21774-1-AP

antibody from Proteintech Group

Targeting: CACNA1C CACH2, CACN2, CACNL1A1, Cav1.2, CCHL1A1, LQT8, TS

Provider product page for 21774-1-AP

ELISA

Immunocytochemistry

Immunohistochemistry

Antibody data

Antibody Data
Antigen structure
References [23]
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Product number: 21774-1-AP - Provider product page
Provider: Proteintech Group
Product name: L-VOCC antibody
Antibody type: Polyclonal
Description: L-VOCC antibody (Cat. #21774-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC,ELISA.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Isotype: IgG
Vial size: 20ul, 150ul

CACNA1C protein structure - 21774-1-AP shown in red.

Submitted references Development and clinical validation of a seven-gene signature based on tumor stem cell-related genes to predict ovarian cancer prognosis.

Wang G, Liu X, You Y, Chen S, Chang X, Yang Q
Journal of ovarian research 2024 Mar 13;17(1):58

Anji white tea relaxes precontracted arteries, represses voltage-gated Ca(2+) channels and voltage-gated K(+) channels in the arterial smooth muscle cells: Comparison with green tea main component (-)-epigallocatechin gallate.

Xu X, Fan Y, Yang X, Liu Y, Wang Y, Zhang J, Hou X, Fan Y, Zhang M
Journal of ethnopharmacology 2024 Jun 28;328:117855

Patient-specific iPSC-derived cardiomyocytes reveal variable phenotypic severity of Brugada syndrome.

Sun Y, Su J, Wang X, Wang J, Guo F, Qiu H, Fan H, Cai D, Wang H, Lin M, Wang W, Feng Y, Fu G, Gong T, Liang P, Jiang C
EBioMedicine 2023 Sep;95:104741

Berberine attenuates sunitinib-induced cardiac dysfunction by normalizing calcium regulation disorder via SGK1 activation.

Li C, Wu W, Xing J, Yan W, Zhang J, Sun J, Zhang Z, Qiu S, Xu Y, Wang X
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2023 May;175:113743

In vitro fertilization with frozen embryo transfer increased histamine-mediated contractile sensitivity via PKCβ in human umbilical vein.

Tang J, Qi L, He Y, Li N, Zhang Z, Zhou X, Su H, Zheng Q, Zhang Y, Tao J, Xu Z
Reproductive biology and endocrinology : RB&E 2023 Jun 13;21(1):54

Perinatal Fat-Diets Increased Angiotensin II-Mediated Ca(2+) through PKC-L-Type Calcium Channel Axis in Resistance Arteries via Agtr1a-Prkcb Gene Methylation.

Zheng Q, He Y, Li L, Rui C, Li N, Zhang Y, Ye Y, Zhang Z, Yang X, Tang J, Xu Z
Nutrients 2023 Jan 3;15(1)

Pinocembrin attenuates susceptibility to atrial fibrillation in rats with pulmonary arterial hypertension.

Yi Y, Tianxin Y, Zhangchi L, Cui Z, Weiguo W, Bo Y
European journal of pharmacology 2023 Dec 5;960:176169

Chronic Administration of COVID-19 Drugs Fluvoxamine and Lopinavir Shortens Action Potential Duration by Inhibiting the Human Ether-à-go-go-Related Gene and Cav1.2.

Zheng Z, Cai D, Fu Y, Wang Y, Song Y, Lian J
Frontiers in pharmacology 2022;13:889713

Cytosolic peptides encoding Ca(V)1 C-termini downregulate the calcium channel activity-neuritogenesis coupling.

Yang Y, Yu Z, Geng J, Liu M, Liu N, Li P, Hong W, Yue S, Jiang H, Ge H, Qian F, Xiong W, Wang P, Song S, Li X, Fan Y, Liu X
Communications biology 2022 May 19;5(1):484

Calcium released by osteoclastic resorption stimulates autocrine/paracrine activities in local osteogenic cells to promote coupled bone formation.

Ahmed ASI, Sheng MHC, Lau KW, Wilson SM, Wongworawat MD, Tang X, Ghahramanpouri M, Nehme A, Xu Y, Abdipour A, Zhang XB, Wasnik S, Baylink DJ
American journal of physiology. Cell physiology 2022 May 1;322(5):C977-C990

Anthracycline-Induced Atrial Structural and Electrical Remodeling Characterizes Early Cardiotoxicity and Contributes to Atrial Conductive Instability and Dysfunction.

Tan R, Cong T, Xu G, Hao Z, Liao J, Xie Y, Lin Y, Yang X, Li Q, Liu Y, Xia YL
Antioxidants & redox signaling 2022 Jul;37(1-3):19-39

Pinocembrin alleviates the susceptibility to atrial fibrillation in isoproterenol-induced rats.

Liu Z, Chen X, Ye T, Wan W, Yu Y, Zhang C, Yang B
Biochemical and biophysical research communications 2022 Dec 25;636(Pt 1):33-40

Harm of circadian misalignment to the hearts of the adolescent wistar rats.

Wang Y, Hou Y, Song S, Zuo Y, Yu Y, Chi Y, Zhang T
Journal of translational medicine 2022 Aug 6;20(1):352

Pinocembrin mediates antiarrhythmic eﬀects in rats with isoproterenol-induced cardiac remodeling.

Chen X, Wan W, Ran Q, Ye T, Sun Y, Liu Z, Liu X, Shi S, Qu C, Zhang C, Yang B
European journal of pharmacology 2022 Apr 5;920:174799

Methylation-reprogrammed CHRM3 results in vascular dysfunction in the human umbilical vein following IVF-ET†.

Shi Y, Liu J, Zhu D, Lu L, Zhang M, Li W, Zeng H, Yu X, Guo J, Zhang Y, Zhou X, Gao Q, Xia F, Chen Y, Li M, Sun M
Biology of reproduction 2022 Apr 26;106(4):687-698

Exosomal miR-29b found in aqueous humour mediates calcium signaling in diabetic patients with cataract.

Gao C, Liu X, Fan F, Yang JN, Zhou XY, Mei HJ, Lin XL, Luo Y
International journal of ophthalmology 2021;14(10):1484-1491

Interleukin-6-Mediated-Ca(2+) Handling Abnormalities Contributes to Atrial Fibrillation in Sterile Pericarditis Rats.

Liao J, Zhang S, Yang S, Lu Y, Lu K, Wu Y, Wu Q, Zhao N, Dong Q, Chen L, Du Y
Frontiers in immunology 2021;12:758157

Evidence of Ventricular Arrhythmogenicity and Cardiac Sympathetic Hyperinnervation in Early Cirrhotic Cardiomyopathy.

Liu SH, Lo LW, Chou YH, Lin WL, Tsai TY, Cheng WH, Lin YJ, Chang SL, Hu YF, Chung FP, Huang HC, Chen SA
Frontiers in physiology 2021;12:719883

Effects of Angiotensin Receptor-Neprilysin Inhibitor in Arrhythmogenicity Following Left Atrial Appendage Closure in an Animal Model.

Cheng WH, Lugtu IC, Chang SL, Liu SH, Chen SA, Lo LW
Cardiovascular drugs and therapy 2021 Aug;35(4):759-768

Prenatal hypoxia attenuated contraction of offspring coronary artery associated with decreased PKCβ Ser(660) phosphorylation and intracellular calcium.

Chen X, Qi L, Su H, He Y, Li N, Gao Q, Li H, Xu T, Lu L, Xu Z, Tang J
Life sciences 2020 Nov 15;261:118364

In utero hypoxia altered Ang II-induced contraction via PKCβ in fetal cerebral arteries.

Su H, Chen X, Zhang Y, Qi L, He Y, Lv J, Zhang Y, Li X, Tang J, Xu Z
The Journal of endocrinology 2020 Jan;244(1):213-222

Quercetin Attenuates Ethanol-Induced Iron Uptake and Myocardial Injury by Regulating the Angiotensin II-L-Type Calcium Channel.

Guo X, Chen M, Zeng H, Liu P, Zhu X, Zhou F, Liu J, Zhang J, Dong Z, Tang Y, Gao C, Yao P
Molecular nutrition & food research 2018 Mar;62(5)

Protective role and mechanism of snakegourd peel against myocardial infarction in rats.

Yang G, Min D, Yan J, Yang M, Lin G
Phytomedicine : international journal of phytotherapy and phytopharmacology 2018 Mar 15;42:18-24

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