PA5-60882

antibody from Invitrogen Antibodies

Targeting: RNASE2 EDN, RAF3, RNS2

Immunohistochemistry (Data presented on provider website)

Other assay (Supportive data in Antibodypedia)

Antibody Data

Product number

PA5-60882

Provider

Invitrogen Antibodies

Product name

RNASE2 Polyclonal Antibody

Antibody type

Polyclonal

Antigen

Recombinant full-length protein

Description

Immunogen sequence: QFTWAQWFET QHINMTSQQC TNAMQV Highest antigen sequence identity to the following orthologs: Mouse - 44%, Rat - 46%.

Reactivity

Human

Host

Rabbit

Isotype

IgG

Vial size

100 µL

Concentration

0.08 mg/mL

Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

References

Submitted references

An Increasing Trend of Eosinophilic Esophagitis in Korea and the Clinical Implication of the Biomarkers to Determine Disease Activity and Treatment Response in Eosinophilic Esophagitis.

Kim GH, Park YS, Jung KW, Kim M, Na HK, Ahn JY, Lee JH, Kim DH, Choi KD, Song HJ, Lee GH, Dellon ES, Jung HY
Journal of neurogastroenterology and motility 2019 Oct 30;25(4):525-533

Other assay

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Figure 3 Histologic findings before and after treatment in a patient with eosinophilic esophagitis (EoE). (A) Hematoxylin and eosin staining shows an elevated eosinophil counts (x400) and normalization after therapy (x400). (B) The tryptase staining shows elevated number of stained cells and normalization after therapy (x400). (C) The eosinophil-derived neurotoxin staining shows an elevated number of stained cells (x400) and normalization after therapy (x400). (D) Eotaxin-3 staining shows elevated number of stained cells (x400) and normalization after therapy (x400).