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- References [21]
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- Product number
- 11255-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11255-1-AP, RRID:AB_2300786
- Product name
- RAD51AP1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RAD51AP1 antibody (Cat. #11255-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Phosphoregulation of RAD51AP1 function in homology-directed repair.
DLGAP5 protects glioblastoma cells against DNA damage through E2F1-transcripted RAD51AP1.
Phosphoregulation of RAD51AP1 function in homology-directed repair.
Injectable PROTAC-loaded hydrogel remodels the tumor microenvironment to potentiate radio-immunotherapy.
TSPAN7 inhibits pancreatic cancer progression by suppressing DNA double-strand break repair and enhances sensitivity to immunochemotherapy.
TERRA R-loops trigger a switch in telomere maintenance towards break-induced replication and PRIMPOL-dependent repair.
Epigenetically elevated RAD51AP1 regulates the RAD51-UAF1 complex contributing to temozolomide resistance in EGFRvIII glioblastoma.
PRMT1 inhibition perturbs RNA metabolism and induces DNA damage in clear cell renal cell carcinoma.
Pre-rRNA facilitates the recruitment of RAD51AP1 to DNA double-strand breaks.
TERRA-LSD1 phase separation promotes R-loop formation for telomere maintenance in ALT cancer cells.
RRM1 promotes homologous recombination and radio/chemo-sensitivity via enhancing USP11 and E2F1-mediated RAD51AP1 transcription.
Extrachromosomal Telomeres Derived from Excessive Strand Displacements.
The gene RAD51AP1 promotes the progression of pancreatic cancer via the PI3K/Akt/NF-κB signaling pathway.
SOSSB1 and SOSSB2 mutually regulate protein stability through competitive binding of SOSSA.
Systematic pan-cancer analysis showed that RAD51AP1 was associated with immune microenvironment, tumor stemness, and prognosis.
METTL3 antagonizes 5‑FU chemotherapy and confers drug resistance in colorectal carcinoma.
Dual Inhibition of CDK12/CDK13 Targets Both Tumor and Immune Cells in Ovarian Cancer.
TERRA and RAD51AP1 promote alternative lengthening of telomeres through an R- to D-loop switch.
RNA transcripts stimulate homologous recombination by forming DR-loops.
The transcriptional regulator Zfat is essential for maintenance and differentiation of the adipocytes.
BRD4 inhibition sensitizes cervical cancer to radiotherapy by attenuating DNA repair.
Sharma N, Uhrig ME, Kwon Y, Sung P, Wiese C
The Journal of biological chemistry 2026 Mar;302(3):111149
The Journal of biological chemistry 2026 Mar;302(3):111149
DLGAP5 protects glioblastoma cells against DNA damage through E2F1-transcripted RAD51AP1.
Liu Y, Chen R, Liu G, Chen J, Zhou J, Chen Y, Li Z, Li Y, Deng L, Cui H
Biochimica et biophysica acta. Molecular basis of disease 2026 Apr 17;1872(6):168265
Biochimica et biophysica acta. Molecular basis of disease 2026 Apr 17;1872(6):168265
Phosphoregulation of RAD51AP1 function in homology-directed repair.
Sharma N, Uhrig M, Kwon Y, Sung P, Wiese C
bioRxiv : the preprint server for biology 2025 Sep 10;
bioRxiv : the preprint server for biology 2025 Sep 10;
Injectable PROTAC-loaded hydrogel remodels the tumor microenvironment to potentiate radio-immunotherapy.
Zhao W, Xu X, An S, Wu J, Wang H, Luo J, Yuan Y, Li L
Journal of controlled release : official journal of the Controlled Release Society 2025 Nov 10;387:114200
Journal of controlled release : official journal of the Controlled Release Society 2025 Nov 10;387:114200
TSPAN7 inhibits pancreatic cancer progression by suppressing DNA double-strand break repair and enhances sensitivity to immunochemotherapy.
Lin H, Zhou J, Li Y, Luo L, Zeng Y, Liang X, Yu J, Ye C, Yang P, Lin Y, Li Y, Zeng L
Biochemical pharmacology 2025 Jul 30;242(Pt 1):117199
Biochemical pharmacology 2025 Jul 30;242(Pt 1):117199
TERRA R-loops trigger a switch in telomere maintenance towards break-induced replication and PRIMPOL-dependent repair.
In S, Renck Nunes P, Valador Fernandes R, Lingner J
The EMBO journal 2025 Aug;44(16):4525-4551
The EMBO journal 2025 Aug;44(16):4525-4551
Epigenetically elevated RAD51AP1 regulates the RAD51-UAF1 complex contributing to temozolomide resistance in EGFRvIII glioblastoma.
Chang Y, Yang J, Li Z, Zhu X, Jiang T, Wang Q, Yu M, Han B, Liu X
Chinese medical journal 2025 Apr 10;
Chinese medical journal 2025 Apr 10;
PRMT1 inhibition perturbs RNA metabolism and induces DNA damage in clear cell renal cell carcinoma.
Walton J, Ng ASN, Arevalo K, Apostoli A, Meens J, Karamboulas C, St-Germain J, Prinos P, Dmytryshyn J, Chen E, Arrowsmith CH, Raught B, Ailles L
Nature communications 2024 Sep 19;15(1):8232
Nature communications 2024 Sep 19;15(1):8232
Pre-rRNA facilitates the recruitment of RAD51AP1 to DNA double-strand breaks.
Chen L, Gai X, Yu X
The Journal of biological chemistry 2024 Mar;300(3):107115
The Journal of biological chemistry 2024 Mar;300(3):107115
TERRA-LSD1 phase separation promotes R-loop formation for telomere maintenance in ALT cancer cells.
Xu M, Senanayaka D, Zhao R, Chigumira T, Tripathi A, Tones J, Lackner RM, Wondisford AR, Moneysmith LN, Hirschi A, Craig S, Alishiri S, O'Sullivan RJ, Chenoweth DM, Reiter NJ, Zhang H
Nature communications 2024 Mar 9;15(1):2165
Nature communications 2024 Mar 9;15(1):2165
RRM1 promotes homologous recombination and radio/chemo-sensitivity via enhancing USP11 and E2F1-mediated RAD51AP1 transcription.
Yang S, Wang R, Liu L, Xu F, Zhao X, Yao Z, Zhang J, Cheng X, Xu A, Wu L, Zhao G
Cell death discovery 2024 Dec 18;10(1):496
Cell death discovery 2024 Dec 18;10(1):496
Extrachromosomal Telomeres Derived from Excessive Strand Displacements.
Lee J, Lee J, Sohn EJ, Taglialatela A, O'Sullivan RJ, Ciccia A, Min J
bioRxiv : the preprint server for biology 2023 Oct 23;
bioRxiv : the preprint server for biology 2023 Oct 23;
The gene RAD51AP1 promotes the progression of pancreatic cancer via the PI3K/Akt/NF-κB signaling pathway.
Wang Y, Li Y, Ran C, Le W, Dong J, Wang X, Chen B, Jiang X
Neoplasma 2023 Dec;70(6):722-732
Neoplasma 2023 Dec;70(6):722-732
SOSSB1 and SOSSB2 mutually regulate protein stability through competitive binding of SOSSA.
Zhang Q, Hao R, Chen H, Zhou G
Cell death discovery 2023 Aug 28;9(1):319
Cell death discovery 2023 Aug 28;9(1):319
Systematic pan-cancer analysis showed that RAD51AP1 was associated with immune microenvironment, tumor stemness, and prognosis.
Liu R, Zhu G, Li M, Cao P, Li X, Zhang X, Huang H, Song Z, Chen J
Frontiers in genetics 2022;13:971033
Frontiers in genetics 2022;13:971033
METTL3 antagonizes 5‑FU chemotherapy and confers drug resistance in colorectal carcinoma.
Li M, Xia M, Zhang Z, Tan Y, Li E, Guo Z, Fang M, Zhu Y, Hu Z
International journal of oncology 2022 Sep;61(3)
International journal of oncology 2022 Sep;61(3)
Dual Inhibition of CDK12/CDK13 Targets Both Tumor and Immune Cells in Ovarian Cancer.
Cheng L, Zhou S, Zhou S, Shi K, Cheng Y, Cai MC, Ye K, Lin L, Zhang Z, Jia C, Xiang H, Zang J, Zhang M, Yin X, Li Y, Di W, Zhuang G, Tan L
Cancer research 2022 Oct 4;82(19):3588-3602
Cancer research 2022 Oct 4;82(19):3588-3602
TERRA and RAD51AP1 promote alternative lengthening of telomeres through an R- to D-loop switch.
Yadav T, Zhang JM, Ouyang J, Leung W, Simoneau A, Zou L
Molecular cell 2022 Nov 3;82(21):3985-4000.e4
Molecular cell 2022 Nov 3;82(21):3985-4000.e4
RNA transcripts stimulate homologous recombination by forming DR-loops.
Ouyang J, Yadav T, Zhang JM, Yang H, Rheinbay E, Guo H, Haber DA, Lan L, Zou L
Nature 2021 Jun;594(7862):283-288
Nature 2021 Jun;594(7862):283-288
The transcriptional regulator Zfat is essential for maintenance and differentiation of the adipocytes.
Ishikura S, Nagai M, Tsunoda T, Nishi K, Tanaka Y, Koyanagi M, Shirasawa S
Journal of cellular biochemistry 2021 Jun;122(6):626-638
Journal of cellular biochemistry 2021 Jun;122(6):626-638
BRD4 inhibition sensitizes cervical cancer to radiotherapy by attenuating DNA repair.
Ni M, Li J, Zhao H, Xu F, Cheng J, Yu M, Ke G, Wu X
Oncogene 2021 Apr;40(15):2711-2724
Oncogene 2021 Apr;40(15):2711-2724
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The RAD51AP1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RAD51AP1. This antibody recognizes human antigen. The RAD51AP1 antibody has been validated for the following applications: ELISA, WB analysis.
