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Flow cytometryAntibody data
- Antibody Data
- Antigen structure
- References [2]
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- Validations
- Flow cytometry [1]
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- Product number
- 14-0793-82 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- CD79b Monoclonal Antibody (CB3-1), eBioscience™
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- Description: This CB3-1 monoclonal antibody reacts with human CD79b, the B cell antigen receptor Ig-beta chain. Together with the Ig-alpha chain, also known as CD79a, this cell surface molecule forms a heterodimeric complex that associates with membrane immunoglobulin (mIgM). CD79b expression is exclusive to B lymphocytes and B cell lymphomas. Depending on the maturation state of the B cell, CD79b can be expressed either in the cytoplasm or on the cell surface. The CD79 receptor complex triggers numerous signaling pathways to mediate B cell development, maintenance, and activation.
- Antibody clone number
- CB3-1
- Concentration
- 0.5 mg/mL
Submitted references Differential expression of B29 (CD79b) and mb-1 (CD79a) proteins in acute lymphoblastic leukaemia.
Heterogeneity of immunoglobulin-associated molecules on human B cells identified by monoclonal antibodies.
Astsaturov IA, Matutes E, Morilla R, Seon BK, Mason DY, Farahat N, Catovsky D
Leukemia 1996 May;10(5):769-73
Leukemia 1996 May;10(5):769-73
Heterogeneity of immunoglobulin-associated molecules on human B cells identified by monoclonal antibodies.
Nakamura T, Kubagawa H, Cooper MD
Proceedings of the National Academy of Sciences of the United States of America 1992 Sep 15;89(18):8522-6
Proceedings of the National Academy of Sciences of the United States of America 1992 Sep 15;89(18):8522-6
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Supportive validation
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- Invitrogen Antibodies (provider)
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- Experimental details
- Staining of normal human peripheral blood cells with Anti-Human CD19 APC (Product # 17-0199-42) and 0.25 µg of Mouse IgG1 kappa Isotype Control Purified (Product # 14-4714-82) (left) or 0.25 µg of Anti-Human CD79b Purified (right) followed by F (ab')2 Anti-Mouse IgG PE (Product # 12-4012). Cells in the lymphocyte gate were used for analysis.
