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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [3]
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- Validations
- Flow cytometry [1]
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- Product number
- 12-0793-42 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- CD79b Monoclonal Antibody (CB3-1), PE, eBioscience™
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- Description: This CB3-1 monoclonal antibody reacts with human CD79b, the B cell antigen receptor Ig-beta chain. Together with the Ig alpha chain, also known as CD79a, this cell surface molecule forms a heterodimeric complex that associates with membrane immunoglobulin (mIgM). CD79b expression is exclusive to B lymphocytes and B cell lymphomas. Depending on the maturation state of the B cell, CD79b can be expressed either in the cytoplasm or on the cell surface. The CD79 receptor complex triggers numerous signaling pathways to mediate B cell development, maintenance, and activation.
- Conjugate
- Yellow dye
- Antibody clone number
- CB3-1
- Concentration
- 5 µL/Test
Submitted references Spontaneous production of immunoglobulin M in human epithelial cancer cells.
Differential expression of B29 (CD79b) and mb-1 (CD79a) proteins in acute lymphoblastic leukaemia.
Heterogeneity of immunoglobulin-associated molecules on human B cells identified by monoclonal antibodies.
Hu F, Zhang L, Zheng J, Zhao L, Huang J, Shao W, Liao Q, Ma T, Geng L, Yin CC, Qiu X
PloS one 2012;7(12):e51423
PloS one 2012;7(12):e51423
Differential expression of B29 (CD79b) and mb-1 (CD79a) proteins in acute lymphoblastic leukaemia.
Astsaturov IA, Matutes E, Morilla R, Seon BK, Mason DY, Farahat N, Catovsky D
Leukemia 1996 May;10(5):769-73
Leukemia 1996 May;10(5):769-73
Heterogeneity of immunoglobulin-associated molecules on human B cells identified by monoclonal antibodies.
Nakamura T, Kubagawa H, Cooper MD
Proceedings of the National Academy of Sciences of the United States of America 1992 Sep 15;89(18):8522-6
Proceedings of the National Academy of Sciences of the United States of America 1992 Sep 15;89(18):8522-6
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Supportive validation
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- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- Staining of normal human peripheral blood cells with Anti-Human CD19 APC (Product # 17-0199-42) and Mouse IgG1 K Isotype Control PE (Product # 12-4714-81) (left) or Anti-Human CD79b PE (right). Cells in the lymphocyte gate were used for analysis.
- Conjugate
- Yellow dye
