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Learn17-1550-42
antibody from Invitrogen Antibodies
Targeting: PVR
CD155, HVED, Necl-5, NECL5, PVS, Tage4
Flow cytometryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Flow cytometry [1]
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- Product number
- 17-1550-42 - Provider product page
- Provider
- Invitrogen Antibodies
- Product name
- CD155 Monoclonal Antibody (2H7CD155), APC, eBioscience™
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- Description: The monoclonal antibody 2H7CD155 recognizes CD155 also known as the poliovirus receptor. The CD155 protein is a member of the Ig superfamily in which 4 isoforms exist; only the alpha and delta forms are expressed on the membrane of monocytes, prostate cancer cells, as well as neurectodermal and monocytic tumor cells lines. In addition, CD155 is found during mid-gastrulation during embryonic development. CD155 is thought to play a role in adhesion by interaction with the ECM component vitronectin as well as a role in NK killing of tumor cells. CD226 and CD96 are ligands for CD155. Blocking of CD155 is under therapeutic investigation for prevention of variants of poliovirus.
- Antibody clone number
- 2H7CD155
- Concentration
- 5 µL/Test
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Supportive validation
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- Invitrogen Antibodies (provider)
- Main image
- Experimental details
- U937 cells were stained with Mouse IgG1 kappa Isotype Control, APC (Product # 17-4714-82) (blue histogram) or CD155 Monoclonal Antibody, APC (purple histogram). Total viable cells were used for analysis.
