PA5-97305

antibody from Invitrogen Antibodies

Targeting: RNASE2 EDN, RAF3, RNS2

Western blot (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

PA5-97305

Provider

Invitrogen Antibodies

Product name

RNASE2 Polyclonal Antibody

Antibody type

Polyclonal

Antigen

Recombinant full-length protein

Description

Immunogen sequence: KPPQFTWAQW FETQHINMTS QQCTNAMQVI NNYQRRCKNQ NTFLLTTFAN VVNVCGNPNM TCPSNKTRKN CHHSGSQVPL IHCNLTTPSP QNISNCRYAQ TPANMFYIVA CDNRDQRRDP PQYPVVPVHL DRII; Positive Samples: K-562, HL-60, Mouse liver; Cellular Location: Cytoplasmic granule, Lysosome

Reactivity

Human, Mouse

Host

Rabbit

Isotype

IgG

Vial size

100 µL

Concentration

0.52 mg/mL

Storage

-20° C, Avoid Freeze/Thaw Cycles

References

Submitted references

Immune Sensing of Synthetic, Bacterial, and Protozoan RNA by Toll-like Receptor 8 Requires Coordinated Processing by RNase T2 and RNase 2.

Ostendorf T, Zillinger T, Andryka K, Schlee-Guimaraes TM, Schmitz S, Marx S, Bayrak K, Linke R, Salgert S, Wegner J, Grasser T, Bauersachs S, Soltesz L, Hübner MP, Nastaly M, Coch C, Kettwig M, Roehl I, Henneke M, Hoerauf A, Barchet W, Gärtner J, Schlee M, Hartmann G, Bartok E
Immunity 2020 Apr 14;52(4):591-605.e6

Immunohistochemistry

Supportive validation

Submitted by

Invitrogen Antibodies (provider)

Main image

Experimental details

Immunohistochemistry (Immunofluorescence) analysis of RNASE2 in mouse spleen. Samples were incubated with RNASE2 Polyclonal antibody (Product # PA5-97305) using a dilution of 1:100 (40x lens). Blue: DAPI for nuclear staining.