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- Antigen structure
- References [17]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 13907-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13907-1-AP, RRID:AB_2273887
- Product name
- AKAP3 antibody
- Antibody type
- Polyclonal
- Description
- AKAP3 antibody (Cat. #13907-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Coiled-coil domain-containing 38 is required for acrosome biogenesis and fibrous sheath assembly in mice.
CCDC183 is essential for cytoplasmic invagination around the flagellum during spermiogenesis and male fertility.
STK33 Phosphorylates Fibrous Sheath Protein AKAP3/4 to Regulate Sperm Flagella Assembly in Spermiogenesis.
Homozygous variants in AKAP3 induce asthenoteratozoospermia and male infertility.
LRRC23 truncation impairs radial spoke 3 head assembly and sperm motility underlying male infertility.
IRGC1, a testis-enriched immunity related GTPase, is important for fibrous sheath integrity and sperm motility in mice.
The cancer-testis antigen a-kinase anchor protein 3 facilitates breast cancer progression via activation of the PTEN/PI3K/AKT/mTOR signaling.
Comparative Proteomics and Phosphoproteomics Analysis Reveal the Possible Breed Difference in Yorkshire and Duroc Boar Spermatozoa.
SPATA33 localizes calcineurin to the mitochondria and regulates sperm motility in mice.
Fluoride exposure alters the ultra-structure of sperm flagellum via reducing key protein expressions in testis.
CFAP43 modulates ciliary beating in mouse and Xenopus.
The FOXJ1 target Cfap206 is required for sperm motility, mucociliary clearance of the airways and brain development.
Loss-of-function mutations in QRICH2 cause male infertility with multiple morphological abnormalities of the sperm flagella.
Biallelic mutations in PMFBP1 cause acephalic spermatozoa.
FSIP1 binds HER2 directly to regulate breast cancer growth and invasiveness.
CABYR is essential for fibrous sheath integrity and progressive motility in mouse spermatozoa.
Interactome of the negative regulator of nuclear import BRCA1-binding protein 2.
Wang Y, Huang X, Sun G, Chen J, Wu B, Luo J, Tang S, Dai P, Zhang F, Li J, Wang L
Journal of genetics and genomics = Yi chuan xue bao 2024 Apr;51(4):407-418
Journal of genetics and genomics = Yi chuan xue bao 2024 Apr;51(4):407-418
CCDC183 is essential for cytoplasmic invagination around the flagellum during spermiogenesis and male fertility.
Shimada K, Ikawa M
Development (Cambridge, England) 2023 Nov 1;150(21)
Development (Cambridge, England) 2023 Nov 1;150(21)
STK33 Phosphorylates Fibrous Sheath Protein AKAP3/4 to Regulate Sperm Flagella Assembly in Spermiogenesis.
Yu W, Li Y, Chen H, Cui Y, Situ C, Yao L, Zhang X, Lu S, Liu L, Li L, Ren J, Guo Y, Huo Z, Chen Y, Li H, Jiang T, Gu Y, Wang C, Zhu T, Li Y, Hu Z, Guo X
Molecular & cellular proteomics : MCP 2023 Jun;22(6):100564
Molecular & cellular proteomics : MCP 2023 Jun;22(6):100564
Homozygous variants in AKAP3 induce asthenoteratozoospermia and male infertility.
Liu C, Shen Y, Tang S, Wang J, Zhou Y, Tian S, Wu H, Cong J, He X, Jin L, Cao Y, Yang Y, Zhang F
Journal of medical genetics 2023 Feb;60(2):137-143
Journal of medical genetics 2023 Feb;60(2):137-143
LRRC23 truncation impairs radial spoke 3 head assembly and sperm motility underlying male infertility.
Hwang JY, Chai P, Nawaz S, Choi J, Lopez-Giraldez F, Hussain S, Bilguvar K, Mane S, Lifton RP, Ahmad W, Zhang K, Chung JJ
eLife 2023 Dec 13;12
eLife 2023 Dec 13;12
IRGC1, a testis-enriched immunity related GTPase, is important for fibrous sheath integrity and sperm motility in mice.
Kaneda Y, Miyata H, Shimada K, Oyama Y, Iida-Norita R, Ikawa M
Developmental biology 2022 Aug;488:104-113
Developmental biology 2022 Aug;488:104-113
The cancer-testis antigen a-kinase anchor protein 3 facilitates breast cancer progression via activation of the PTEN/PI3K/AKT/mTOR signaling.
Zhan CH, Ding DS, Zhang W, Wang HL, Mao ZY, Liu GJ
Bioengineered 2022 Apr;13(4):8478-8489
Bioengineered 2022 Apr;13(4):8478-8489
Comparative Proteomics and Phosphoproteomics Analysis Reveal the Possible Breed Difference in Yorkshire and Duroc Boar Spermatozoa.
Xu Y, Han Q, Ma C, Wang Y, Zhang P, Li C, Cheng X, Xu H
Frontiers in cell and developmental biology 2021;9:652809
Frontiers in cell and developmental biology 2021;9:652809
SPATA33 localizes calcineurin to the mitochondria and regulates sperm motility in mice.
Miyata H, Oura S, Morohoshi A, Shimada K, Mashiko D, Oyama Y, Kaneda Y, Matsumura T, Abbasi F, Ikawa M
Proceedings of the National Academy of Sciences of the United States of America 2021 Aug 31;118(35)
Proceedings of the National Academy of Sciences of the United States of America 2021 Aug 31;118(35)
Fluoride exposure alters the ultra-structure of sperm flagellum via reducing key protein expressions in testis.
Liang C, He Y, Liu Y, Gao Y, Han Y, Li X, Zhao Y, Wang J, Zhang J
Chemosphere 2020 May;246:125772
Chemosphere 2020 May;246:125772
CFAP43 modulates ciliary beating in mouse and Xenopus.
Rachev E, Schuster-Gossler K, Fuhl F, Ott T, Tveriakhina L, Beckers A, Hegermann J, Boldt K, Mai M, Kremmer E, Ueffing M, Blum M, Gossler A
Developmental biology 2020 Mar 15;459(2):109-125
Developmental biology 2020 Mar 15;459(2):109-125
The FOXJ1 target Cfap206 is required for sperm motility, mucociliary clearance of the airways and brain development.
Beckers A, Adis C, Schuster-Gossler K, Tveriakhina L, Ott T, Fuhl F, Hegermann J, Boldt K, Serth K, Rachev E, Alten L, Kremmer E, Ueffing M, Blum M, Gossler A
Development (Cambridge, England) 2020 Jun 15;147(21)
Development (Cambridge, England) 2020 Jun 15;147(21)
Loss-of-function mutations in QRICH2 cause male infertility with multiple morphological abnormalities of the sperm flagella.
Shen Y, Zhang F, Li F, Jiang X, Yang Y, Li X, Li W, Wang X, Cheng J, Liu M, Zhang X, Yuan G, Pei X, Cai K, Hu F, Sun J, Yan L, Tang L, Jiang C, Tu W, Xu J, Wu H, Kong W, Li S, Wang K, Sheng K, Zhao X, Yue H, Yang X, Xu W
Nature communications 2019 Jan 25;10(1):433
Nature communications 2019 Jan 25;10(1):433
Biallelic mutations in PMFBP1 cause acephalic spermatozoa.
Sha YW, Wang X, Xu X, Ding L, Liu WS, Li P, Su ZY, Chen J, Mei LB, Zheng LK, Wang HL, Kong SB, You M, Wu JF
Clinical genetics 2019 Feb;95(2):277-286
Clinical genetics 2019 Feb;95(2):277-286
FSIP1 binds HER2 directly to regulate breast cancer growth and invasiveness.
Liu T, Zhang H, Sun L, Zhao D, Liu P, Yan M, Zaidi N, Izadmehr S, Gupta A, Abu-Amer W, Luo M, Yang J, Ou X, Wang Y, Bai X, Wang Y, New MI, Zaidi M, Yuen T, Liu C
Proceedings of the National Academy of Sciences of the United States of America 2017 Jul 18;114(29):7683-7688
Proceedings of the National Academy of Sciences of the United States of America 2017 Jul 18;114(29):7683-7688
CABYR is essential for fibrous sheath integrity and progressive motility in mouse spermatozoa.
Young SA, Miyata H, Satouh Y, Aitken RJ, Baker MA, Ikawa M
Journal of cell science 2016 Dec 1;129(23):4379-4387
Journal of cell science 2016 Dec 1;129(23):4379-4387
Interactome of the negative regulator of nuclear import BRCA1-binding protein 2.
Fatima S, Wagstaff KM, Loveland KL, Jans DA
Scientific reports 2015 Mar 30;5:9459
Scientific reports 2015 Mar 30;5:9459
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse testis tissue were subjected to SDS PAGE followed by western blot with 13907-1-AP(AKAP3 antibody) at dilution of 1:5000
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human testis using 13907-1-AP(AKAP3 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The AKAP3 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human AKAP3. This antibody recognizes human,mouse,rat antigen. The AKAP3 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
