Antibody data
- Antibody Data
- Antigen structure
- References [1]
- Comments [0]
- Validations
- Flow cytometry [1]
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Validation data
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- Product number
- 307206 - Provider product page
- Provider
- BioLegend
- Proper citation
- BioLegend Cat#307206, RRID:AB_2287472
- Product name
- PE anti-human CD261 (DR4, TRAIL-R1)
- Antibody type
- Monoclonal
- Antigen
- Extracellular domain of DR4-human IgG1 Fc fusion protein
- Description
- DR4 is 56 kD member 10A of the TNFR superfamily (TNFRSF10A), also known as TRAIL-R1, Apo-2, and CD261. It is expressed at low levels by activated T cells and some tumors. After TRAIL engagement, DR4 (TRAIL-R1), through activation of NF-κB, induces apoptosis in the TRAIL ligated cell.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Yellow dye
- Isotype
- IgG
- Vial size
- 100 tests
- Storage
- The antibody solution should be stored undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Submitted references Primitive quiescent CD34+ cells in chronic myeloid leukemia are targeted by in vitro expanded natural killer cells, which are functionally enhanced by bortezomib.
Yong AS, Keyvanfar K, Hensel N, Eniafe R, Savani BN, Berg M, Lundqvist A, Adams S, Sloand EM, Goldman JM, Childs R, Barrett AJ
Blood 2009 Jan 22;113(4):875-82
Blood 2009 Jan 22;113(4):875-82
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Supportive validation
- Submitted by
- BioLegend (provider)
- Main image
- Experimental details
- Human DR4 transfected cells stained with DJR1 PE
- Conjugate
- Yellow dye