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- References [6]
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- Product number
- 15206-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15206-1-AP, RRID:AB_2246413
- Product name
- CRACR2A antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CRACR2A antibody (Cat. #15206-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB, ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Rab46: a novel player in mast cell function.
Affinity-based proteomics reveals novel binding partners for Rab46 in endothelial cells.
Biallelic mutations in calcium release activated channel regulator 2A (CRACR2A) cause a primary immunodeficiency disorder.
Rab46 integrates Ca(2+) and histamine signaling to regulate selective cargo release from Weibel-Palade bodies.
CRACR2A-Mediated TCR Signaling Promotes Local Effector Th1 and Th17 Responses.
Expression of a long variant of CRACR2A that belongs to the Rab GTPase protein family in endothelial cells.
Pedicini L, Smith J, Savic S, McKeown L
Discovery immunology 2024;3(1):kyad028
Discovery immunology 2024;3(1):kyad028
Affinity-based proteomics reveals novel binding partners for Rab46 in endothelial cells.
Pedicini L, Wiktor SD, Simmons KJ, Money A, McKeown L
Scientific reports 2021 Feb 18;11(1):4054
Scientific reports 2021 Feb 18;11(1):4054
Biallelic mutations in calcium release activated channel regulator 2A (CRACR2A) cause a primary immunodeficiency disorder.
Wu B, Rice L, Shrimpton J, Lawless D, Walker K, Carter C, McKeown L, Anwar R, Doody GM, Srikanth S, Gwack Y, Savic S
eLife 2021 Dec 15;10
eLife 2021 Dec 15;10
Rab46 integrates Ca(2+) and histamine signaling to regulate selective cargo release from Weibel-Palade bodies.
Miteva KT, Pedicini L, Wilson LA, Jayasinghe I, Slip RG, Marszalek K, Gaunt HJ, Bartoli F, Deivasigamani S, Sobradillo D, Beech DJ, McKeown L
The Journal of cell biology 2019 Jul 1;218(7):2232-2246
The Journal of cell biology 2019 Jul 1;218(7):2232-2246
CRACR2A-Mediated TCR Signaling Promotes Local Effector Th1 and Th17 Responses.
Woo JS, Srikanth S, Kim KD, Elsaesser H, Lu J, Pellegrini M, Brooks DG, Sun Z, Gwack Y
Journal of immunology (Baltimore, Md. : 1950) 2018 Aug 15;201(4):1174-1185
Journal of immunology (Baltimore, Md. : 1950) 2018 Aug 15;201(4):1174-1185
Expression of a long variant of CRACR2A that belongs to the Rab GTPase protein family in endothelial cells.
Wilson LA, McKeown L, Tumova S, Li J, Beech DJ
Biochemical and biophysical research communications 2015 Jan 2;456(1):398-402
Biochemical and biophysical research communications 2015 Jan 2;456(1):398-402
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The EFCAB4B antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human EFCAB4B. This antibody recognizes human antigen. The EFCAB4B antibody has been validated for the following applications: ELISA, WB analysis.
