Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 16841-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#16841-1-AP, RRID:AB_2185750
- Product name
- SETBP1 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SETBP1 antibody (Cat. #16841-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Myb expression is critical for myeloid leukemia development induced by Setbp1 activation.
Somatic SETBP1 mutations in myeloid malignancies.
Setbp1 promotes the self-renewal of murine myeloid progenitors via activation of Hoxa9 and Hoxa10.
Nguyen N, Vishwakarma BA, Oakley K, Han Y, Przychodzen B, Maciejewski JP, Du Y
Oncotarget 2016 Dec 27;7(52):86300-86312
Oncotarget 2016 Dec 27;7(52):86300-86312
Somatic SETBP1 mutations in myeloid malignancies.
Makishima H, Yoshida K, Nguyen N, Przychodzen B, Sanada M, Okuno Y, Ng KP, Gudmundsson KO, Vishwakarma BA, Jerez A, Gomez-Segui I, Takahashi M, Shiraishi Y, Nagata Y, Guinta K, Mori H, Sekeres MA, Chiba K, Tanaka H, Muramatsu H, Sakaguchi H, Paquette RL, McDevitt MA, Kojima S, Saunthararajah Y, Miyano S, Shih LY, Du Y, Ogawa S, Maciejewski JP
Nature genetics 2013 Aug;45(8):942-6
Nature genetics 2013 Aug;45(8):942-6
Setbp1 promotes the self-renewal of murine myeloid progenitors via activation of Hoxa9 and Hoxa10.
Oakley K, Han Y, Vishwakarma BA, Chu S, Bhatia R, Gudmundsson KO, Keller J, Chen X, Vasko V, Jenkins NA, Copeland NG, Du Y
Blood 2012 Jun 21;119(25):6099-108
Blood 2012 Jun 21;119(25):6099-108
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The SETBP1 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human SETBP1. This antibody recognizes human,mouse,rat antigen. The SETBP1 antibody has been validated for the following applications: ELISA, WB analysis.