CABT-B9201
antibody from Creative Diagnostics
Targeting: DTNA
D18S892E, DRP3, DTN, DTN-1, DTN-2, DTN-3
Antibody data
- Antibody Data
- Antigen structure
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- Validations [0]
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- Product number
- CABT-B9201 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Mouse anti-Mouse Dystrobrevin monoclonal antibody, clone 34
- Antibody type
- Monoclonal
- Description
- Acetylcholine receptor clustering is considered an early event and a marker for synaptogenesis between a motor neuron and a muscle fiber. This process is mediated by the extracellular protein Agrin which binds to Ï« and ÉÇ Dystroglycan, previously discovered as Dystrobrevin- associated proteins. Dystrobrevin binds to the actin cytoskeleton by its N-terminal domain, thus providing the link between the actin cytoskeleton and receptor clustering. In Torpedo electric organ, Dystrobrevin is a prominent phosphotyrosine-containing protein. Murine Dystrobrevins comprise a family of four related proteins (1-4) with similar function, generated by alternative splicing. Dystrobrevin-1 is 688 amino acids and has an apparent mobility of 87kDa. Dystrobrevin-2 shares almost identical sequence with Dystrobrevin-1 in the first 500 amino acids and has an apparent mobility of 59kDa.
- Reactivity
- Mouse, Rat, Rabbit
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 34
- Vial size
- 50 _g
- Concentration
- 250 Ã×g/ml
- Storage
- Store undiluted at -20°C.
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