Tissue expression
Cell line expression
Protein structure
PSMD13
Proteasome 26S subunit, non-ATPase 13p40.5, Rpn9
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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Proteintech Group | 15261-1-AP | 4 references | Polyclonal |
WB
EL
ICC
IP
IHC
|
|
Invitrogen Antibodies | 15261-1-AP | Polyclonal |
WB
ICC
IP
IHC
OA
|
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antibodies-online | ABIN2035270 | Polyclonal |
WB
EL
IHC
FC |
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Aviva Systems Biology | OAAB01691 | Polyclonal |
WB
EL
IHC
FC |
||
Abgent | AP2915b | Polyclonal |
WB
IHC
FC
|
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