Explore
Validate
Learn
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [7]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [1]
- Flow cytometry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 11529-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#11529-1-AP, RRID:AB_2059358
- Product name
- ASCC2 antibody
- Antibody type
- Polyclonal
- Description
- ASCC2 antibody (Cat. #11529-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Histone modification-regulated LncRNA DLEU1 interacts with ASCC2/ALKBH3 complex to drive DNA repair, antioxidant homeostasis and glucose metabolism in gastric cancer.
Disruption of axonal transport in Parkinson's disease: the role of pathological α-Syn and AMPK/p38 MAPK signaling.
The Ski2 helicase ASCC3 unwinds DNA upon fork stalling to control replication stress responses.
Pan-cancer analysis reveals ASCC family promotes the cancer progression of lung adenocarcinoma.
Du Huo Ji Sheng Tang inhibits Notch1 signaling and subsequent NLRP3 activation to alleviate cartilage degradation in KOA mice.
Extended DNA threading through a dual-engine motor module of the activating signal co-integrator 1 complex.
The interaction of DNA repair factors ASCC2 and ASCC3 is affected by somatic cancer mutations.
Zhang X, Wang X, Wang Q, Wang X, Sun H, Liu Y, Tan C, Ni S, Weng W, Zhang M, Wang L, Huang D, Chen J, Wang X, Gan L, Abudurexiti M, Wang W, Chang J, Sheng W, Xu M
Biomarker research 2026 Jan 2;14(1):1
Biomarker research 2026 Jan 2;14(1):1
Disruption of axonal transport in Parkinson's disease: the role of pathological α-Syn and AMPK/p38 MAPK signaling.
Yang X, Ma Z, Lian P, Wu Y, Liu K, Zhang Z, Tang Z, Xu Y, Cao X
NPJ Parkinson's disease 2025 May 6;11(1):114
NPJ Parkinson's disease 2025 May 6;11(1):114
The Ski2 helicase ASCC3 unwinds DNA upon fork stalling to control replication stress responses.
Cui S, Batenburg NL, Coulombe Y, Arumugam A, Walker JR, Sheida SV, Bielinsky AK, Wahl MC, Masson JY, Zhu XD
bioRxiv : the preprint server for biology 2025 Jul 26;
bioRxiv : the preprint server for biology 2025 Jul 26;
Pan-cancer analysis reveals ASCC family promotes the cancer progression of lung adenocarcinoma.
Pan Y, Tan J, Wu C, Liu C, Chen Z, Zhu Y, Luo F, Liu Q
Scientific reports 2025 Jul 2;15(1):22799
Scientific reports 2025 Jul 2;15(1):22799
Du Huo Ji Sheng Tang inhibits Notch1 signaling and subsequent NLRP3 activation to alleviate cartilage degradation in KOA mice.
Chen WJ, Zhuang Y, Peng W, Cui W, Zhang SJ, Wang JW
Chinese medicine 2023 Jun 29;18(1):80
Chinese medicine 2023 Jun 29;18(1):80
Extended DNA threading through a dual-engine motor module of the activating signal co-integrator 1 complex.
Jia J, Hilal T, Bohnsack KE, Chernev A, Tsao N, Bethmann J, Arumugam A, Parmely L, Holton N, Loll B, Mosammaparast N, Bohnsack MT, Urlaub H, Wahl MC
Nature communications 2023 Apr 5;14(1):1886
Nature communications 2023 Apr 5;14(1):1886
The interaction of DNA repair factors ASCC2 and ASCC3 is affected by somatic cancer mutations.
Jia J, Absmeier E, Holton N, Pietrzyk-Brzezinska AJ, Hackert P, Bohnsack KE, Bohnsack MT, Wahl MC
Nature communications 2020 Nov 2;11(1):5535
Nature communications 2020 Nov 2;11(1):5535
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HeLa cells were subjected to SDS PAGE followed by western blot with 11529-1-AP( ASCC2 Antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunofluorescent analysis of HepG2 cells, using ASCC2 antibody 11529-1-AP at 1:25 dilution and Rhodamine-labeled goat anti-rabbit IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human colon cancer using 11529-1-AP(ASCC2 antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The ASCC2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human ASCC2. This antibody recognizes human,mouse,rat antigen. The ASCC2 antibody has been validated for the following applications: ELISA, IHC, IF, WB, FC analysis.
