Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Immunohistochemistry [1]
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Validation data
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- Product number
- HPA014975 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA014975, RRID:AB_1857529
- Product name
- Anti-ST6GALNAC1
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human ST6GALNAC1, Gene description: ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 1, Alternative Gene Names: SIAT7A, ST6GalNAcI, Validated applications: IHC, Uniprot ID: Q9NSC7, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.4 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Mucus sialylation determines intestinal host-commensal homeostasis
ST6GALNAC1 plays important roles in enhancing cancer stem phenotypes of colorectal cancer via the Akt pathway.
The androgen receptor controls expression of the cancer-associated sTn antigen and cell adhesion through induction of ST6GalNAc1 in prostate cancer
Yao Y, Kim G, Shafer S, Chen Z, Kubo S, Ji Y, Luo J, Yang W, Perner S, Kanellopoulou C, Park A, Jiang P, Li J, Baris S, Aydiner E, Ertem D, Mulder D, Warner N, Griffiths A, Topf-Olivestone C, Kori M, Werner L, Ouahed J, Field M, Liu C, Schwarz B, Bosio C, Ganesan S, Song J, Urlaub H, Oellerich T, Malaker S, Zheng L, Bertozzi C, Zhang Y, Matthews H, Montgomery W, Shih H, Jiang J, Jones M, Baras A, Shuldiner A, Gonzaga-Jauregui C, Snapper S, Muise A, Shouval D, Ozen A, Pan K, Wu C, Lenardo M
Cell 2022;185(7):1172-1188.e28
Cell 2022;185(7):1172-1188.e28
ST6GALNAC1 plays important roles in enhancing cancer stem phenotypes of colorectal cancer via the Akt pathway.
Ogawa T, Hirohashi Y, Murai A, Nishidate T, Okita K, Wang L, Ikehara Y, Satoyoshi T, Usui A, Kubo T, Nakastugawa M, Kanaseki T, Tsukahara T, Kutomi G, Furuhata T, Hirata K, Sato N, Mizuguchi T, Takemasa I, Torigoe T
Oncotarget 2017 Dec 22;8(68):112550-112564
Oncotarget 2017 Dec 22;8(68):112550-112564
The androgen receptor controls expression of the cancer-associated sTn antigen and cell adhesion through induction of ST6GalNAc1 in prostate cancer
Munkley J, Oltean S, Vodák D, Wilson B, Livermore K, Zhou Y, Star E, Floros V, Johannessen B, Knight B, McCullagh P, McGrath J, Crundwell M, Skotheim R, Robson C, Leung H, Harries L, Rajan P, Mills I, Elliott D
Oncotarget 2015;6(33):34358-34374
Oncotarget 2015;6(33):34358-34374
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human rectum and skeletal muscle tissues using HPA014975 antibody. Corresponding ST6GALNAC1 RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol