MAB267

antibody from R&D Systems

Targeting: NTF3 NGF2

ELISA (Recommended by provider)

Blocking/Neutralizing (Recommended by provider)

Antibody Data

Product number

MAB267

Provider

R&D Systems

Product name

Anti-Human NT-3 Monoclonal Antibody (Clone 41512)

Antibody type

Monoclonal

Antigen

S. frugiperda insect ovarian cell line Sf 21-derived recombinant human NT-3, Tyr139-Thr257

Description

Protein A or G purified from ascites

Reactivity

Human

Host

Mouse

Antigen sequence

P20783


Isotype

IgG

Vial size

500 µg

References

Submitted references

AAV1.NT-3 gene therapy for charcot-marie-tooth neuropathy.

Sahenk Z, Galloway G, Clark KR, Malik V, Rodino-Klapac LR, Kaspar BK, Chen L, Braganza C, Montgomery C, Mendell JR
Molecular therapy : the journal of the American Society of Gene Therapy 2014 Mar;22(3):511-521

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Neurotrophin-3 production promotes human neuroblastoma cell survival by inhibiting TrkC-induced apoptosis.

Bouzas-Rodriguez J, Cabrera JR, Delloye-Bourgeois C, Ichim G, Delcros JG, Raquin MA, Rousseau R, Combaret V, Bénard J, Tauszig-Delamasure S, Mehlen P
The Journal of clinical investigation 2010 Mar;120(3):850-8

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Neurotrophins modulate monocyte chemotaxis without affecting macrophage function.

Samah B, Porcheray F, Gras G
Clinical and experimental immunology 2008 Mar;151(3):476-86

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The neurotrophins nerve growth factor, brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4 are survival and activation factors for eosinophils in patients with allergic bronchial asthma.

Nassenstein C, Braun A, Erpenbeck VJ, Lommatzsch M, Schmidt S, Krug N, Luttmann W, Renz H, Virchow JC Jr
The Journal of experimental medicine 2003 Aug 4;198(3):455-67