Antibody data
- Antibody Data
- Antigen structure
- References [10]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 11255-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11255-1-AP, RRID:AB_2300786
- Product name
- RAD51AP1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated RAD51AP1 antibody (Cat. #11255-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Pre-rRNA facilitates the recruitment of RAD51AP1 to DNA double-strand breaks.
TERRA-LSD1 phase separation promotes R-loop formation for telomere maintenance in ALT cancer cells.
Extrachromosomal Telomeres Derived from Excessive Strand Displacements.
Systematic pan-cancer analysis showed that RAD51AP1 was associated with immune microenvironment, tumor stemness, and prognosis.
METTL3 antagonizes 5‑FU chemotherapy and confers drug resistance in colorectal carcinoma.
Dual Inhibition of CDK12/CDK13 Targets Both Tumor and Immune Cells in Ovarian Cancer.
TERRA and RAD51AP1 promote alternative lengthening of telomeres through an R- to D-loop switch.
RNA transcripts stimulate homologous recombination by forming DR-loops.
The transcriptional regulator Zfat is essential for maintenance and differentiation of the adipocytes.
BRD4 inhibition sensitizes cervical cancer to radiotherapy by attenuating DNA repair.
Chen L, Gai X, Yu X
The Journal of biological chemistry 2024 Mar;300(3):107115
The Journal of biological chemistry 2024 Mar;300(3):107115
TERRA-LSD1 phase separation promotes R-loop formation for telomere maintenance in ALT cancer cells.
Xu M, Senanayaka D, Zhao R, Chigumira T, Tripathi A, Tones J, Lackner RM, Wondisford AR, Moneysmith LN, Hirschi A, Craig S, Alishiri S, O'Sullivan RJ, Chenoweth DM, Reiter NJ, Zhang H
Nature communications 2024 Mar 9;15(1):2165
Nature communications 2024 Mar 9;15(1):2165
Extrachromosomal Telomeres Derived from Excessive Strand Displacements.
Lee J, Lee J, Sohn EJ, Taglialatela A, O'Sullivan RJ, Ciccia A, Min J
bioRxiv : the preprint server for biology 2023 Oct 23;
bioRxiv : the preprint server for biology 2023 Oct 23;
Systematic pan-cancer analysis showed that RAD51AP1 was associated with immune microenvironment, tumor stemness, and prognosis.
Liu R, Zhu G, Li M, Cao P, Li X, Zhang X, Huang H, Song Z, Chen J
Frontiers in genetics 2022;13:971033
Frontiers in genetics 2022;13:971033
METTL3 antagonizes 5‑FU chemotherapy and confers drug resistance in colorectal carcinoma.
Li M, Xia M, Zhang Z, Tan Y, Li E, Guo Z, Fang M, Zhu Y, Hu Z
International journal of oncology 2022 Sep;61(3)
International journal of oncology 2022 Sep;61(3)
Dual Inhibition of CDK12/CDK13 Targets Both Tumor and Immune Cells in Ovarian Cancer.
Cheng L, Zhou S, Zhou S, Shi K, Cheng Y, Cai MC, Ye K, Lin L, Zhang Z, Jia C, Xiang H, Zang J, Zhang M, Yin X, Li Y, Di W, Zhuang G, Tan L
Cancer research 2022 Oct 4;82(19):3588-3602
Cancer research 2022 Oct 4;82(19):3588-3602
TERRA and RAD51AP1 promote alternative lengthening of telomeres through an R- to D-loop switch.
Yadav T, Zhang JM, Ouyang J, Leung W, Simoneau A, Zou L
Molecular cell 2022 Nov 3;82(21):3985-4000.e4
Molecular cell 2022 Nov 3;82(21):3985-4000.e4
RNA transcripts stimulate homologous recombination by forming DR-loops.
Ouyang J, Yadav T, Zhang JM, Yang H, Rheinbay E, Guo H, Haber DA, Lan L, Zou L
Nature 2021 Jun;594(7862):283-288
Nature 2021 Jun;594(7862):283-288
The transcriptional regulator Zfat is essential for maintenance and differentiation of the adipocytes.
Ishikura S, Nagai M, Tsunoda T, Nishi K, Tanaka Y, Koyanagi M, Shirasawa S
Journal of cellular biochemistry 2021 Jun;122(6):626-638
Journal of cellular biochemistry 2021 Jun;122(6):626-638
BRD4 inhibition sensitizes cervical cancer to radiotherapy by attenuating DNA repair.
Ni M, Li J, Zhao H, Xu F, Cheng J, Yu M, Ke G, Wu X
Oncogene 2021 Apr;40(15):2711-2724
Oncogene 2021 Apr;40(15):2711-2724
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The RAD51AP1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human RAD51AP1. This antibody recognizes human antigen. The RAD51AP1 antibody has been validated for the following applications: ELISA, WB analysis.