CABT-B11564

antibody from Creative Diagnostics

Targeting: SUPT16H CDC68, FACT, FACTP140, FLJ10857, FLJ14010, SPT16/CDC68

No application information provided.

Antibody Data

Product number

CABT-B11564

Provider

Creative Diagnostics

Product name

Mouse anti-Human SUPT16H monoclonal antibody, clone 9E3

Antibody type

Monoclonal

Description

Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit