BS2174

antibody from Bioworld Technology, Inc
Targeting: SUPT16H CDC68, FACT, FACTP140, FLJ10857, FLJ14010, SPT16/CDC68
Provider product page for BS2174
Western blot
Immunohistochemistry

Antibody data

Product number
BS2174 - Provider product page
Provider
Bioworld Technology, Inc
Product name
SPT16 (S967) polyclonal antibody
Antibody type
Polyclonal
Antigen
Synthetic peptide, corresponding to amino acids 932-977 of Human SPT16.
Description
FACT is a chromatin-specific elongation factor required for transcription of chromatin templates, and it specifically interacts with nucleosomes and histone H2A/H2B dimers, to promote nucleosome disassembly upon transcription. FACT represents a complex between SPT16, a homologue of the Saccharomyces cerevisiae Spt16/Cdc68 protein, and the high-mobility group (HMG)-1-like protein structure-specific recognition protein-1 (SSRP-1). Similar to other (HMG) domain containing proteins, which are characterized by their ability to bend target DNAs, SSRP1 and the murine ortholog T160, physically interact with serum response factors (SRF) and function as a positive co regulatory proteins involved in modulating SRF-dependent gene expression.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
SUPT16H protein structure - BS2174 shown in red.