Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [2]
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Validation data
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- Product number
- NB110-87320 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB110-87320, RRID:AB_1199458
- Product name
- Rabbit Polyclonal VPS34 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Concentration
- 0.2 mg/ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Rab11 activity and PtdIns(3)P turnover removes recycling cargo from endosomes.
Activation of RARα induces autophagy in SKBR3 breast cancer cells and depletion of key autophagy genes enhances ATRA toxicity.
Saxifragifolin D induces the interplay between apoptosis and autophagy in breast cancer cells through ROS-dependent endoplasmic reticulum stress.
PML-RARα enhances constitutive autophagic activity through inhibiting the Akt/mTOR pathway.
Campa CC, Margaria JP, Derle A, Del Giudice M, De Santis MC, Gozzelino L, Copperi F, Bosia C, Hirsch E
Nature chemical biology 2018 Aug;14(8):801-810
Nature chemical biology 2018 Aug;14(8):801-810
Activation of RARα induces autophagy in SKBR3 breast cancer cells and depletion of key autophagy genes enhances ATRA toxicity.
Brigger D, Schläfli AM, Garattini E, Tschan MP
Cell death & disease 2015 Aug 27;6:e1861
Cell death & disease 2015 Aug 27;6:e1861
Saxifragifolin D induces the interplay between apoptosis and autophagy in breast cancer cells through ROS-dependent endoplasmic reticulum stress.
Shi JM, Bai LL, Zhang DM, Yiu A, Yin ZQ, Han WL, Liu JS, Li Y, Fu DY, Ye WC
Biochemical pharmacology 2013 Apr 1;85(7):913-26
Biochemical pharmacology 2013 Apr 1;85(7):913-26
PML-RARα enhances constitutive autophagic activity through inhibiting the Akt/mTOR pathway.
Huang Y, Hou JK, Chen TT, Zhao XY, Yan ZW, Zhang J, Yang J, Kogan SC, Chen GQ
Autophagy 2011 Oct;7(10):1132-44
Autophagy 2011 Oct;7(10):1132-44
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Simple Western: VPS34 Antibody [NB110-87320] - Simple Western lane view shows a specific band for VPS34 in 0.5 mg/ml of HepG2 lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation system.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: VPS34 Antibody [NB110-87320] - HepG2 whole cell lysates.