinoids antineuropathic pain.

Ahmad KA, Shoaib RM, Ahsan MZ, Deng MY, Ma L, Apryani E, Li XY, Wang YX
Brain, behavior, and immunity 2021 Jul;95:344-361