BS7837

antibody from Bioworld Technology, Inc
Targeting: PVR CD155, HVED, Necl-5, NECL5, PVS, Tage4
Provider product page for BS7837
Western blot
Immunohistochemistry

Antibody data

Product number
BS7837 - Provider product page
Provider
Bioworld Technology, Inc
Product name
PVR polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human PVR.
Description
CD155, a member of the immunoglobulin superfamily, acts as the human receptor for poliovirus (PV). All three serotypes of PV- PV1, 2, and 3- exhibit similar binding to CD155 in both its glycosylated and fully deglycosylated forms, indicating they utilize a common mechanism for cell entry. Additionally, CD155 undergoes cell-matrix contacts by binding to the matrix protein vitronectin. Along with the receptor form, three soluble isoforms, Ï« ÉÇ, and ÎÛ, also exist in human serum and cerebrospinal fluid, and CD155 mRNAs are highly expressed in liver tissue. The presence of soluble CD155 reduces polivirus entry mediated by the membrane-bound receptor, implying an important role for these soluble forms in cellular function.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
PVR protein structure - BS7837 shown in red.