HPA012569

antibody from Atlas Antibodies

Targeting: CDHR2 FLJ20124, FLJ20383, PC-LKC, PCDH24, PCLKC

Immunohistochemistry (Data presented on provider website)

Antibody Data

Product number

HPA012569

Provider

Atlas Antibodies

Proper citation

Atlas Antibodies Cat#HPA012569, RRID:AB_1845298

Product name

Anti-CDHR2

Antibody type

Polyclonal

Description

Polyclonal Antibody against Human CDHR2, Gene description: cadherin-related family member 2, Alternative Gene Names: FLJ20124, FLJ20383, PC-LKC, PCDH24, PCLKC, Validated applications: IHC, Uniprot ID: Q9BYE9, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

100 µl

Concentration

0.1 mg/ml

Storage

Store at +4°C for short term storage. Long time storage is recommended at -20°C.

Handling

The antibody solution should be gently mixed before use.

References

Submitted references

Defects in microvillus crosslinking sensitize to colitis and inflammatory bowel disease

Mödl B, Awad M, Zwolanek D, Scharf I, Schwertner K, Milovanovic D, Moser D, Schmidt K, Pjevac P, Hausmann B, Krauß D, Mohr T, Svinka J, Kenner L, Casanova E, Timelthaler G, Sibilia M, Krieger S, Eferl R
EMBO reports 2023;24(10)

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A heterologous in-cell assay for investigating intermicrovillar adhesion complex interactions reveals a novel protrusion length-matching mechanism

Weck M, Crawley S, Tyska M
Journal of Biological Chemistry 2020;295(48):16191-16206

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A cryptic sequence targets the adhesion complex scaffold ANKS4B to apical microvilli to promote enterocyte brush border assembly

Graves M, Matoo S, Choi M, Storad Z, El Sheikh Idris R, Pickles B, Acharya P, Shinder P, Arvay T, Crawley S
Journal of Biological Chemistry 2020;295(36):12588-12604

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The small EF-hand protein CALML4 functions as a critical myosin light chain within the intermicrovillar adhesion complex

Choi M, Graves M, Matoo S, Storad Z, El Sheikh Idris R, Weck M, Smith Z, Tyska M, Crawley S
Journal of Biological Chemistry 2020;295(28):9281-9296

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Brush border protocadherin CDHR2 promotes the elongation and maximized packing of microvilli in vivo

Pinette J, Mao S, Millis B, Krystofiak E, Faust J, Tyska M, Nusrat A
Molecular Biology of the Cell 2019;30(1):108-118

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Structure of Myo7b/USH1C complex suggests a general PDZ domain binding mode by MyTH4-FERM myosins

Li J, He Y, Weck M, Lu Q, Tyska M, Zhang M
Proceedings of the National Academy of Sciences 2017;114(19)

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ANKS4B Is Essential for Intermicrovillar Adhesion Complex Formation

Crawley S, Weck M, Grega-Larson N, Shifrin D, Tyska M
Developmental Cell 2016;36(2):190-200

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Proteomic analysis of the enterocyte brush border

McConnell R, Benesh A, Mao S, Tabb D, Tyska M
American Journal of Physiology-Gastrointestinal and Liver Physiology 2011;300(5):G914-G926