HPA001240

antibody from Atlas Antibodies

Targeting: MPST MST, TST2, TUM1

Western blot (Data presented on provider website)

Immunocytochemistry (Supportive data in Antibodypedia)

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA001240

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA001240, RRID:AB_1079408

Product name

Anti-MPST

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human MPST, Gene description: mercaptopyruvate sulfurtransferase, Alternative Gene Names: MST, TST2, Validated applications: WB, IHC, ICC, Uniprot ID: P25325, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.1 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

Loss of cardiac mitochondrial complex I persulfidation impairs NAD+ homeostasis in aging

Drekolia M, Karantanou C, Wittig I, Li Y, Fuhrmann D, Brüne B, Katsouda A, Hu J, Papapetropoulos A, Bibli S
Redox Biology 2024;69

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Garlic oil supplementation blocks inflammatory pyroptosis-related acute lung injury by suppressing the NF-κB/NLRP3 signaling pathway via H2S generation

Dilxat T, Shi Q, Chen X, Liu X
Aging 2024

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CTH/MPST double ablation results in enhanced vasorelaxation and reduced blood pressure via upregulation of the eNOS/sGC pathway

Katsouda A, Markou M, Zampas P, Varela A, Davos C, Vellecco V, Cirino G, Bucci M, Papapetropoulos A
Frontiers in Pharmacology 2023;14

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Proteome Profiling of the Dystrophic mdx Mice Diaphragm

Mucha O, Myszka M, Podkalicka P, Świderska B, Malinowska A, Dulak J, Łoboda A
Biomolecules 2023;13(11):1648

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MPST sulfurtransferase maintains mitochondrial protein import and cellular bioenergetics to attenuate obesity

Katsouda A, Valakos D, Dionellis V, Bibli S, Akoumianakis I, Karaliota S, Zuhra K, Fleming I, Nagahara N, Havaki S, Gorgoulis V, Thanos D, Antoniades C, Szabo C, Papapetropoulos A
Journal of Experimental Medicine 2022;219(7)

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D-Cysteine Activates Chaperone-Mediated Autophagy in Cerebellar Purkinje Cells via the Generation of Hydrogen Sulfide and Nrf2 Activation

Ueda E, Ohta T, Konno A, Hirai H, Kurauchi Y, Katsuki H, Seki T
Cells 2022;11(7):1230

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Differential effects of subchronic acrylonitrile exposure on hydrogen sulfide levels in rat blood, brain, and liver

Yang B, Yin C, Zhang Y, Xing G, Wang S, Li F, Aschner M, Lu R
Toxicology Research 2022;11(2):374-384

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Cysteine Boosts Fitness Under Hypoxia-Mimicked Conditions in Ovarian Cancer by Metabolic Reprogramming

Nunes S, Ramos C, Santos I, Mendes C, Silva F, Vicente J, Pereira S, Félix A, Gonçalves L, Serpa J
Frontiers in Cell and Developmental Biology 2021;9

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Intracellular H2S production is an autophagy-dependent adaptive response to DNA damage

Jiang X, MacArthur M, Treviño-Villarreal J, Kip P, Ozaki C, Mitchell S, Mitchell J
Cell Chemical Biology 2021;28(12):1669-1678.e5

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Sulfide catabolism ameliorates hypoxic brain injury

Marutani E, Morita M, Hirai S, Kai S, Grange R, Miyazaki Y, Nagashima F, Traeger L, Magliocca A, Ida T, Matsunaga T, Flicker D, Corman B, Mori N, Yamazaki Y, Batten A, Li R, Tanaka T, Ikeda T, Nakagawa A, Atochin D, Ihara H, Olenchock B, Shen X, Nishida M, Hanaoka K, Kevil C, Xian M, Bloch D, Akaike T, Hindle A, Motohashi H, Ichinose F
Nature Communications 2021;12(1)

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ΔMST and the Regulation of Cardiac CSE and OTR Expression in Trauma and Hemorrhage

Trautwein B, Merz T, Denoix N, Szabo C, Calzia E, Radermacher P, McCook O
Antioxidants 2021;10(2):233

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Coenzyme Q10 modulates sulfide metabolism and links the mitochondrial respiratory chain to pathways associated to one carbon metabolism

González-García P, Hidalgo-Gutiérrez A, Mascaraque C, Barriocanal-Casado E, Bakkali M, Ziosi M, Abdihankyzy U, Sánchez-Hernández S, Escames G, Prokisch H, Martín F, Quinzii C, López L
Human Molecular Genetics 2020;29(19):3296-3311

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Shear stress regulates cystathionine γ lyase expression to preserve endothelial redox balance and reduce membrane lipid peroxidation

Bibli S, Hu J, Leisegang M, Wittig J, Zukunft S, Kapasakalidi A, Fisslthaler B, Tsilimigras D, Zografos G, Filis K, Brandes R, Papapetropoulos A, Sigala F, Fleming I
Redox Biology 2020;28

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Generation and Characterization of a CRISPR/Cas9—Induced 3-mst Deficient Zebrafish

Katsouda A, Peleli M, Asimakopoulou A, Papapetropoulos A, Beis D
Biomolecules 2020;10(2):317

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Hydrogen sulfide-mediated endothelial function and the interaction with eNOS and PDE5A activity in human internal mammary arteries

Yuan C, Hou H, Chen H, Wang J, Wang Z, Chen T, Novakovic A, Marinko M, Yang Q, Liu Z, He G
Journal of International Medical Research 2019;47(8):3778-3791

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Hydrogen sulfide regulation of renal and mesenteric blood flow

Morales-Loredo H, Barrera A, Garcia J, Pace C, Naik J, Gonzalez Bosc L, Kanagy N
American Journal of Physiology-Heart and Circulatory Physiology 2019;317(5):H1157-H1165

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Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration

Zivanovic J, Kouroussis E, Kohl J, Adhikari B, Bursac B, Schott-Roux S, Petrovic D, Miljkovic J, Thomas-Lopez D, Jung Y, Miler M, Mitchell S, Milosevic V, Gomes J, Benhar M, Gonzalez-Zorn B, Ivanovic-Burmazovic I, Torregrossa R, Mitchell J, Whiteman M, Schwarz G, Snyder S, Paul B, Carroll K, Filipovic M
Cell Metabolism 2019;30(6):1152-1170.e13

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3‐Mercaptopyruvate sulfurtransferase supports endothelial cell angiogenesis and bioenergetics

Abdollahi Govar A, Törő G, Szaniszlo P, Pavlidou A, Bibli S, Thanki K, Resto V, Chao C, Hellmich M, Szabo C, Papapetropoulos A, Módis K
British Journal of Pharmacology 2019;177(4):866-883

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Endogenous Hydrogen Sulfide Contributes to Tone Generation in Porcine Lower Esophageal Sphincter Via Na+/Ca2+ Exchanger

Bai X, Ihara E, Hirano K, Tanaka Y, Nakano K, Kita S, Iwamoto T, Ogino H, Hirano M, Oda Y, Nakamura K, Ogawa Y
Cellular and Molecular Gastroenterology and Hepatology 2018;5(3):209-221

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Hypothalamic-Pituitary Axis Regulates Hydrogen Sulfide Production

Hine C, Kim H, Zhu Y, Harputlugil E, Longchamp A, Matos M, Ramadoss P, Bauerle K, Brace L, Asara J, Ozaki C, Cheng S, Singha S, Ahn K, Kimmelman A, Fisher F, Pissios P, Withers D, Selman C, Wang R, Yen K, Longo V, Cohen P, Bartke A, Kopchick J, Miller R, Hollenberg A, Mitchell J
Cell Metabolism 2017;25(6):1320-1333.e5

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Global Proteome Changes in the Rat Diaphragm Induced by Endurance Exercise Training

Moran M, Sollanek K, Burniston J, Kavazis A, Morton A, Wiggs M, Ahn B, Smuder A, Powers S
PLOS ONE 2017;12(1):e0171007

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Effect of endotoxemia in mice genetically deficient in cystathionine-γ-lyase, cystathionine-β-synthase or 3-mercaptopyruvate sulfurtransferase

Ahmad A, Gerö D, Olah G, Szabo C
International Journal of Molecular Medicine 2016;38(6):1683-1692

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Hydrogen sulphide‐induced relaxation of porcine peripheral bronchioles

Rashid S, Heer J, Garle M, Alexander S, Roberts R
British Journal of Pharmacology 2013;168(8):1902-1910

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Vascular Endothelium Expresses 3-Mercaptopyruvate Sulfurtransferase and Produces Hydrogen Sulfide

Shibuya N, Mikami Y, Kimura Y, Nagahara N, Kimura H
Journal of Biochemistry 2009;146(5):623-626

Immunocytochemistry

Supportive validation

Submitted by

Atlas Antibodies (provider)

Main image

Experimental details

Immunofluorescent staining of human cell line A-431 shows localization to mitochondria.

Sample type

Human