Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 55245-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#55245-1-AP, RRID:AB_10951108
- Product name
- HCN2 antibody
- Antibody type
- Polyclonal
- Description
- HCN2 antibody (Cat. #55245-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references HCN-Channel-Dependent Hyperexcitability of the Layer V Pyramidal Neurons in IL-mPFC Contributes to Fentanyl-Induced Hyperalgesia in Male Rats.
Thalamocortical Circuit Controls Neuropathic Pain via Up-regulation of HCN2 in the Ventral Posterolateral Thalamus.
Optogenetic Activation of Striatopallidal Neurons Reveals Altered HCN Gating in DYT1 Dystonia.
HCN2 contributes to oxaliplatin-induced neuropathic pain by inducing spinal long-term potentiation via activation of NMDA receptor-mediated CaMKII signaling.
HCN2 contributes to oxaliplatin-induced neuropathic pain through activation of the CaMKII/CREB cascade in spinal neurons.
Effect of mHCN2 gene modification on chronotropic relevant receptors in BMSCs co-cultured with atrial myocytes.
Non-CpG methylation by DNMT3B facilitates REST binding and gene silencing in developing mouse hearts.
Wang X, Gan S, Zhang Z, Zhu P, Li CH, Luo F
Molecular neurobiology 2023 May;60(5):2553-2571
Molecular neurobiology 2023 May;60(5):2553-2571
Thalamocortical Circuit Controls Neuropathic Pain via Up-regulation of HCN2 in the Ventral Posterolateral Thalamus.
Yan Y, Zhu M, Cao X, Xu G, Shen W, Li F, Zhang J, Luo L, Zhang X, Zhang D, Liu T
Neuroscience bulletin 2023 May;39(5):774-792
Neuroscience bulletin 2023 May;39(5):774-792
Optogenetic Activation of Striatopallidal Neurons Reveals Altered HCN Gating in DYT1 Dystonia.
Sciamanna G, Ponterio G, Vanni V, Laricchiuta D, Martella G, Bonsi P, Meringolo M, Tassone A, Mercuri NB, Pisani A
Cell reports 2020 May 19;31(7):107644
Cell reports 2020 May 19;31(7):107644
HCN2 contributes to oxaliplatin-induced neuropathic pain by inducing spinal long-term potentiation via activation of NMDA receptor-mediated CaMKII signaling.
Liu X, Ji Q, Liu F, Jin L, Tan Y, Zhang L, Tang J
Brain research bulletin 2020 Jun;159:61-66
Brain research bulletin 2020 Jun;159:61-66
HCN2 contributes to oxaliplatin-induced neuropathic pain through activation of the CaMKII/CREB cascade in spinal neurons.
Liu X, Zhang L, Jin L, Tan Y, Li W, Tang J
Molecular pain 2018 Jan-Dec;14:1744806918778490
Molecular pain 2018 Jan-Dec;14:1744806918778490
Effect of mHCN2 gene modification on chronotropic relevant receptors in BMSCs co-cultured with atrial myocytes.
Ding C, Yang C, Cao Q, Zhu X, Zhang J, Zhang W, Wang Y, Li L
Experimental and therapeutic medicine 2017 Sep;14(3):2108-2116
Experimental and therapeutic medicine 2017 Sep;14(3):2108-2116
Non-CpG methylation by DNMT3B facilitates REST binding and gene silencing in developing mouse hearts.
Zhang D, Wu B, Wang P, Wang Y, Lu P, Nechiporuk T, Floss T, Greally JM, Zheng D, Zhou B
Nucleic acids research 2017 Apr 7;45(6):3102-3115
Nucleic acids research 2017 Apr 7;45(6):3102-3115
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- mouse brain tissue were subjected to SDS PAGE followed by western blot with 55245-1-AP(HCN2 antibody) at dilution of 1:800
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human heart using 55245-1-AP(HCN2 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The HCN2 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human HCN2. This antibody recognizes human, mouse, rat antigen. The HCN2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
