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Learn60227-1-Ig
antibody from Proteintech Group
Targeting: IFT88
D13S1056E, hTg737, MGC26259, Tg737, TTC10
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [12]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 60227-1-Ig - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#60227-1-Ig, RRID:AB_11042449
- Product name
- IFT88 antibody
- Antibody type
- Monoclonal
- Description
- IFT88 antibody (Cat. #60227-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 4A4G5
- Vial size
- 20ul, 150ul
Submitted references Ciliary IFT88 inhibits intervertebral disc degeneration under excessive mechanical stress by regulating endplate cartilage calcification.
Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells.
Synchronized Temporal-spatial Analysis via Microscopy and Phospho-proteomics (STAMP) of Quiescence.
TTBK2 affects sperm quality by regulating the expression of centrosomal proteins and flagellar transporters during spermiogenesis in mice.
Synchronized temporal-spatial analysis via microscopy and phosphoproteomics (STAMP) of quiescence.
Mutant p53 upregulates HDAC6 to resist ER stress and facilitates Ku70 deacetylation, which prevents its degradation and mitigates DNA damage in colon cancer cells.
Primary cilia-mediated regulation of microglial secretion in Alzheimer's disease.
Microtubule Stabilization Enhances the Chondrogenesis of Synovial Mesenchymal Stem Cells.
2-IPMA Ameliorates PM2.5-Induced Inflammation by Promoting Primary Ciliogenesis in RPE Cells.
Crosstalk between the COX2-PGE2-EP4 signaling pathway and primary cilia in osteoblasts after mechanical stimulation.
Ttc39c is upregulated during skeletal muscle atrophy and modulates ERK1/2 MAP kinase and hedgehog signaling.
Chibby functions to preserve normal ciliary morphology through the regulation of intraflagellar transport in airway ciliated cells.
Dong ZR, Wang J, Huang YK, Ding W, He HX, Yuan GC, Gao ZY, Ge YX, Wang WX, Jiang LB, Zhao MD
Journal of advanced research 2026 Mar;81:157-173
Journal of advanced research 2026 Mar;81:157-173
Inhibition of primary ciliogenesis enhances efficacy of EGFR‑TKIs against non‑small cell lung cancer cells.
Jin L, Wei L, Hua J, Zhang R, Chen J, He J, Yang Y
Oncology reports 2026 Feb;55(2)
Oncology reports 2026 Feb;55(2)
Synchronized Temporal-spatial Analysis via Microscopy and Phospho-proteomics (STAMP) of Quiescence.
Azizzanjani MO, Turn RE, Asthana A, Linde-Garelli KY, Xu LA, Labrie LE, Mobedi M, Jackson PK
bioRxiv : the preprint server for biology 2025 Mar 10;
bioRxiv : the preprint server for biology 2025 Mar 10;
TTBK2 affects sperm quality by regulating the expression of centrosomal proteins and flagellar transporters during spermiogenesis in mice.
Chang T, Wu H, Zhang X, Mao F, Bian H, Dai H, Luo H, Hu S, Feng R, Qian Y
Molecular human reproduction 2025 Jul 3;31(3)
Molecular human reproduction 2025 Jul 3;31(3)
Synchronized temporal-spatial analysis via microscopy and phosphoproteomics (STAMP) of quiescence.
Azizzanjani MO, Turn RE, Asthana A, Linde-Garelli KY, Xu LA, Labrie LE, Mobedi M, Jackson PK
Science advances 2025 Apr 25;11(17):eadt9712
Science advances 2025 Apr 25;11(17):eadt9712
Mutant p53 upregulates HDAC6 to resist ER stress and facilitates Ku70 deacetylation, which prevents its degradation and mitigates DNA damage in colon cancer cells.
Benedetti R, Di Crosta M, Gilardini Montani MS, D'Orazi G, Cirone M
Cell death discovery 2025 Apr 10;11(1):162
Cell death discovery 2025 Apr 10;11(1):162
Primary cilia-mediated regulation of microglial secretion in Alzheimer's disease.
Yeo S, Jang J, Jung HJ, Lee H, Choe Y
Frontiers in molecular biosciences 2023;10:1250335
Frontiers in molecular biosciences 2023;10:1250335
Microtubule Stabilization Enhances the Chondrogenesis of Synovial Mesenchymal Stem Cells.
Li J, Sun Z, Lv Z, Jiang H, Liu A, Wang M, Tan G, Guo H, Sun H, Wu R, Xu X, Yan W, Jiang Q, Ikegawa S, Shi D
Frontiers in cell and developmental biology 2021;9:748804
Frontiers in cell and developmental biology 2021;9:748804
2-IPMA Ameliorates PM2.5-Induced Inflammation by Promoting Primary Ciliogenesis in RPE Cells.
Choi JY, Bae JE, Kim JB, Jo DS, Park NY, Kim YH, Lee HJ, Kim SH, Kim SH, Jeon HB, Na HW, Choi H, Ryu HY, Ryoo ZY, Lee HS, Cho DH
Molecules (Basel, Switzerland) 2021 Sep 6;26(17)
Molecules (Basel, Switzerland) 2021 Sep 6;26(17)
Crosstalk between the COX2-PGE2-EP4 signaling pathway and primary cilia in osteoblasts after mechanical stimulation.
Li YH, Zhu D, Yang T, Cheng L, Sun J, Tan L
Journal of cellular physiology 2021 Jun;236(6):4764-4777
Journal of cellular physiology 2021 Jun;236(6):4764-4777
Ttc39c is upregulated during skeletal muscle atrophy and modulates ERK1/2 MAP kinase and hedgehog signaling.
Hayes CS, Labuzan SA, Menke JA, Haddock AN, Waddell DS
Journal of cellular physiology 2019 Dec;234(12):23807-23824
Journal of cellular physiology 2019 Dec;234(12):23807-23824
Chibby functions to preserve normal ciliary morphology through the regulation of intraflagellar transport in airway ciliated cells.
Siller SS, Burke MC, Li FQ, Takemaru K
Cell cycle (Georgetown, Tex.) 2015;14(19):3163-72
Cell cycle (Georgetown, Tex.) 2015;14(19):3163-72
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- human testis tissue were subjected to SDS PAGE followed by western blot with 60227-1-Ig(IFT88 antibody) at dilution of 1:1000
- Sample type
- tissue
Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The IFT88 antibody from Proteintech is a mouse monoclonal antibody to a fusion protein of human IFT88. This antibody recognizes human,mouse, rat antigen. The IFT88 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human kidney using 60227-1-Ig(IFT88 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue
