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ELISAAntibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 60316-1-Ig - Provider product page
- Provider
- Proteintech Group
- Product name
- VCP antibody
- Antibody type
- Monoclonal
- Description
- KD/KO validated VCP antibody (Cat. #60316-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 2A4B10
- Vial size
- 20ul, 150ul
Submitted references RNA damage compartmentalization by DHX9 stress granules.
SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.
GLI1, a novel target of the ER stress regulator p97/VCP, promotes ATF6f-mediated activation of XBP1.
Interactome screening of C9orf72 dipeptide repeats reveals VCP sequestration and functional impairment by polyGA.
Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex.
Zhou Y, Panhale A, Shvedunova M, Balan M, Gomez-Auli A, Holz H, Seyfferth J, Helmstädter M, Kayser S, Zhao Y, Erdogdu NU, Grzadzielewska I, Mittler G, Manke T, Akhtar A
Cell 2024 Mar 28;187(7):1701-1718.e28
Cell 2024 Mar 28;187(7):1701-1718.e28
SERBP1 Promotes Stress Granule Clearance by Regulating 26S Proteasome Activity and G3BP1 Ubiquitination and Protects Male Germ Cells from Thermostimuli Damage.
Wang F, Wang L, Gan S, Feng S, Ouyang S, Wang X, Yuan S
Research (Washington, D.C.) 2023;6:0091
Research (Washington, D.C.) 2023;6:0091
GLI1, a novel target of the ER stress regulator p97/VCP, promotes ATF6f-mediated activation of XBP1.
Almada LL, Barroso K, Sen S, Toruner M, Sigafoos AN, Raja Arul GL, Pease DR, Vera RE, Olson RLO, Auner HW, Pedeux R, Iovanna JL, Chevet E, Fernandez-Zapico ME
Biochimica et biophysica acta. Gene regulatory mechanisms 2023 Jun;1866(2):194924
Biochimica et biophysica acta. Gene regulatory mechanisms 2023 Jun;1866(2):194924
Interactome screening of C9orf72 dipeptide repeats reveals VCP sequestration and functional impairment by polyGA.
Božič J, Motaln H, Janež AP, Markič L, Tripathi P, Yamoah A, Aronica E, Lee YB, Heilig R, Fischer R, Thompson AJ, Goswami A, Rogelj B
Brain : a journal of neurology 2022 Apr 18;145(2):684-699
Brain : a journal of neurology 2022 Apr 18;145(2):684-699
Gossypol, a novel modulator of VCP, induces autophagic degradation of mutant huntingtin by promoting the formation of VCP/p97-LC3-mHTT complex.
Li XJ, Zhang YY, Fu YH, Zhang H, Li HX, Li QF, Li HL, Tan RK, Jiang CX, Jiang W, Li ZX, Luo C, Lu BX, Dang YJ
Acta pharmacologica Sinica 2021 Oct;42(10):1556-1566
Acta pharmacologica Sinica 2021 Oct;42(10):1556-1566
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- RAW 264.7 cells were subjected to SDS PAGE followed by western blot with 60316-1-Ig( VCP Antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The VCP antibody from Proteintech is a mouse monoclonal antibody to a recombinant protein of human VCP. This antibody recognizes human, mouse antigen. The VCP antibody has been validated for the following applications: ELISA, WB, IHC analysis.
