BS6508

antibody from Bioworld Technology, Inc
Targeting: NAT1 AAC1
Provider product page for BS6508
Western blot
Immunohistochemistry

Antibody data

Product number
BS6508 - Provider product page
Provider
Bioworld Technology, Inc
Product name
NAT1 polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human NAT1.
Description
Arylamine N-acetyltransferases (NAT-1 and NAT-2) catalyze N- or O-acetylation of heterocyclic and arylamine substrates in the detoxification of a wide array of drugs. Certain alleles causing high N-acetyltransferase activity have been associated with colon and urinary bladder cancers, as NATs also bioactivate several known carcinogens. Both NAT-1 and NAT-2 are cytoplasmic proteins and play an active role in the detoxification of many arylamine and hydrazine drugs. N-acetylation polymorphism is determined by the level of NAT activity in liver tissues, and has been linked to the action and toxicity of drugs that contain amines. Human NAT-1 is the functional homolog of rodent NAT-2, while human NAT-2 is the functional homolog of rodent NAT-1.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
NAT1 protein structure - BS6508 shown in red.