26143-1-AP

antibody from Proteintech Group

Targeting: USP17L2 DUB3

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

26143-1-AP

Provider

Proteintech Group

Product name

DUB3 antibody

Antibody type

Polyclonal

Description

DUB3 antibody (Cat. #26143-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: WB,ELISA.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Targeting CDK4/6 suppresses colorectal cancer by destabilizing YAP1.

Wen Y, Yang X, Li S, Huang L, Chen J, Tan L, Ma X, Zhu Y, Li Z, Shan C, Zhang C, Zhang Q, Liang M, Zhang H, Liu T
MedComm 2025 Mar;6(3):e70103

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Redox-Induced Stabilization of AMBRA1 by USP7 Promotes Intestinal Oxidative Stress and Colitis Through Antagonizing DUB3-Mediated NRF2 Deubiquitination.

Xu W, Hua Z, Wang Y, Tang W, Ge W, Chen Y, Wang Z, Gu Y, Liu CY, Du P
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Mar;12(12):e2411320

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CK2α-mediated phosphorylation of DUB3 promotes YAP1 stability and oncogenic functions.

Huang L, Wen Y, Guo Q, Zhang C, Yang X, Li M, Liu Y, Li X, Tang J, Zhou X, Qi Q, Zhang H, Liu T
Cell death & disease 2025 Jan 18;16(1):27

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CDK4/6-mediated phosphorylation of DUB3 promotes YAP1 stability and hepatocellular carcinoma progression.

Huang L, Yuan W, Li X, Liu Y, Wan R, Ma X, Liu T, Liang J, Zhu Y
Cell death discovery 2025 Apr 30;11(1):212

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DUB3 is a MAGEA3 deubiquitinase and a potential therapeutic target in hepatocellular carcinoma.

Chen Y, Gao F, He Y, Liu M, Quan Y, Zhang P
iScience 2024 Mar 15;27(3):109181

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NFATc2 promotes lactate and M2 macrophage polarization through USP17 in lung adenocarcinoma.

Wang L, Ma Y, Zhang S, Yang Y, Huang B
Anti-cancer drugs 2024 Jun 1;35(5):385-396

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Melatonin alleviates hyperoxia-induced lung injury through elevating MSC exosomal miR-18a-5p expression to repress PUM2 signaling.

Zou D, Liao J, Xiao M, Liu L, Xu M
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2024 Aug 31;38(16):e70012

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C4orf19 inhibits colorectal cancer cell proliferation by competitively binding to Keap1 with TRIM25 via the USP17/Elk-1/CDK6 axis.

Huang S, Li J, Wu S, Zheng Z, Wang C, Li H, Zhao L, Zhang X, Huang H, Huang C, Xie Q
Oncogene 2023 Apr;42(17):1333-1346

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Sarmentosin promotes USP17 and regulates Nrf2-mediated mitophagy and cellular oxidative stress to alleviate APAP-induced acute liver failure.

Jiang Z, Yang X, Han Y, Li J, Hu C, Liu C, Xiao W
Phytomedicine : international journal of phytotherapy and phytopharmacology 2022 Sep;104:154337

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USP17L2-SIRT7 axis regulates DNA damage repair and chemoresistance in breast cancer cells.

Su Y, Wu C, Chang Y, Li L, Chen Y, Jia X, Wang X, Lv Y, Yu B, Yuan J
Breast cancer research and treatment 2022 Nov;196(1):31-44

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Lysophosphatidic Acid-Induced EGFR Transactivation Promotes Gastric Cancer Cell DNA Replication by Stabilizing Geminin in the S Phase.

Zhao H, Gezi G, Tian X, Jia P, Morigen M, Fan L
Frontiers in pharmacology 2021;12:706240