Antibody data
- Antibody Data
- Antigen structure
- References [5]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
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Validation data
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- Product number
- 15459-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#15459-1-AP, RRID:AB_10859096
- Product name
- TNIP2 antibody
- Antibody type
- Polyclonal
- Description
- TNIP2 antibody (Cat. #15459-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references TNFAIP3 interacting protein 2 relieves lipopolysaccharide (LPS)-induced inflammatory injury in endometritis by inhibiting NF-kappaB activation.
Protective effect of TNIP2 on the inflammatory response of microglia after spinal cord injury in rats.
TNIP2 inhibits amyloidogenesis by regulating the 3'UTR of BACE1: An in vitro study.
Foot-and-Mouth Disease Virus Structural Protein VP1 Destroys the Stability of TPL2 Trimer by Degradation TPL2 to Evade Host Antiviral Immunity.
The kinase TPL2 activates ERK and p38 signaling to promote neutrophilic inflammation.
Qian X, Wang Y, Li X, Li Y, Li L
Immunity, inflammation and disease 2023 Oct;11(10):e970
Immunity, inflammation and disease 2023 Oct;11(10):e970
Protective effect of TNIP2 on the inflammatory response of microglia after spinal cord injury in rats.
Fu J, Wu C, Xu G, Zhang J, Chen J, Chen C, Hong H, Xue P, Jiang J, Huang J, Ji C, Cui Z
Neuropeptides 2023 Oct;101:102351
Neuropeptides 2023 Oct;101:102351
TNIP2 inhibits amyloidogenesis by regulating the 3'UTR of BACE1: An in vitro study.
Chen L, Wang L, Zhou GF, Liu Y, Chen X, Xie XY, Wen QX, Li CL, Yang J, Chen GJ
Neuroscience letters 2023 Jun 21;808:137265
Neuroscience letters 2023 Jun 21;808:137265
Foot-and-Mouth Disease Virus Structural Protein VP1 Destroys the Stability of TPL2 Trimer by Degradation TPL2 to Evade Host Antiviral Immunity.
Zhang K, Yan M, Hao J, Shen C, Zhu Z, Zhang D, Hou J, Xu G, Li D, Zheng H, Liu X
Journal of virology 2021 Apr 1;95(7)
Journal of virology 2021 Apr 1;95(7)
The kinase TPL2 activates ERK and p38 signaling to promote neutrophilic inflammation.
Senger K, Pham VC, Varfolomeev E, Hackney JA, Corzo CA, Collier J, Lau VWC, Huang Z, Hamidzhadeh K, Caplazi P, Peng I, Setiadi AF, Francis R, Paler-Martinez A, Kwon YC, Ramirez-Carrozzi V, Sun Y, Grigg PW, Roose-Girma M, Jeet S, Barck KH, Pham A, Ota N, Ha C, Stinson J, Guillory J, Tam L, Modrusan Z, Emson C, McKenzie BS, Townsend MJ, Carano RAD, Warming S, Vucic D, DeVoss J, Lee WP, Lill JR, Zarrin AA
Science signaling 2017 Apr 18;10(475)
Science signaling 2017 Apr 18;10(475)
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HepG2 cells were subjected to SDS PAGE followed by western blot with 15459-1-AP(TNIP2 antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using TNIP2 antibody 15459-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 15459-1-AP(TNIP2 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human liver using 15459-1-AP(TNIP2 antibody) at dilution of 1:100 (under 40x lens)
- Sample type
- tissue