17-1550-41

antibody from Invitrogen Antibodies
Targeting: PVR CD155, HVED, Necl-5, NECL5, PVS, Tage4
Provider product page for 17-1550-41

Antibody data

Product number
17-1550-41 - Provider product page
Provider
Invitrogen Antibodies
Product name
Anti-CD155 Monoclonal Antibody (2H7CD155), APC, eBioscience™
Antibody type
Monoclonal
Antigen
Other
Description
Description: The monoclonal antibody 2H7CD155 recognizes CD155 also known as the poliovirus receptor. The CD155 protein is a member of the Ig superfamily in which 4 isoforms exist; only the alpha and delta forms are expressed on the membrane of monocytes, prostate cancer cells, as well as neurectodermal and monocytic tumor cells lines. In addition, CD155 is found during mid-gastrulation during embryonic development. CD155 is thought to play a role in adhesion by interaction with the ECM component vitronectin as well as a role in NK killing of tumor cells. CD226 and CD96 are ligands for CD155. Blocking of CD155 is under therapeutic investigation for prevention of variants of poliovirus. Applications Reported: This 2H7CD155 antibody has been reported for use in flow cytometric analysis. Applications Tested: This 2H7CD155 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells or the human tumor cell line U937. This may be used at 5 µL (0.25 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Excitation: 633-647 nm; Emission: 660 nm; Laser: Red Laser
Reactivity
Human
Host
Mouse
Isotype
IgG
Antibody clone number
2H7CD155
Vial size
25 Tests
Concentration
5 µL/Test
Storage
4° C, store in dark, DO NOT FREEZE!
PVR protein structure - 17-1550-41 shown in red.