66647-1-Ig

antibody from Proteintech Group

Targeting: RNF126 FLJ20552

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Antibody Data

Product number

66647-1-Ig

Provider

Proteintech Group

Product name

RNF126 antibody

Antibody type

Monoclonal

Description

KD/KO validated RNF126 antibody (Cat. #66647-1-Ig) is a mouse monoclonal antibody that shows reactivity with Human, mouse, rat and has been validated for the following applications: WB,ELISA.

Reactivity

Human, Mouse, Rat

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

1E1B10

Vial size

20ul, 150ul

References

Submitted references

Poly(ADP-ribose) glycohydrolase enforces p21 degradation via dePARylation to promote gastric cancer progression.

Hu Y, Bao Q, Huang Y, Wang Y, Zhao X, Nan J, Meng Y, Deng M, Li Y, Zhuang Z, He H, Zu D, Zhong Y, Zhang C, Wang B, Li R, He Y, Wang Q, Liu M, Tainer JA, Shi Y, Cheng X, Jing J, Ye Z
The Journal of clinical investigation 2026 Mar 2;136(5)

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Dipyridamole Acts as Clinical Ferroptosis Inhibitor to Prevent from Tissue Injury.

Zhuang X, Shi S, Liu S, Jiao Y, Huang B, Yang Y, Yang L, Yang X, Wang H, Liang C, Song D, Yu H, Zou D, Sun Q, Yang S, Yin C, Li J, Liu Y, Min J, Wang F, Nian Y, Du L, Chu B
Advanced science (Weinheim, Baden-Wurttemberg, Germany) 2025 Jun;12(23):e2500566

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Discovery of the first examples of right open reading frame kinase 2 (RIOK2) molecular glue degraders.

Ma H, Liu C, Li Z, Yu Q, Xiong H, Huang C, Tan L, Zhan M, Zhang Z, Cai Q
European journal of medicinal chemistry 2025 Feb 5;283:117166

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RNF126 suppresses amino acid-mediated mTORC1 signaling pathway by ubiquitinating ILF3 in HEK293T cells.

Hu B, Shang MD, Wang X, Zhang XG, Dong MH, Cao Q, Wei XD, Han YC, Li F, Yang ZL, Liu LY, Wang JQ
Cellular signalling 2025 Dec;136:112110

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Ring-Finger Protein 126 (RNF126) Promotes Anoikis Resistance and Peritoneal Colonization in Ovarian Cancer.

Vu AD, Mori S, Akamatsu K, Nakayama J, Sakamoto T
International journal of molecular sciences 2025 Dec 18;26(24)

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ZNF263 cooperates with ZNF31 to promote the drug resistance and EMT of pancreatic cancer through transactivating RNF126.

Zhang J, Chen C, Geng Q, Li H, Wu M, Chan B, Wang S, Sheng W
Journal of cellular physiology 2024 Jun;239(6):e31259

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DCAF16-Based Covalent Handle for the Rational Design of Monovalent Degraders.

Lim M, Cong TD, Orr LM, Toriki ES, Kile AC, Papatzimas JW, Lee E, Lin Y, Nomura DK
ACS central science 2024 Jul 24;10(7):1318-1331

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Bortezomib inhibits ZIKV/DENV by interfering with viral polyprotein cleavage via the ERAD pathway.

Ci Y, Yao B, Yue K, Yang Y, Xu C, Li DF, Qin CF, Shi L
Cell chemical biology 2023 May 18;30(5):527-539.e5

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ARIH2 regulates the proliferation, DNA damage and chemosensitivity of gastric cancer cells by reducing the stability of p21 via ubiquitination.

Geng S, Peng W, Wang X, Hu X, Liang H, Hou J, Wang F, Zhao G, Lü M, Cui H
Cell death & disease 2022 Jun 22;13(6):564

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Retinitis pigmentosa 2 pathogenic mutants degrade through BAG6/HUWE1 complex.

Zhang J, Gao H, Jiang N, Jing M, Sun Z, Du C, Zhang J, Wang M, Li J, Gao F, Hu Y, Mu H, Cui X
Experimental eye research 2022 Jul;220:109110

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RNF126-Mediated Reubiquitination Is Required for Proteasomal Degradation of p97-Extracted Membrane Proteins.

Hu X, Wang L, Wang Y, Ji J, Li J, Wang Z, Li C, Zhang Y, Zhang ZR
Molecular cell 2020 Jul 16;79(2):320-331.e9