DCABH-2915

antibody from Creative Diagnostics

Targeting: MCAM CD146, HEMCAM, MelCAM, METCAM, MUC18

Western blot (Recommended by provider)

Antibody Data

Product number

DCABH-2915

Provider

Creative Diagnostics

Proper citation

Creative Diagnostics Cat#DCABH-2915, RRID:AB_2476793

Product name

Rabbit Anti-Human CD146 monoclonal antibody, clone 3I28M25

Antibody type

Monoclonal

Description

MUC18, also known as CD146 is an integral membrane glycoprotein belonging to the immunoglobulin superfamily. The protein is expressed at cell-cell junctions in all endothelial cells, and has also been observed in other normal and malignant cell types. In addition to its recognized role as a calcium-independent cell adhesion molecule, MUC18 may also act as a signal transduction molecule in the recruitment of Fyn kinase, and in the subsequent tyrosine-phosphorylation of intracellular proteins involved in actin cytoskeleton assembly.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

3I28M25

Concentration

0.5 mg/ml

Storage

Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C