10864-2-AP

antibody from Proteintech Group

Targeting: GM2A SAP-3

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

10864-2-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#10864-2-AP, RRID:AB_2110807

Product name

GM2A antibody

Antibody type

Polyclonal

Description

KD/KO validated GM2A antibody (Cat. #10864-2-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Elevated ganglioside GM2 activator (GM2A) in human brain tissue reduces neurite integrity and spontaneous neuronal activity.

Hsieh YC, Negri J, He A, Pearse RV 2nd, Liu L, Duong DM, Chibnik LB, Bennett DA, Seyfried NT, Young-Pearse TL
Molecular neurodegeneration 2022 Sep 21;17(1):61

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Deficiency of the frontotemporal dementia gene GRN results in gangliosidosis.

Boland S, Swarup S, Ambaw YA, Malia PC, Richards RC, Fischer AW, Singh S, Aggarwal G, Spina S, Nana AL, Grinberg LT, Seeley WW, Surma MA, Klose C, Paulo JA, Nguyen AD, Harper JW, Walther TC, Farese RV Jr
Nature communications 2022 Oct 7;13(1):5924

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Glycosphingolipid GM2 Induces Invasiveness in Irradiation-tolerant Lung Cancer Cells.

Ishihara S, Aoki K, Mizutani T, Amano M, Nishimura SI, Haga H
Cell structure and function 2018;43(2):177-185

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Expression and regulation of type 2A protein phosphatases and alpha4 signalling in cardiac health and hypertrophy.

Eleftheriadou O, Boguslavskyi A, Longman MR, Cowan J, Francois A, Heads RJ, Wadzinski BE, Ryan A, Shattock MJ, Snabaitis AK
Basic research in cardiology 2017 Jul;112(4):37