16714-1-AP

antibody from Proteintech Group

Targeting: PSPC1 FLJ10955, PSP1

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Immunocytochemistry (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Antibody Data

Product number

16714-1-AP

Provider

Proteintech Group

Product name

PSPC1 antibody

Antibody type

Polyclonal

Description

PSPC1 antibody (Cat. #16714-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IP, WB, ELISA.

Reactivity

Human, Mouse, Rat

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

M(6)A-METTL3-dependent nuclear PANC754/PSPC1/H3K4me1 repression complex regulate immune evasive LGALS7 signal to enhance immunotherapy against colorectal cancer.

Zhang J, Cao G, Li F, Tang S, Wu C, Jiang M, Ye J, Ju S, Qian F, Ding W
Cell death & disease 2025 Jul 9;16(1):506

---

Proline exacerbates hepatic gluconeogenesis via paraspeckle-dependent mRNA retention.

Zhao Y, Chai X, Peng J, Zhu Y, Dong R, He J, Xia L, Liu S, Chen J, Xu Z, Luo C, Sheng J
Nature metabolism 2025 Feb;7(2):367-382

---

PSPC1-SMAD3 axis regulates iron-induced beiging of adipocytes in white adipose tissue.

Peng XM, He R, Wang HY, Liu JD, Xie YY, Wang ZH, Deng HY, Wang WS, Zhu ZZ, Ge J, Liu YL, Gao RH, Yang M, Li DP, Kang QQ, Pan RP, Chen Y
Cell communication and signaling : CCS 2025 Dec 4;24(1):12

---

Capture of RNA-binding proteins across mouse tissues using HARD-AP.

Ren Y, Liao H, Yan J, Lu H, Mao X, Wang C, Li YF, Liu Y, Chen C, Chen L, Wang X, Zhou KY, Liu HM, Liu Y, Hua YM, Yu L, Xue Z
Nature communications 2024 Sep 28;15(1):8421

---

Virus-modified paraspeckle-like condensates are hubs for viral RNA processing and their formation drives genomic instability.

Harper KL, Harrington EM, Hayward C, Anene CA, Wongwiwat W, White RE, Whitehouse A
Nature communications 2024 Nov 26;15(1):10240

---

SKP2 promotes the metastasis of pancreatic ductal adenocarcinoma by suppressing TRIM21-mediated PSPC1 degradation.

Yuan J, Zhu Z, Zhang P, Ashrafizadeh M, Abd El-Aty AM, Hacımüftüoğlu A, Linnebacher CS, Linnebacher M, Sethi G, Gong P, Zhang X
Cancer letters 2024 Apr 10;587:216733

---

Cell membrane-camouflaged bufalin targets NOD2 and overcomes multidrug resistance in pancreatic cancer.

Zhang W, Fan Y, Zhang J, Shi D, Yuan J, Ashrafizadeh M, Li W, Hu M, Abd El-Aty AM, Hacimuftuoglu A, Linnebacher M, Cheng Y, Li W, Fang S, Gong P, Zhang X
Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy 2023 Nov;71:101005

---

K235 acetylation couples with PSPC1 to regulate the m(6)A demethylation activity of ALKBH5 and tumorigenesis.

Zhang XL, Chen XH, Xu B, Chen M, Zhu S, Meng N, Wang JZ, Zhu H, Chen D, Liu JB, Yan GR
Nature communications 2023 Jun 27;14(1):3815

---

The KDET Motif in the Intracellular Domain of the Cell Adhesion Molecule L1 Interacts with Several Nuclear, Cytoplasmic, and Mitochondrial Proteins Essential for Neuronal Functions.

Kleene R, Loers G, Schachner M
International journal of molecular sciences 2023 Jan 4;24(2)

---

The Interactions of the 70 kDa Fragment of Cell Adhesion Molecule L1 with Topoisomerase 1, Peroxisome Proliferator-Activated Receptor γ and NADH Dehydrogenase (Ubiquinone) Flavoprotein 2 Are Involved in Gene Expression and Neuronal L1-Dependent Functions.

Loers G, Kleene R, Bork U, Schachner M
International journal of molecular sciences 2023 Jan 20;24(3)

---

The disordered C terminus of ALKBH5 promotes phase separation and paraspeckles assembly.

Qin X, Long Y, Bai X, Cao L, Yan H, Zhang K, Wang B, Wu X
The Journal of biological chemistry 2023 Aug;299(8):105071

---

mRNAs are sorted for export or degradation before passing through nuclear speckles.

Fan J, Kuai B, Wang K, Wang L, Wang Y, Wu X, Chi B, Li G, Cheng H
Nucleic acids research 2018 Sep 19;46(16):8404-8416