Antibody data
- Antibody Data
- Antigen structure
- References [24]
- Comments [0]
- Validations
- Immunocytochemistry [1]
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Validation data
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- Product number
- HPA001240 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA001240, RRID:AB_1079408
- Product name
- Anti-MPST
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human MPST, Gene description: mercaptopyruvate sulfurtransferase, Alternative Gene Names: MST, TST2, Validated applications: WB, IHC, ICC, Uniprot ID: P25325, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.1 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Loss of cardiac mitochondrial complex I persulfidation impairs NAD+ homeostasis in aging
Garlic oil supplementation blocks inflammatory pyroptosis-related acute lung injury by suppressing the NF-κB/NLRP3 signaling pathway via H2S generation
CTH/MPST double ablation results in enhanced vasorelaxation and reduced blood pressure via upregulation of the eNOS/sGC pathway
Proteome Profiling of the Dystrophic mdx Mice Diaphragm
MPST sulfurtransferase maintains mitochondrial protein import and cellular bioenergetics to attenuate obesity
D-Cysteine Activates Chaperone-Mediated Autophagy in Cerebellar Purkinje Cells via the Generation of Hydrogen Sulfide and Nrf2 Activation
Differential effects of subchronic acrylonitrile exposure on hydrogen sulfide levels in rat blood, brain, and liver
Cysteine Boosts Fitness Under Hypoxia-Mimicked Conditions in Ovarian Cancer by Metabolic Reprogramming
Intracellular H2S production is an autophagy-dependent adaptive response to DNA damage
Sulfide catabolism ameliorates hypoxic brain injury
ΔMST and the Regulation of Cardiac CSE and OTR Expression in Trauma and Hemorrhage
Coenzyme Q10 modulates sulfide metabolism and links the mitochondrial respiratory chain to pathways associated to one carbon metabolism
Shear stress regulates cystathionine γ lyase expression to preserve endothelial redox balance and reduce membrane lipid peroxidation
Generation and Characterization of a CRISPR/Cas9—Induced 3-mst Deficient Zebrafish
Hydrogen sulfide-mediated endothelial function and the interaction with eNOS and PDE5A activity in human internal mammary arteries
Hydrogen sulfide regulation of renal and mesenteric blood flow
Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration
3‐Mercaptopyruvate sulfurtransferase supports endothelial cell angiogenesis and bioenergetics
Endogenous Hydrogen Sulfide Contributes to Tone Generation in Porcine Lower Esophageal Sphincter Via Na+/Ca2+ Exchanger
Hypothalamic-Pituitary Axis Regulates Hydrogen Sulfide Production
Global Proteome Changes in the Rat Diaphragm Induced by Endurance Exercise Training
Effect of endotoxemia in mice genetically deficient in cystathionine-γ-lyase, cystathionine-β-synthase or 3-mercaptopyruvate sulfurtransferase
Hydrogen sulphide‐induced relaxation of porcine peripheral bronchioles
Vascular Endothelium Expresses 3-Mercaptopyruvate Sulfurtransferase and Produces Hydrogen Sulfide
Drekolia M, Karantanou C, Wittig I, Li Y, Fuhrmann D, Brüne B, Katsouda A, Hu J, Papapetropoulos A, Bibli S
Redox Biology 2024;69
Redox Biology 2024;69
Garlic oil supplementation blocks inflammatory pyroptosis-related acute lung injury by suppressing the NF-κB/NLRP3 signaling pathway via H2S generation
Dilxat T, Shi Q, Chen X, Liu X
Aging 2024
Aging 2024
CTH/MPST double ablation results in enhanced vasorelaxation and reduced blood pressure via upregulation of the eNOS/sGC pathway
Katsouda A, Markou M, Zampas P, Varela A, Davos C, Vellecco V, Cirino G, Bucci M, Papapetropoulos A
Frontiers in Pharmacology 2023;14
Frontiers in Pharmacology 2023;14
Proteome Profiling of the Dystrophic mdx Mice Diaphragm
Mucha O, Myszka M, Podkalicka P, Świderska B, Malinowska A, Dulak J, Łoboda A
Biomolecules 2023;13(11):1648
Biomolecules 2023;13(11):1648
MPST sulfurtransferase maintains mitochondrial protein import and cellular bioenergetics to attenuate obesity
Katsouda A, Valakos D, Dionellis V, Bibli S, Akoumianakis I, Karaliota S, Zuhra K, Fleming I, Nagahara N, Havaki S, Gorgoulis V, Thanos D, Antoniades C, Szabo C, Papapetropoulos A
Journal of Experimental Medicine 2022;219(7)
Journal of Experimental Medicine 2022;219(7)
D-Cysteine Activates Chaperone-Mediated Autophagy in Cerebellar Purkinje Cells via the Generation of Hydrogen Sulfide and Nrf2 Activation
Ueda E, Ohta T, Konno A, Hirai H, Kurauchi Y, Katsuki H, Seki T
Cells 2022;11(7):1230
Cells 2022;11(7):1230
Differential effects of subchronic acrylonitrile exposure on hydrogen sulfide levels in rat blood, brain, and liver
Yang B, Yin C, Zhang Y, Xing G, Wang S, Li F, Aschner M, Lu R
Toxicology Research 2022;11(2):374-384
Toxicology Research 2022;11(2):374-384
Cysteine Boosts Fitness Under Hypoxia-Mimicked Conditions in Ovarian Cancer by Metabolic Reprogramming
Nunes S, Ramos C, Santos I, Mendes C, Silva F, Vicente J, Pereira S, Félix A, Gonçalves L, Serpa J
Frontiers in Cell and Developmental Biology 2021;9
Frontiers in Cell and Developmental Biology 2021;9
Intracellular H2S production is an autophagy-dependent adaptive response to DNA damage
Jiang X, MacArthur M, Treviño-Villarreal J, Kip P, Ozaki C, Mitchell S, Mitchell J
Cell Chemical Biology 2021;28(12):1669-1678.e5
Cell Chemical Biology 2021;28(12):1669-1678.e5
Sulfide catabolism ameliorates hypoxic brain injury
Marutani E, Morita M, Hirai S, Kai S, Grange R, Miyazaki Y, Nagashima F, Traeger L, Magliocca A, Ida T, Matsunaga T, Flicker D, Corman B, Mori N, Yamazaki Y, Batten A, Li R, Tanaka T, Ikeda T, Nakagawa A, Atochin D, Ihara H, Olenchock B, Shen X, Nishida M, Hanaoka K, Kevil C, Xian M, Bloch D, Akaike T, Hindle A, Motohashi H, Ichinose F
Nature Communications 2021;12(1)
Nature Communications 2021;12(1)
ΔMST and the Regulation of Cardiac CSE and OTR Expression in Trauma and Hemorrhage
Trautwein B, Merz T, Denoix N, Szabo C, Calzia E, Radermacher P, McCook O
Antioxidants 2021;10(2):233
Antioxidants 2021;10(2):233
Coenzyme Q10 modulates sulfide metabolism and links the mitochondrial respiratory chain to pathways associated to one carbon metabolism
González-García P, Hidalgo-Gutiérrez A, Mascaraque C, Barriocanal-Casado E, Bakkali M, Ziosi M, Abdihankyzy U, Sánchez-Hernández S, Escames G, Prokisch H, Martín F, Quinzii C, López L
Human Molecular Genetics 2020;29(19):3296-3311
Human Molecular Genetics 2020;29(19):3296-3311
Shear stress regulates cystathionine γ lyase expression to preserve endothelial redox balance and reduce membrane lipid peroxidation
Bibli S, Hu J, Leisegang M, Wittig J, Zukunft S, Kapasakalidi A, Fisslthaler B, Tsilimigras D, Zografos G, Filis K, Brandes R, Papapetropoulos A, Sigala F, Fleming I
Redox Biology 2020;28
Redox Biology 2020;28
Generation and Characterization of a CRISPR/Cas9—Induced 3-mst Deficient Zebrafish
Katsouda A, Peleli M, Asimakopoulou A, Papapetropoulos A, Beis D
Biomolecules 2020;10(2):317
Biomolecules 2020;10(2):317
Hydrogen sulfide-mediated endothelial function and the interaction with eNOS and PDE5A activity in human internal mammary arteries
Yuan C, Hou H, Chen H, Wang J, Wang Z, Chen T, Novakovic A, Marinko M, Yang Q, Liu Z, He G
Journal of International Medical Research 2019;47(8):3778-3791
Journal of International Medical Research 2019;47(8):3778-3791
Hydrogen sulfide regulation of renal and mesenteric blood flow
Morales-Loredo H, Barrera A, Garcia J, Pace C, Naik J, Gonzalez Bosc L, Kanagy N
American Journal of Physiology-Heart and Circulatory Physiology 2019;317(5):H1157-H1165
American Journal of Physiology-Heart and Circulatory Physiology 2019;317(5):H1157-H1165
Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration
Zivanovic J, Kouroussis E, Kohl J, Adhikari B, Bursac B, Schott-Roux S, Petrovic D, Miljkovic J, Thomas-Lopez D, Jung Y, Miler M, Mitchell S, Milosevic V, Gomes J, Benhar M, Gonzalez-Zorn B, Ivanovic-Burmazovic I, Torregrossa R, Mitchell J, Whiteman M, Schwarz G, Snyder S, Paul B, Carroll K, Filipovic M
Cell Metabolism 2019;30(6):1152-1170.e13
Cell Metabolism 2019;30(6):1152-1170.e13
3‐Mercaptopyruvate sulfurtransferase supports endothelial cell angiogenesis and bioenergetics
Abdollahi Govar A, Törő G, Szaniszlo P, Pavlidou A, Bibli S, Thanki K, Resto V, Chao C, Hellmich M, Szabo C, Papapetropoulos A, Módis K
British Journal of Pharmacology 2019;177(4):866-883
British Journal of Pharmacology 2019;177(4):866-883
Endogenous Hydrogen Sulfide Contributes to Tone Generation in Porcine Lower Esophageal Sphincter Via Na+/Ca2+ Exchanger
Bai X, Ihara E, Hirano K, Tanaka Y, Nakano K, Kita S, Iwamoto T, Ogino H, Hirano M, Oda Y, Nakamura K, Ogawa Y
Cellular and Molecular Gastroenterology and Hepatology 2018;5(3):209-221
Cellular and Molecular Gastroenterology and Hepatology 2018;5(3):209-221
Hypothalamic-Pituitary Axis Regulates Hydrogen Sulfide Production
Hine C, Kim H, Zhu Y, Harputlugil E, Longchamp A, Matos M, Ramadoss P, Bauerle K, Brace L, Asara J, Ozaki C, Cheng S, Singha S, Ahn K, Kimmelman A, Fisher F, Pissios P, Withers D, Selman C, Wang R, Yen K, Longo V, Cohen P, Bartke A, Kopchick J, Miller R, Hollenberg A, Mitchell J
Cell Metabolism 2017;25(6):1320-1333.e5
Cell Metabolism 2017;25(6):1320-1333.e5
Global Proteome Changes in the Rat Diaphragm Induced by Endurance Exercise Training
Moran M, Sollanek K, Burniston J, Kavazis A, Morton A, Wiggs M, Ahn B, Smuder A, Powers S
PLOS ONE 2017;12(1):e0171007
PLOS ONE 2017;12(1):e0171007
Effect of endotoxemia in mice genetically deficient in cystathionine-γ-lyase, cystathionine-β-synthase or 3-mercaptopyruvate sulfurtransferase
Ahmad A, Gerö D, Olah G, Szabo C
International Journal of Molecular Medicine 2016;38(6):1683-1692
International Journal of Molecular Medicine 2016;38(6):1683-1692
Hydrogen sulphide‐induced relaxation of porcine peripheral bronchioles
Rashid S, Heer J, Garle M, Alexander S, Roberts R
British Journal of Pharmacology 2013;168(8):1902-1910
British Journal of Pharmacology 2013;168(8):1902-1910
Vascular Endothelium Expresses 3-Mercaptopyruvate Sulfurtransferase and Produces Hydrogen Sulfide
Shibuya N, Mikami Y, Kimura Y, Nagahara N, Kimura H
Journal of Biochemistry 2009;146(5):623-626
Journal of Biochemistry 2009;146(5):623-626
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Main image
- Experimental details
- Immunofluorescent staining of human cell line A-431 shows localization to mitochondria.
- Sample type
- Human