18030-1-AP
antibody from Proteintech Group
Targeting: TNKS
ARTD5, PARP-5a, PARP5A, pART5, TIN1, TINF1, TNKS1
Antibody data
- Antibody Data
- Antigen structure
- References [11]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- 18030-1-AP - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#18030-1-AP, RRID:AB_2303564
- Product name
- TNKS antibody
- Antibody type
- Polyclonal
- Description
- TNKS antibody (Cat. #18030-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Very long-chain fatty acids control peroxisome dynamics via a feedback loop in intestinal stem cells during gut regeneration.
The dePARylase NUDT16 promotes radiation resistance of cancer cells by blocking SETD3 for degradation via reversing its ADP-ribosylation.
PARP5A and RNF146 phase separation restrains RIPK1-dependent necroptosis.
Study of the mechanism by which Xiaoyan decoction combined with E7449 regulates tumorigenesis in lung adenocarcinoma.
Minimizing DNA trapping while maintaining activity inhibition via selective PARP1 degrader.
Identification and evaluation of a novel PARP1 inhibitor for the treatment of triple-negative breast cancer.
Iron promotes glycolysis to drive colon tumorigenesis.
Transferrin Receptor-Mediated Iron Uptake Promotes Colon Tumorigenesis.
Knockout of syntaxin-4 in 3T3-L1 adipocytes reveals new insight into GLUT4 trafficking and adiponectin secretion.
Dihydroartemisinin suppresses proliferation, migration, the Wnt/β-catenin pathway and EMT via TNKS in gastric cancer.
circ5615 functions as a ceRNA to promote colorectal cancer progression by upregulating TNKS.
Guo X, Zhou J, La Yan, Liu X, Yuan Y, Ye J, Zhang Z, Chen H, Ma Y, Zhong Z, Luo G, Chen H
Developmental cell 2024 Nov 18;59(22):3008-3024.e8
Developmental cell 2024 Nov 18;59(22):3008-3024.e8
The dePARylase NUDT16 promotes radiation resistance of cancer cells by blocking SETD3 for degradation via reversing its ADP-ribosylation.
Wu W, Wu W, Zhou Y, Yang Q, Zhuang S, Zhong C, Li W, Li A, Zhao W, Yin X, Zu X, Chak-Lui Wong C, Yin D, Hu K, Cai M
The Journal of biological chemistry 2024 Mar;300(3):105671
The Journal of biological chemistry 2024 Mar;300(3):105671
PARP5A and RNF146 phase separation restrains RIPK1-dependent necroptosis.
Hou S, Zhang J, Jiang X, Yang Y, Shan B, Zhang M, Liu C, Yuan J, Xu D
Molecular cell 2024 Mar 7;84(5):938-954.e8
Molecular cell 2024 Mar 7;84(5):938-954.e8
Study of the mechanism by which Xiaoyan decoction combined with E7449 regulates tumorigenesis in lung adenocarcinoma.
Zheng X, Han Y, Gu L, Gao S, Lv Y, Li C
Journal of cellular and molecular medicine 2024 Jun;28(12):e18467
Journal of cellular and molecular medicine 2024 Jun;28(12):e18467
Minimizing DNA trapping while maintaining activity inhibition via selective PARP1 degrader.
Chen L, Zou Y, Sun R, Huang M, Zhu X, Tang X, Yang X, Li D, Fan G, Wang Y
Cell death & disease 2024 Dec 18;15(12):898
Cell death & disease 2024 Dec 18;15(12):898
Identification and evaluation of a novel PARP1 inhibitor for the treatment of triple-negative breast cancer.
Gong R, Ma Z, He L, Jiang S, Cao D, Cheng Y
Chemico-biological interactions 2023 Sep 1;382:110567
Chemico-biological interactions 2023 Sep 1;382:110567
Iron promotes glycolysis to drive colon tumorigenesis.
Liu Z, Villareal L, Goodla L, Kim H, Falcon DM, Haneef M, Martin DR, Zhang L, Lee HJ, Kremer D, Lyssiotis CA, Shah YM, Lin HC, Lin HK, Xue X
Biochimica et biophysica acta. Molecular basis of disease 2023 Dec;1869(8):166846
Biochimica et biophysica acta. Molecular basis of disease 2023 Dec;1869(8):166846
Transferrin Receptor-Mediated Iron Uptake Promotes Colon Tumorigenesis.
Kim H, Villareal LB, Liu Z, Haneef M, Falcon DM, Martin DR, Lee HJ, Dame MK, Attili D, Chen Y, Varani J, Spence JR, Kovbasnjuk O, Colacino JA, Lyssiotis CA, Lin HC, Shah YM, Xue X
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Apr;10(10):e2207693
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2023 Apr;10(10):e2207693
Knockout of syntaxin-4 in 3T3-L1 adipocytes reveals new insight into GLUT4 trafficking and adiponectin secretion.
Black HL, Livingstone R, Mastick CC, Al Tobi M, Taylor H, Geiser A, Stirrat L, Kioumourtzoglou D, Petrie JR, Boyle JG, Bryant NJ, Gould GW
Journal of cell science 2022 Dec 1;135(1)
Journal of cell science 2022 Dec 1;135(1)
Dihydroartemisinin suppresses proliferation, migration, the Wnt/β-catenin pathway and EMT via TNKS in gastric cancer.
Ma Y, Zhang P, Zhang Q, Wang X, Miao Q, Lyu X, Cui B, Ma H
Oncology letters 2021 Oct;22(4):688
Oncology letters 2021 Oct;22(4):688
circ5615 functions as a ceRNA to promote colorectal cancer progression by upregulating TNKS.
Ma Z, Han C, Xia W, Wang S, Li X, Fang P, Yin R, Xu L, Yang L
Cell death & disease 2020 May 11;11(5):356
Cell death & disease 2020 May 11;11(5):356
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 18030-1-AP(TNKS antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunofluorescent analysis of HepG2 cells, using TNKS antibody 18030-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line