Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations [0]
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- Product number
- ABIN1673606 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Valosin Containing Protein (vcp) (C-Term) antibody
- Antibody type
- Polyclonal
- Antigen
- A synthetic peptide corresponding to a sequence at the C-terminal of human VCP, identical to the related rat and mouse sequences.Immunogen affinity purified.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Epitope
- C-Term
- Isotype
- IgG
- Vial size
- 100 μg
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Patients with a phenotype consistent with facioscapulohumeral muscular dystrophy display genetic and epigenetic heterogeneity.
Transgenic mice expressing mutant forms VCP/p97 recapitulate the full spectrum of IBMPFD including degeneration in muscle, brain and bone.
SEL1L nucleates a protein complex required for dislocation of misfolded glycoproteins.
Inclusion body myopathy and Paget disease is linked to a novel mutation in the VCP gene.
Sacconi S, CamaƱo P, de Greef JC, Lemmers RJ, Salviati L, Boileau P, Lopez de Munain Arregui A, van der Maarel SM, Desnuelle C
Journal of medical genetics 2012 Jan;49(1):41-6
Journal of medical genetics 2012 Jan;49(1):41-6
Transgenic mice expressing mutant forms VCP/p97 recapitulate the full spectrum of IBMPFD including degeneration in muscle, brain and bone.
Custer SK, Neumann M, Lu H, Wright AC, Taylor JP
Human molecular genetics 2010 May 1;19(9):1741-55
Human molecular genetics 2010 May 1;19(9):1741-55
SEL1L nucleates a protein complex required for dislocation of misfolded glycoproteins.
Mueller B, Klemm EJ, Spooner E, Claessen JH, Ploegh HL
Proceedings of the National Academy of Sciences of the United States of America 2008 Aug 26;105(34):12325-30
Proceedings of the National Academy of Sciences of the United States of America 2008 Aug 26;105(34):12325-30
Inclusion body myopathy and Paget disease is linked to a novel mutation in the VCP gene.
Haubenberger D, Bittner RE, Rauch-Shorny S, Zimprich F, Mannhalter C, Wagner L, Mineva I, Vass K, Auff E, Zimprich A
Neurology 2005 Oct 25;65(8):1304-5
Neurology 2005 Oct 25;65(8):1304-5
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