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- Antigen structure
- References [97]
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- Product number
- 14865-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#14865-1-AP, RRID:AB_11182164
- Product name
- SDHA antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SDHA antibody (Cat. #14865-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Macrophage MCT4 inhibition activates reparative genes and protects from atherosclerosis by histone H3 lysine 18 lactylation.
ECHDC2 inhibits the proliferation of gastric cancer cells by binding with NEDD4 to degrade MCCC2 and reduce aerobic glycolysis.
TREM2 deficiency impairs the energy metabolism of Schwann cells and exacerbates peripheral neurological deficits.
Peroxiredoxin 3 has a crucial role in the macrophage polarization by regulating mitochondrial homeostasis.
Pseudorabies virus manipulates mitochondrial tryptophanyl-tRNA synthetase 2 for viral replication.
Ribosome-targeting antibiotic control NLRP3-mediated inflammation by inhibiting mitochondrial DNA synthesis.
AMPK phosphorylation of FNIP1 (S220) controls mitochondrial function and muscle fuel utilization during exercise.
MT-TN mutations lead to progressive mitochondrial encephalopathy and promotes mitophagy.
Mitochondrial dysfunction induced by HIF-1α under hypoxia contributes to the development of gastric mucosal lesions.
SIRT4 loss reprograms intestinal nucleotide metabolism to support proliferation following perturbation of homeostasis.
Ergothioneine boosts mitochondrial respiration and exercise performance via direct activation of MPST.
Comprehensive analysis of the prognosis, tumor microenvironment, and immunotherapy response of SDHs in colon adenocarcinoma.
Dietary cobalt oxide nanoparticles alleviate aging through activation of mitochondrial UPR in Caenorhabditis elegans.
Effect of postharvest nicotinamide treatment on NAD(+) metabolism and redox status in strawberry fruit during storage.
A mitochondrial EglN1-AMPKα axis drives breast cancer progression by enhancing metabolic adaptation to hypoxic stress.
ZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury.
Cardiolipin and OPA1 Team up for Methamphetamine-Induced Locomotor Activity by Promoting Neuronal Mitochondrial Fusion in the Nucleus Accumbens of Mice.
Multi-Cell Line Analysis of Lysosomal Proteomes Reveals Unique Features and Novel Lysosomal Proteins.
Mitochondrial Methionyl-tRNA Formyltransferase Deficiency Alleviates Metaflammation by Modulating Mitochondrial Activity in Mice.
Impaired mitophagy causes mitochondrial DNA leakage and STING activation in ultraviolet B-irradiated human keratinocytes HaCaT.
5-HEPE reduces obesity and insulin resistance by promoting adipose tissue browning through GPR119/AMPK/PGC1α activation.
Delivery of low-density lipoprotein from endocytic carriers to mitochondria supports steroidogenesis.
Rab8a as a mitochondrial receptor for lipid droplets in skeletal muscle.
Synergistic effects of lipopolysaccharide and rotenone on dopamine neuronal damage in rats.
NRF1-mediated mitochondrial biogenesis antagonizes innate antiviral immunity.
Saturated fatty acids increase LPI to reduce FUNDC1 dimerization and stability and mitochondrial function.
Diosgenin Inhibits ROS Generation by Modulating NOX4 and Mitochondrial Respiratory Chain and Suppresses Apoptosis in Diabetic Nephropathy.
Activation of Dynamin-Related Protein 1 and Induction of Mitochondrial Apoptosis by Exosome-Rifampicin Nanoparticles Exerts Anti-Osteosarcoma Effect.
Inhibition of High-Temperature Requirement Protein A2 Protease Activity Represses Myogenic Differentiation via UPRmt.
Bromodomain-containing protein 4 (BRD4) as an epigenetic regulator of fatty acid metabolism genes and ferroptosis.
Hydrogen Peroxide Promotes the Production of Radiation-Derived EVs Containing Mitochondrial Proteins.
Cross-linking of the endolysosomal system reveals potential flotillin structures and cargo.
Loss of Sam50 in hepatocytes induces cardiolipin-dependent mitochondrial membrane remodeling to trigger mtDNA release and liver injury.
[Effects of Long-Term Ethanol Consumption on Learning-Memory Functions in Mice and the Mechanisms Involved].
Specialist multidisciplinary input maximises rare disease diagnoses from whole genome sequencing.
Nuclear Receptor NR1D1 Regulates Abdominal Aortic Aneurysm Development by Targeting the Mitochondrial Tricarboxylic Acid Cycle Enzyme Aconitase-2.
FNIP1 regulates adipocyte browning and systemic glucose homeostasis in mice by shaping intracellular calcium dynamics.
LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development.
Maternal Herpesviridae infection during pregnancy alters midbrain dopaminergic signatures in adult offspring.
Mitochondrial proteostasis stress in muscle drives a long-range protective response to alleviate dietary obesity independently of ATF4.
A redox cycle with complex II prioritizes sulfide quinone oxidoreductase-dependent H(2)S oxidation.
Global mitochondrial protein import proteomics reveal distinct regulation by translation and translocation machinery.
Dopamine receptor D1 signaling stimulates lipolysis and browning of white adipocytes.
CHCHD2 and CHCHD10 regulate mitochondrial dynamics and integrated stress response.
Disuse-associated loss of the protease LONP1 in muscle impairs mitochondrial function and causes reduced skeletal muscle mass and strength.
Non-canonical phosphoglycerate dehydrogenase activity promotes liver cancer growth via mitochondrial translation and respiratory metabolism.
Role of molybdenum in material immunomodulation and periodontal wound healing: Targeting immunometabolism and mitochondrial function for macrophage modulation.
Mitochondrial protein hyperacetylation underpins heart failure with preserved ejection fraction in mice.
The Protective Effect of 1,25(OH)(2)D(3) on Myocardial Function is Mediated via Sirtuin 3-Regulated Fatty Acid Metabolism.
Increased Expression of DNA2 Was Linked to Poor Prognosis in Breast Cancer.
Empagliflozin Induces White Adipocyte Browning and Modulates Mitochondrial Dynamics in KK Cg-Ay/J Mice and Mouse Adipocytes.
Celecoxib reverses the glioblastoma chemo-resistance to temozolomide through mitochondrial metabolism.
The requirement for pyruvate dehydrogenase in leukemogenesis depends on cell lineage.
Proteomic analysis demonstrates the role of the quality control protease LONP1 in mitochondrial protein aggregation.
Low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk.
Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination.
ALS/FTD mutations in UBQLN2 are linked to mitochondrial dysfunction through loss-of-function in mitochondrial protein import.
Leber's Hereditary Optic Neuropathy Arising From the Synergy Between ND1 3635G>A Mutation and Mitochondrial YARS2 Mutations.
An animal model for mitochondrial tyrosyl-tRNA synthetase deficiency reveals links between oxidative phosphorylation and retinal function.
OMA1 reprograms metabolism under hypoxia to promote colorectal cancer development.
Endonuclease G promotes autophagy by suppressing mTOR signaling and activating the DNA damage response.
Deficiency of β-carotene oxygenase 2 induces mitochondrial fragmentation and activates the STING-IRF3 pathway in the mouse hypothalamus.
Spermine Protects Cardiomyocytes from High Glucose-Induced Energy Disturbance by Targeting the CaSR-gp78-Ubiquitin Proteasome System.
Fumarate is a terminal electron acceptor in the mammalian electron transport chain.
Tissue-specific expression atlas of murine mitochondrial tRNAs.
APOL1 risk variants affect podocyte lipid homeostasis and energy production in focal segmental glomerulosclerosis.
Drp1-mediated mitochondrial fission contributes to baicalein-induced apoptosis and autophagy in lung cancer via activation of AMPK signaling pathway.
Histochemical and immunohistochemical staining methods to visualize mitochondrial proteins and activity.
Myc-mediated SDHA acetylation triggers epigenetic regulation of gene expression and tumorigenesis.
p53/PGC‑1α‑mediated mitochondrial dysfunction promotes PC3 prostate cancer cell apoptosis.
Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis.
Sam50-Mic19-Mic60 axis determines mitochondrial cristae architecture by mediating mitochondrial outer and inner membrane contact.
Fluoride-induced renal dysfunction via respiratory chain complex abnormal expression and fusion elevation in mice.
Mitochondrial respiratory chain damage and mitochondrial fusion disorder are involved in liver dysfunction of fluoride-induced mice.
Ginkgolic Acids Impair Mitochondrial Function by Decreasing Mitochondrial Biogenesis and Promoting FUNDC1-Dependent Mitophagy.
Artemisinin suppresses hepatocellular carcinoma cell growth, migration and invasion by targeting cellular bioenergetics and Hippo-YAP signaling.
Increase of core temperature affected the progression of kidney injury by repeated heat stress exposure.
Benzoylaconine induces mitochondrial biogenesis in mice via activating AMPK signaling cascade.
The combination of metformin and 2-deoxyglucose significantly inhibits cyst formation in miniature pigs with polycystic kidney disease.
Deletion of Gtpbp3 in zebrafish revealed the hypertrophic cardiomyopathy manifested by aberrant mitochondrial tRNA metabolism.
Mitochondrial respiratory chain dysfunction mediated by ROS is a primary point of fluoride-induced damage in Hepa1-6 cells.
Promotion of Mitochondrial Biogenesis via Activation of AMPK-PGC1ɑ Signaling Pathway by Ginger (Zingiber officinale Roscoe) Extract, and Its Major Active Component 6-Gingerol.
SIRT5-mediated SDHA desuccinylation promotes clear cell renal cell carcinoma tumorigenesis.
Mitophagy Directs Muscle-Adipose Crosstalk to Alleviate Dietary Obesity.
AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity.
Lack of β, β-carotene-9', 10'-oxygenase 2 leads to hepatic mitochondrial dysfunction and cellular oxidative stress in mice.
CUE domain-containing protein 2 promotes the Warburg effect and tumorigenesis.
Calcium sensing receptor protects high glucose-induced energy metabolism disorder via blocking gp78-ubiquitin proteasome pathway.
The changes in glucose metabolism and cell proliferation in the kidneys of polycystic kidney disease mini-pig models.
DJ-1 modulates mitochondrial response to oxidative stress: clues from a novel diagnosis of PARK7.
CYC1 Predicts Poor Prognosis in Patients with Breast Cancer.
Oral quercetin administration transiently protects respiratory function in dystrophin-deficient mice.
Mic60/Mitofilin determines MICOS assembly essential for mitochondrial dynamics and mtDNA nucleoid organization.
COA7 (C1orf163/RESA1) mutations associated with mitochondrial leukoencephalopathy and cytochrome c oxidase deficiency.
Exercise Inducible Lactate Dehydrogenase B Regulates Mitochondrial Function in Skeletal Muscle.
EglN2 associates with the NRF1-PGC1α complex and controls mitochondrial function in breast cancer.
Lin28/let-7 axis regulates aerobic glycolysis and cancer progression via PDK1.
Zhang Y, Jiang H, Dong M, Min J, He X, Tan Y, Liu F, Chen M, Chen X, Yin Q, Zheng L, Shao Y, Li X, Chen H
Cell reports 2024 May 28;43(5):114180
Cell reports 2024 May 28;43(5):114180
ECHDC2 inhibits the proliferation of gastric cancer cells by binding with NEDD4 to degrade MCCC2 and reduce aerobic glycolysis.
He J, Yi J, Ji L, Dai L, Chen Y, Xue W
Molecular medicine (Cambridge, Mass.) 2024 May 23;30(1):69
Molecular medicine (Cambridge, Mass.) 2024 May 23;30(1):69
TREM2 deficiency impairs the energy metabolism of Schwann cells and exacerbates peripheral neurological deficits.
Zhang N, Ji Q, Chen Y, Wen X, Shan F
Cell death & disease 2024 Mar 7;15(3):193
Cell death & disease 2024 Mar 7;15(3):193
Peroxiredoxin 3 has a crucial role in the macrophage polarization by regulating mitochondrial homeostasis.
Huang W, Wang L, Huang Z, Sun Z, Zheng B
Respiratory research 2024 Mar 2;25(1):110
Respiratory research 2024 Mar 2;25(1):110
Pseudorabies virus manipulates mitochondrial tryptophanyl-tRNA synthetase 2 for viral replication.
Li XQ, Cai MP, Wang MY, Shi BW, Yang GY, Wang J, Chu BB, Ming SL
Virologica Sinica 2024 Jun;39(3):403-413
Virologica Sinica 2024 Jun;39(3):403-413
Ribosome-targeting antibiotic control NLRP3-mediated inflammation by inhibiting mitochondrial DNA synthesis.
Liu S, Tan M, Cai J, Li C, Yang M, Sun X, He B
Free radical biology & medicine 2024 Jan;210:75-84
Free radical biology & medicine 2024 Jan;210:75-84
AMPK phosphorylation of FNIP1 (S220) controls mitochondrial function and muscle fuel utilization during exercise.
Xiao L, Yin Y, Sun Z, Liu J, Jia Y, Yang L, Mao Y, Peng S, Xie Z, Fang L, Li J, Xie X, Gan Z
Science advances 2024 Feb 9;10(6):eadj2752
Science advances 2024 Feb 9;10(6):eadj2752
MT-TN mutations lead to progressive mitochondrial encephalopathy and promotes mitophagy.
Duan H, Pan C, Wu T, Peng J, Yang L
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167043
Biochimica et biophysica acta. Molecular basis of disease 2024 Apr;1870(4):167043
Mitochondrial dysfunction induced by HIF-1α under hypoxia contributes to the development of gastric mucosal lesions.
Xiao Y, Liu X, Xie K, Luo J, Zhang Y, Huang X, Luo J, Tan S
Clinical and translational medicine 2024 Apr;14(4):e1653
Clinical and translational medicine 2024 Apr;14(4):e1653
SIRT4 loss reprograms intestinal nucleotide metabolism to support proliferation following perturbation of homeostasis.
Tucker SA, Hu SH, Vyas S, Park A, Joshi S, Inal A, Lam T, Tan E, Haigis KM, Haigis MC
Cell reports 2024 Apr 23;43(4):113975
Cell reports 2024 Apr 23;43(4):113975
Ergothioneine boosts mitochondrial respiration and exercise performance via direct activation of MPST.
Sprenger HG, Mittenbühler MJ, Sun Y, Van Vranken JG, Schindler S, Jayaraj A, Khetarpal SA, Vargas-Castillo A, Puszynska AM, Spinelli JB, Armani A, Kunchok T, Ryback B, Seo HS, Song K, Sebastian L, O'Young C, Braithwaite C, Dhe-Paganon S, Burger N, Mills EL, Gygi SP, Arthanari H, Chouchani ET, Sabatini DM, Spiegelman BM
bioRxiv : the preprint server for biology 2024 Apr 10;
bioRxiv : the preprint server for biology 2024 Apr 10;
Comprehensive analysis of the prognosis, tumor microenvironment, and immunotherapy response of SDHs in colon adenocarcinoma.
Nan H, Guo P, Fan J, Zeng W, Hu C, Zheng C, Pan B, Cao Y, Ge Y, Xue X, Li W, Lin K
Frontiers in immunology 2023;14:1093974
Frontiers in immunology 2023;14:1093974
Dietary cobalt oxide nanoparticles alleviate aging through activation of mitochondrial UPR in Caenorhabditis elegans.
Cong W, Wang Y, Yuan C, Xu M, Wang H, Hu Y, Dai X, Weng Y, Timashev P, Liang XJ, Huang Y
Theranostics 2023;13(10):3276-3289
Theranostics 2023;13(10):3276-3289
Effect of postharvest nicotinamide treatment on NAD(+) metabolism and redox status in strawberry fruit during storage.
Piechowiak T, Skóra B, Balawejder M
Phytochemistry 2023 Sep;213:113766
Phytochemistry 2023 Sep;213:113766
A mitochondrial EglN1-AMPKα axis drives breast cancer progression by enhancing metabolic adaptation to hypoxic stress.
Jiang W, Zhang M, Gao C, Yan C, Gao R, He Z, Wei X, Xiong J, Ruan Z, Yang Q, Li J, Li Q, Zhong Z, Zhang M, Yuan Q, Hu H, Wang S, Hu MM, Cai C, Wu GS, Jiang C, Zhang YL, Zhang CS, Zhang J
The EMBO journal 2023 Oct 16;42(20):e113743
The EMBO journal 2023 Oct 16;42(20):e113743
ZHX2 emerges as a negative regulator of mitochondrial oxidative phosphorylation during acute liver injury.
Zhang Y, Fan Y, Hu H, Zhang X, Wang Z, Wu Z, Wang L, Yu X, Song X, Xiang P, Zhang X, Wang T, Tan S, Li C, Gao L, Liang X, Li S, Li N, Yue X, Ma C
Nature communications 2023 Nov 18;14(1):7527
Nature communications 2023 Nov 18;14(1):7527
Cardiolipin and OPA1 Team up for Methamphetamine-Induced Locomotor Activity by Promoting Neuronal Mitochondrial Fusion in the Nucleus Accumbens of Mice.
Wang L, Wei Q, Xu R, Chen Y, Li S, Bu Q, Zhao Y, Li H, Zhao Y, Jiang L, Chen Y, Dai Y, Zhao Y, Cen X
ACS chemical neuroscience 2023 May 3;14(9):1585-1601
ACS chemical neuroscience 2023 May 3;14(9):1585-1601
Multi-Cell Line Analysis of Lysosomal Proteomes Reveals Unique Features and Novel Lysosomal Proteins.
Akter F, Bonini S, Ponnaiyan S, Kögler-Mohrbacher B, Bleibaum F, Damme M, Renard BY, Winter D
Molecular & cellular proteomics : MCP 2023 Mar;22(3):100509
Molecular & cellular proteomics : MCP 2023 Mar;22(3):100509
Mitochondrial Methionyl-tRNA Formyltransferase Deficiency Alleviates Metaflammation by Modulating Mitochondrial Activity in Mice.
Sun X, Liu S, Cai J, Yang M, Li C, Tan M, He B
International journal of molecular sciences 2023 Mar 22;24(6)
International journal of molecular sciences 2023 Mar 22;24(6)
Impaired mitophagy causes mitochondrial DNA leakage and STING activation in ultraviolet B-irradiated human keratinocytes HaCaT.
Li C, Zhu Y, Liu W, Xiang W, He S, Hayashi T, Mizuno K, Hattori S, Fujisaki H, Ikejima T
Archives of biochemistry and biophysics 2023 Mar 15;737:109553
Archives of biochemistry and biophysics 2023 Mar 15;737:109553
5-HEPE reduces obesity and insulin resistance by promoting adipose tissue browning through GPR119/AMPK/PGC1α activation.
Zong Y, Wang M, Liu Y, Suo X, Fan G, Yang X
Life sciences 2023 Jun 15;323:121703
Life sciences 2023 Jun 15;323:121703
Delivery of low-density lipoprotein from endocytic carriers to mitochondria supports steroidogenesis.
Zhou YX, Wei J, Deng G, Hu A, Sun PY, Zhao X, Song BL, Luo J
Nature cell biology 2023 Jul;25(7):937-949
Nature cell biology 2023 Jul;25(7):937-949
Rab8a as a mitochondrial receptor for lipid droplets in skeletal muscle.
Ouyang Q, Chen Q, Ke S, Ding L, Yang X, Rong P, Feng W, Cao Y, Wang Q, Li M, Su S, Wei W, Liu M, Liu J, Zhang X, Li JZ, Wang HY, Chen S
Developmental cell 2023 Feb 27;58(4):289-305.e6
Developmental cell 2023 Feb 27;58(4):289-305.e6
Synergistic effects of lipopolysaccharide and rotenone on dopamine neuronal damage in rats.
He JY, Li DD, Wen Q, Qin TY, Long H, Zhang SB, Zhang F
CNS neuroscience & therapeutics 2023 Aug;29(8):2281-2291
CNS neuroscience & therapeutics 2023 Aug;29(8):2281-2291
NRF1-mediated mitochondrial biogenesis antagonizes innate antiviral immunity.
Zhao T, Zhang J, Lei H, Meng Y, Cheng H, Zhao Y, Geng G, Mu C, Chen L, Liu Q, Luo Q, Zhang C, Long Y, Su J, Wang Y, Li Z, Sun J, Chen G, Li Y, Liao X, Shang Y, Hu G, Chen Q, Zhu Y
The EMBO journal 2023 Aug 15;42(16):e113258
The EMBO journal 2023 Aug 15;42(16):e113258
Saturated fatty acids increase LPI to reduce FUNDC1 dimerization and stability and mitochondrial function.
Chen L, Zhang Q, Meng Y, Zhao T, Mu C, Fu C, Deng C, Feng J, Du S, Liu W, Geng G, Ma K, Cheng H, Liu Q, Luo Q, Zhang J, Du Z, Cao L, Wang H, Liu Y, Lin J, Chen G, Liu L, Lam SM, Shui G, Zhu Y, Chen Q
EMBO reports 2023 Apr 5;24(4):e54731
EMBO reports 2023 Apr 5;24(4):e54731
Diosgenin Inhibits ROS Generation by Modulating NOX4 and Mitochondrial Respiratory Chain and Suppresses Apoptosis in Diabetic Nephropathy.
Zhong Y, Wang L, Jin R, Liu J, Luo R, Zhang Y, Zhu L, Peng X
Nutrients 2023 Apr 30;15(9)
Nutrients 2023 Apr 30;15(9)
Activation of Dynamin-Related Protein 1 and Induction of Mitochondrial Apoptosis by Exosome-Rifampicin Nanoparticles Exerts Anti-Osteosarcoma Effect.
Chen W, Lin W, Yu N, Zhang L, Wu Z, Chen Y, Li Z, Gong F, Li N, Chen X, He X, Wu Y, Zeng X, Yueh Y, Xu R, Ji G
International journal of nanomedicine 2022;17:5431-5446
International journal of nanomedicine 2022;17:5431-5446
Inhibition of High-Temperature Requirement Protein A2 Protease Activity Represses Myogenic Differentiation via UPRmt.
Sun H, Shen L, Zhang P, Lin F, Ma J, Wu Y, Yu H, Sun L
International journal of molecular sciences 2022 Oct 4;23(19)
International journal of molecular sciences 2022 Oct 4;23(19)
Bromodomain-containing protein 4 (BRD4) as an epigenetic regulator of fatty acid metabolism genes and ferroptosis.
Yang M, Liu K, Chen P, Zhu H, Wang J, Huang J
Cell death & disease 2022 Oct 29;13(10):912
Cell death & disease 2022 Oct 29;13(10):912
Hydrogen Peroxide Promotes the Production of Radiation-Derived EVs Containing Mitochondrial Proteins.
Miller CE, Xu F, Zhao Y, Luo W, Zhong W, Meyer K, Jayswal R, Weiss HL, St Clair WH, St Clair DK, Chaiswing L
Antioxidants (Basel, Switzerland) 2022 Oct 27;11(11)
Antioxidants (Basel, Switzerland) 2022 Oct 27;11(11)
Cross-linking of the endolysosomal system reveals potential flotillin structures and cargo.
Singh J, Elhabashy H, Muthukottiappan P, Stepath M, Eisenacher M, Kohlbacher O, Gieselmann V, Winter D
Nature communications 2022 Oct 20;13(1):6212
Nature communications 2022 Oct 20;13(1):6212
Loss of Sam50 in hepatocytes induces cardiolipin-dependent mitochondrial membrane remodeling to trigger mtDNA release and liver injury.
Chen L, Dong J, Liao S, Wang S, Wu Z, Zuo M, Liu B, Yan C, Chen Y, He H, Meng Q, Song Z
Hepatology (Baltimore, Md.) 2022 Nov;76(5):1389-1408
Hepatology (Baltimore, Md.) 2022 Nov;76(5):1389-1408
[Effects of Long-Term Ethanol Consumption on Learning-Memory Functions in Mice and the Mechanisms Involved].
Zhou J, Wu W, Ji LW, Li Q, Liang Y, Li T, Yang L
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 2022 Nov;53(6):1049-1054
Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition 2022 Nov;53(6):1049-1054
Specialist multidisciplinary input maximises rare disease diagnoses from whole genome sequencing.
Macken WL, Falabella M, McKittrick C, Pizzamiglio C, Ellmers R, Eggleton K, Woodward CE, Patel Y, Labrum R, Genomics England Research Consortium, Phadke R, Reilly MM, DeVile C, Sarkozy A, Footitt E, Davison J, Rahman S, Houlden H, Bugiardini E, Quinlivan R, Hanna MG, Vandrovcova J, Pitceathly RDS
Nature communications 2022 Nov 7;13(1):6324
Nature communications 2022 Nov 7;13(1):6324
Nuclear Receptor NR1D1 Regulates Abdominal Aortic Aneurysm Development by Targeting the Mitochondrial Tricarboxylic Acid Cycle Enzyme Aconitase-2.
Sun LY, Lyu YY, Zhang HY, Shen Z, Lin GQ, Geng N, Wang YL, Huang L, Feng ZH, Guo X, Lin N, Ding S, Yuan AC, Zhang L, Qian K, Pu J
Circulation 2022 Nov 22;146(21):1591-1609
Circulation 2022 Nov 22;146(21):1591-1609
FNIP1 regulates adipocyte browning and systemic glucose homeostasis in mice by shaping intracellular calcium dynamics.
Yin Y, Xu D, Mao Y, Xiao L, Sun Z, Liu J, Zhou D, Xu Z, Liu L, Fu T, Ding C, Guo Q, Sun W, Zhou Z, Yang L, Jia Y, Chen X, Gan Z
The Journal of experimental medicine 2022 May 2;219(5)
The Journal of experimental medicine 2022 May 2;219(5)
LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development.
Zhao K, Huang X, Zhao W, Lu B, Yang Z
Development (Cambridge, England) 2022 Mar 15;149(6)
Development (Cambridge, England) 2022 Mar 15;149(6)
Maternal Herpesviridae infection during pregnancy alters midbrain dopaminergic signatures in adult offspring.
Burmeister AR, Gordevicius J, Paul EN, Houck C, George S, Escobar Galvis ML, Sha Q, Brundin P, Pospisilik JA, Racicot K, Brundin L
Neurobiology of disease 2022 Jul;169:105720
Neurobiology of disease 2022 Jul;169:105720
Mitochondrial proteostasis stress in muscle drives a long-range protective response to alleviate dietary obesity independently of ATF4.
Guo Q, Xu Z, Zhou D, Fu T, Wang W, Sun W, Xiao L, Liu L, Ding C, Yin Y, Zhou Z, Sun Z, Zhu Y, Zhou W, Jia Y, Xue J, Chen Y, Chen XW, Piao HL, Lu B, Gan Z
Science advances 2022 Jul 29;8(30):eabo0340
Science advances 2022 Jul 29;8(30):eabo0340
A redox cycle with complex II prioritizes sulfide quinone oxidoreductase-dependent H(2)S oxidation.
Kumar R, Landry AP, Guha A, Vitvitsky V, Lee HJ, Seike K, Reddy P, Lyssiotis CA, Banerjee R
The Journal of biological chemistry 2022 Jan;298(1):101435
The Journal of biological chemistry 2022 Jan;298(1):101435
Global mitochondrial protein import proteomics reveal distinct regulation by translation and translocation machinery.
Schäfer JA, Bozkurt S, Michaelis JB, Klann K, Münch C
Molecular cell 2022 Jan 20;82(2):435-446.e7
Molecular cell 2022 Jan 20;82(2):435-446.e7
Dopamine receptor D1 signaling stimulates lipolysis and browning of white adipocytes.
Yu J, Zhu J, Deng J, Shen J, Du F, Wu X, Chen Y, Li M, Wen Q, Xiao Z, Zhao Y
Biochemical and biophysical research communications 2022 Jan 15;588:83-89
Biochemical and biophysical research communications 2022 Jan 15;588:83-89
CHCHD2 and CHCHD10 regulate mitochondrial dynamics and integrated stress response.
Ruan Y, Hu J, Che Y, Liu Y, Luo Z, Cheng J, Han Q, He H, Zhou Q
Cell death & disease 2022 Feb 16;13(2):156
Cell death & disease 2022 Feb 16;13(2):156
Disuse-associated loss of the protease LONP1 in muscle impairs mitochondrial function and causes reduced skeletal muscle mass and strength.
Xu Z, Fu T, Guo Q, Zhou D, Sun W, Zhou Z, Chen X, Zhang J, Liu L, Xiao L, Yin Y, Jia Y, Pang E, Chen Y, Pan X, Fang L, Zhu MS, Fei W, Lu B, Gan Z
Nature communications 2022 Feb 16;13(1):894
Nature communications 2022 Feb 16;13(1):894
Non-canonical phosphoglycerate dehydrogenase activity promotes liver cancer growth via mitochondrial translation and respiratory metabolism.
Shu Y, Hao Y, Feng J, Liu H, Li ST, Feng J, Jiang Z, Ye L, Zhou Y, Sun Y, Zhou Z, Wei H, Gao P, Zhang H, Sun L
The EMBO journal 2022 Dec 1;41(23):e111550
The EMBO journal 2022 Dec 1;41(23):e111550
Role of molybdenum in material immunomodulation and periodontal wound healing: Targeting immunometabolism and mitochondrial function for macrophage modulation.
He XT, Li X, Zhang M, Tian BM, Sun LJ, Bi CS, Deng DK, Zhou H, Qu HL, Wu C, Chen FM
Biomaterials 2022 Apr;283:121439
Biomaterials 2022 Apr;283:121439
Mitochondrial protein hyperacetylation underpins heart failure with preserved ejection fraction in mice.
Liu X, Zhang Y, Deng Y, Yang L, Ou W, Xie M, Ding L, Jiang C, Yu H, Li Q, Li T
Journal of molecular and cellular cardiology 2022 Apr;165:76-85
Journal of molecular and cellular cardiology 2022 Apr;165:76-85
The Protective Effect of 1,25(OH)(2)D(3) on Myocardial Function is Mediated via Sirtuin 3-Regulated Fatty Acid Metabolism.
Yang J, Zhang Y, Pan Y, Sun C, Liu Z, Liu N, Fu Y, Li X, Li Y, Kong J
Frontiers in cell and developmental biology 2021;9:627135
Frontiers in cell and developmental biology 2021;9:627135
Increased Expression of DNA2 Was Linked to Poor Prognosis in Breast Cancer.
Han Y, Zhang Z, Wang Z, Sun S
Disease markers 2021;2021:8860728
Disease markers 2021;2021:8860728
Empagliflozin Induces White Adipocyte Browning and Modulates Mitochondrial Dynamics in KK Cg-Ay/J Mice and Mouse Adipocytes.
Xu L, Xu C, Liu X, Li X, Li T, Yu X, Xue M, Yang J, Kosmas CE, Moris D, Sanchis-Gomar F, Yoshida N, Berger NA, Aronow WS, Sun B, Chen L
Frontiers in physiology 2021;12:745058
Frontiers in physiology 2021;12:745058
Celecoxib reverses the glioblastoma chemo-resistance to temozolomide through mitochondrial metabolism.
Yin D, Jin G, He H, Zhou W, Fan Z, Gong C, Zhao J, Xiong H
Aging 2021 Sep 8;13(17):21268-21282
Aging 2021 Sep 8;13(17):21268-21282
The requirement for pyruvate dehydrogenase in leukemogenesis depends on cell lineage.
Jun S, Mahesula S, Mathews TP, Martin-Sandoval MS, Zhao Z, Piskounova E, Agathocleous M
Cell metabolism 2021 Sep 7;33(9):1777-1792.e8
Cell metabolism 2021 Sep 7;33(9):1777-1792.e8
Proteomic analysis demonstrates the role of the quality control protease LONP1 in mitochondrial protein aggregation.
Pollecker K, Sylvester M, Voos W
The Journal of biological chemistry 2021 Oct;297(4):101134
The Journal of biological chemistry 2021 Oct;297(4):101134
Low chorionic villous succinate accumulation associates with recurrent spontaneous abortion risk.
Wang XH, Xu S, Zhou XY, Zhao R, Lin Y, Cao J, Zang WD, Tao H, Xu W, Li MQ, Zhao SM, Jin LP, Zhao JY
Nature communications 2021 Jun 8;12(1):3428
Nature communications 2021 Jun 8;12(1):3428
Parkin-independent mitophagy via Drp1-mediated outer membrane severing and inner membrane ubiquitination.
Oshima Y, Cartier E, Boyman L, Verhoeven N, Polster BM, Huang W, Kane M, Lederer WJ, Karbowski M
The Journal of cell biology 2021 Jun 7;220(6)
The Journal of cell biology 2021 Jun 7;220(6)
ALS/FTD mutations in UBQLN2 are linked to mitochondrial dysfunction through loss-of-function in mitochondrial protein import.
Lin BC, Phung TH, Higgins NR, Greenslade JE, Prado MA, Finley D, Karbowski M, Polster BM, Monteiro MJ
Human molecular genetics 2021 Jun 17;30(13):1230-1246
Human molecular genetics 2021 Jun 17;30(13):1230-1246
Leber's Hereditary Optic Neuropathy Arising From the Synergy Between ND1 3635G>A Mutation and Mitochondrial YARS2 Mutations.
Jin X, Zhang J, Yi Q, Meng F, Yu J, Ji Y, Mo JQ, Tong Y, Jiang P, Guan MX
Investigative ophthalmology & visual science 2021 Jun 1;62(7):22
Investigative ophthalmology & visual science 2021 Jun 1;62(7):22
An animal model for mitochondrial tyrosyl-tRNA synthetase deficiency reveals links between oxidative phosphorylation and retinal function.
Jin X, Zhang Z, Nie Z, Wang C, Meng F, Yi Q, Chen M, Sun J, Zou J, Jiang P, Guan MX
The Journal of biological chemistry 2021 Jan-Jun;296:100437
The Journal of biological chemistry 2021 Jan-Jun;296:100437
OMA1 reprograms metabolism under hypoxia to promote colorectal cancer development.
Wu Z, Zuo M, Zeng L, Cui K, Liu B, Yan C, Chen L, Dong J, Shangguan F, Hu W, He H, Lu B, Song Z
EMBO reports 2021 Jan 7;22(1):e50827
EMBO reports 2021 Jan 7;22(1):e50827
Endonuclease G promotes autophagy by suppressing mTOR signaling and activating the DNA damage response.
Wang W, Li J, Tan J, Wang M, Yang J, Zhang ZM, Li C, Basnakian AG, Tang HW, Perrimon N, Zhou Q
Nature communications 2021 Jan 20;12(1):476
Nature communications 2021 Jan 20;12(1):476
Deficiency of β-carotene oxygenase 2 induces mitochondrial fragmentation and activates the STING-IRF3 pathway in the mouse hypothalamus.
Wu L, Guo X, Wong SY, Lu P, Hartson SD, Medeiros DM, Wang W, Clarke SL, Lucas EA, Smith BJ, Chowanadisai W, Lin D
The Journal of nutritional biochemistry 2021 Feb;88:108542
The Journal of nutritional biochemistry 2021 Feb;88:108542
Spermine Protects Cardiomyocytes from High Glucose-Induced Energy Disturbance by Targeting the CaSR-gp78-Ubiquitin Proteasome System.
Wang Y, Wang Y, Li F, Zhang X, Li H, Yang G, Xu C, Wei C
Cardiovascular drugs and therapy 2021 Feb;35(1):73-85
Cardiovascular drugs and therapy 2021 Feb;35(1):73-85
Fumarate is a terminal electron acceptor in the mammalian electron transport chain.
Spinelli JB, Rosen PC, Sprenger HG, Puszynska AM, Mann JL, Roessler JM, Cangelosi AL, Henne A, Condon KJ, Zhang T, Kunchok T, Lewis CA, Chandel NS, Sabatini DM
Science (New York, N.Y.) 2021 Dec 3;374(6572):1227-1237
Science (New York, N.Y.) 2021 Dec 3;374(6572):1227-1237
Tissue-specific expression atlas of murine mitochondrial tRNAs.
He Q, He X, Xiao Y, Zhao Q, Ye Z, Cui L, Chen Y, Guan MX
The Journal of biological chemistry 2021 Aug;297(2):100960
The Journal of biological chemistry 2021 Aug;297(2):100960
APOL1 risk variants affect podocyte lipid homeostasis and energy production in focal segmental glomerulosclerosis.
Ge M, Molina J, Ducasa GM, Mallela SK, Varona Santos J, Mitrofanova A, Kim JJ, Liu X, Sloan A, Mendez AJ, Banerjee S, Liu S, Szeto HH, Shin MK, Hoek M, Kopp JB, Fontanesi F, Merscher S, Fornoni A
Human molecular genetics 2021 Apr 26;30(3-4):182-197
Human molecular genetics 2021 Apr 26;30(3-4):182-197
Drp1-mediated mitochondrial fission contributes to baicalein-induced apoptosis and autophagy in lung cancer via activation of AMPK signaling pathway.
Deng X, Liu J, Liu L, Sun X, Huang J, Dong J
International journal of biological sciences 2020;16(8):1403-1416
International journal of biological sciences 2020;16(8):1403-1416
Histochemical and immunohistochemical staining methods to visualize mitochondrial proteins and activity.
Franco-Iborra S, Tanji K
Methods in cell biology 2020;155:247-270
Methods in cell biology 2020;155:247-270
Myc-mediated SDHA acetylation triggers epigenetic regulation of gene expression and tumorigenesis.
Li ST, Huang D, Shen S, Cai Y, Xing S, Wu G, Jiang Z, Hao Y, Yuan M, Wang N, Zhu L, Yan R, Yang D, Wang L, Liu Z, Hu X, Zhou R, Qu K, Li A, Duan X, Zhang H, Gao P
Nature metabolism 2020 Mar;2(3):256-269
Nature metabolism 2020 Mar;2(3):256-269
p53/PGC‑1α‑mediated mitochondrial dysfunction promotes PC3 prostate cancer cell apoptosis.
Li J, Li Y, Chen L, Yu B, Xue Y, Guo R, Su J, Liu Y, Sun L
Molecular medicine reports 2020 Jul;22(1):155-164
Molecular medicine reports 2020 Jul;22(1):155-164
Excessive Polyamine Generation in Keratinocytes Promotes Self-RNA Sensing by Dendritic Cells in Psoriasis.
Lou F, Sun Y, Xu Z, Niu L, Wang Z, Deng S, Liu Z, Zhou H, Bai J, Yin Q, Cai X, Sun L, Wang H, Li Q, Wu Z, Chen X, Gu J, Shi YL, Tao W, Ginhoux F, Wang H
Immunity 2020 Jul 14;53(1):204-216.e10
Immunity 2020 Jul 14;53(1):204-216.e10
Sam50-Mic19-Mic60 axis determines mitochondrial cristae architecture by mediating mitochondrial outer and inner membrane contact.
Tang J, Zhang K, Dong J, Yan C, Hu C, Ji H, Chen L, Chen S, Zhao H, Song Z
Cell death and differentiation 2020 Jan;27(1):146-160
Cell death and differentiation 2020 Jan;27(1):146-160
Fluoride-induced renal dysfunction via respiratory chain complex abnormal expression and fusion elevation in mice.
Wang HW, Zhu SQ, Liu J, Miao CY, Zhang Y, Zhou BH
Chemosphere 2020 Jan;238:124607
Chemosphere 2020 Jan;238:124607
Mitochondrial respiratory chain damage and mitochondrial fusion disorder are involved in liver dysfunction of fluoride-induced mice.
Wang HW, Liu J, Wei SS, Zhao WP, Zhu SQ, Zhou BH
Chemosphere 2020 Feb;241:125099
Chemosphere 2020 Feb;241:125099
Ginkgolic Acids Impair Mitochondrial Function by Decreasing Mitochondrial Biogenesis and Promoting FUNDC1-Dependent Mitophagy.
Wang W, Wang M, Ruan Y, Tan J, Wang H, Yang T, Li J, Zhou Q
Journal of agricultural and food chemistry 2019 Sep 11;67(36):10097-10106
Journal of agricultural and food chemistry 2019 Sep 11;67(36):10097-10106
Artemisinin suppresses hepatocellular carcinoma cell growth, migration and invasion by targeting cellular bioenergetics and Hippo-YAP signaling.
Li Y, Lu J, Chen Q, Han S, Shao H, Chen P, Jin Q, Yang M, Shangguan F, Fei M, Wang L, Liu Y, Liu N, Lu B
Archives of toxicology 2019 Nov;93(11):3367-3383
Archives of toxicology 2019 Nov;93(11):3367-3383
Increase of core temperature affected the progression of kidney injury by repeated heat stress exposure.
Sato Y, Roncal-Jimenez CA, Andres-Hernando A, Jensen T, Tolan DR, Sanchez-Lozada LG, Newman LS, Butler-Dawson J, Sorensen C, Glaser J, Miyazaki M, Diaz HF, Ishimoto T, Kosugi T, Maruyama S, Garcia GE, Lanaspa MA, Johnson RJ
American journal of physiology. Renal physiology 2019 Nov 1;317(5):F1111-F1121
American journal of physiology. Renal physiology 2019 Nov 1;317(5):F1111-F1121
Benzoylaconine induces mitochondrial biogenesis in mice via activating AMPK signaling cascade.
Deng XH, Liu JJ, Sun XJ, Dong JC, Huang JH
Acta pharmacologica Sinica 2019 May;40(5):658-665
Acta pharmacologica Sinica 2019 May;40(5):658-665
The combination of metformin and 2-deoxyglucose significantly inhibits cyst formation in miniature pigs with polycystic kidney disease.
Lian X, Wu X, Li Z, Zhang Y, Song K, Cai G, Li Q, Lin S, Chen X, Bai XY
British journal of pharmacology 2019 Mar;176(5):711-724
British journal of pharmacology 2019 Mar;176(5):711-724
Deletion of Gtpbp3 in zebrafish revealed the hypertrophic cardiomyopathy manifested by aberrant mitochondrial tRNA metabolism.
Chen D, Zhang Z, Chen C, Yao S, Yang Q, Li F, He X, Ai C, Wang M, Guan MX
Nucleic acids research 2019 Jun 4;47(10):5341-5355
Nucleic acids research 2019 Jun 4;47(10):5341-5355
Mitochondrial respiratory chain dysfunction mediated by ROS is a primary point of fluoride-induced damage in Hepa1-6 cells.
Wang HW, Zhang Y, Tan PP, Jia LS, Chen Y, Zhou BH
Environmental pollution (Barking, Essex : 1987) 2019 Dec;255(Pt 3):113359
Environmental pollution (Barking, Essex : 1987) 2019 Dec;255(Pt 3):113359
Promotion of Mitochondrial Biogenesis via Activation of AMPK-PGC1ɑ Signaling Pathway by Ginger (Zingiber officinale Roscoe) Extract, and Its Major Active Component 6-Gingerol.
Deng X, Zhang S, Wu J, Sun X, Shen Z, Dong J, Huang J
Journal of food science 2019 Aug;84(8):2101-2111
Journal of food science 2019 Aug;84(8):2101-2111
SIRT5-mediated SDHA desuccinylation promotes clear cell renal cell carcinoma tumorigenesis.
Ma Y, Qi Y, Wang L, Zheng Z, Zhang Y, Zheng J
Free radical biology & medicine 2019 Apr;134:458-467
Free radical biology & medicine 2019 Apr;134:458-467
Mitophagy Directs Muscle-Adipose Crosstalk to Alleviate Dietary Obesity.
Fu T, Xu Z, Liu L, Guo Q, Wu H, Liang X, Zhou D, Xiao L, Liu L, Liu Y, Zhu MS, Chen Q, Gan Z
Cell reports 2018 May 1;23(5):1357-1372
Cell reports 2018 May 1;23(5):1357-1372
AIDA Selectively Mediates Downregulation of Fat Synthesis Enzymes by ERAD to Retard Intestinal Fat Absorption and Prevent Obesity.
Luo H, Jiang M, Lian G, Liu Q, Shi M, Li TY, Song L, Ye J, He Y, Yao L, Zhang C, Lin ZZ, Zhang CS, Zhao TJ, Jia WP, Li P, Lin SY, Lin SC
Cell metabolism 2018 Apr 3;27(4):843-853.e6
Cell metabolism 2018 Apr 3;27(4):843-853.e6
Lack of β, β-carotene-9', 10'-oxygenase 2 leads to hepatic mitochondrial dysfunction and cellular oxidative stress in mice.
Wu L, Guo X, Hartson SD, Davis MA, He H, Medeiros DM, Wang W, Clarke SL, Lucas EA, Smith BJ, von Lintig J, Lin D
Molecular nutrition & food research 2017 May;61(5)
Molecular nutrition & food research 2017 May;61(5)
CUE domain-containing protein 2 promotes the Warburg effect and tumorigenesis.
Zhong X, Tian S, Zhang X, Diao X, Dong F, Yang J, Li Z, Sun L, Wang L, He X, Wu G, Hu X, Wang L, Song L, Zhang H, Pan X, Li A, Gao P
EMBO reports 2017 May;18(5):809-825
EMBO reports 2017 May;18(5):809-825
Calcium sensing receptor protects high glucose-induced energy metabolism disorder via blocking gp78-ubiquitin proteasome pathway.
Wang Y, Gao P, Wei C, Li H, Zhang L, Zhao Y, Wu B, Tian Y, Zhang W, Wu L, Wang R, Xu C
Cell death & disease 2017 May 18;8(5):e2799
Cell death & disease 2017 May 18;8(5):e2799
The changes in glucose metabolism and cell proliferation in the kidneys of polycystic kidney disease mini-pig models.
Lian X, Zhao J, Wu X, Zhang Y, Li Q, Lin S, Bai XY, Chen X
Biochemical and biophysical research communications 2017 Jun 24;488(2):374-381
Biochemical and biophysical research communications 2017 Jun 24;488(2):374-381
DJ-1 modulates mitochondrial response to oxidative stress: clues from a novel diagnosis of PARK7.
Di Nottia M, Masciullo M, Verrigni D, Petrillo S, Modoni A, Rizzo V, Di Giuda D, Rizza T, Niceta M, Torraco A, Bianchi M, Santoro M, Bentivoglio AR, Bertini E, Piemonte F, Carrozzo R, Silvestri G
Clinical genetics 2017 Jul;92(1):18-25
Clinical genetics 2017 Jul;92(1):18-25
CYC1 Predicts Poor Prognosis in Patients with Breast Cancer.
Han Y, Sun S, Zhao M, Zhang Z, Gong S, Gao P, Liu J, Zhou J, Ma D, Gao Q, Wu P
Disease markers 2016;2016:3528064
Disease markers 2016;2016:3528064
Oral quercetin administration transiently protects respiratory function in dystrophin-deficient mice.
Selsby JT, Ballmann CG, Spaulding HR, Ross JW, Quindry JC
The Journal of physiology 2016 Oct 15;594(20):6037-6053
The Journal of physiology 2016 Oct 15;594(20):6037-6053
Mic60/Mitofilin determines MICOS assembly essential for mitochondrial dynamics and mtDNA nucleoid organization.
Li H, Ruan Y, Zhang K, Jian F, Hu C, Miao L, Gong L, Sun L, Zhang X, Chen S, Chen H, Liu D, Song Z
Cell death and differentiation 2016 Mar;23(3):380-92
Cell death and differentiation 2016 Mar;23(3):380-92
COA7 (C1orf163/RESA1) mutations associated with mitochondrial leukoencephalopathy and cytochrome c oxidase deficiency.
Martinez Lyons A, Ardissone A, Reyes A, Robinson AJ, Moroni I, Ghezzi D, Fernandez-Vizarra E, Zeviani M
Journal of medical genetics 2016 Dec;53(12):846-849
Journal of medical genetics 2016 Dec;53(12):846-849
Exercise Inducible Lactate Dehydrogenase B Regulates Mitochondrial Function in Skeletal Muscle.
Liang X, Liu L, Fu T, Zhou Q, Zhou D, Xiao L, Liu J, Kong Y, Xie H, Yi F, Lai L, Vega RB, Kelly DP, Smith SR, Gan Z
The Journal of biological chemistry 2016 Dec 2;291(49):25306-25318
The Journal of biological chemistry 2016 Dec 2;291(49):25306-25318
EglN2 associates with the NRF1-PGC1α complex and controls mitochondrial function in breast cancer.
Zhang J, Wang C, Chen X, Takada M, Fan C, Zheng X, Wen H, Liu Y, Wang C, Pestell RG, Aird KM, Kaelin WG Jr, Liu XS, Zhang Q
The EMBO journal 2015 Dec 2;34(23):2953-70
The EMBO journal 2015 Dec 2;34(23):2953-70
Lin28/let-7 axis regulates aerobic glycolysis and cancer progression via PDK1.
Ma X, Li C, Sun L, Huang D, Li T, He X, Wu G, Yang Z, Zhong X, Song L, Gao P, Zhang H
Nature communications 2014 Oct 10;5:5212
Nature communications 2014 Oct 10;5:5212
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 14865-1-AP(SDHA antibody) at dilution of 1:800
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The SDHA antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SDHA. This antibody recognizes human,mouse,rat antigen. The SDHA antibody has been validated for the following applications: ELISA, WB, IHC analysis.
