FNab08584

antibody from FineTest Biotech

Targeting: TEAD4 EFTR-2, RTEF-1, TCF13L1, TEF-3, TEFR-1

Western blot

ELISA

Immunoprecipitation

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Validation data

Product number: FNab08584 - Provider product page
Provider: FineTest Biotech
Product name: TEAD4 antibody
Antibody type: Polyclonal
Antigen: Recombinant protein fragment
Description: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition(EMT) induction. Binds specifically and non-cooperatively to the Sph and GT-IIC 'enhansons'(5'-GTGGAATGT-3') and activates transcription. Binds to the M-CAT motif.
Reactivity: Human, Mouse, Rat
Host: Rabbit
Conjugate: Unconjugated
Antigen sequence: TEA domain family member 4
Epitope: IgG
Isotype: IgG
Vial size: 100¦Ìg
Concentration: Immunogen affinity purified
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

TEAD4 protein structure - FNab08584 shown in red.