Antibody data
- Antibody Data
- Antigen structure
- References [0]
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- Validations
- Immunohistochemistry [3]
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- Product number
- NBP2-48166 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal MCAM/CD146 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified. The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 7 ml
- Storage
- Store at 4C.
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: MCAM/CD146 Antibody (MCAM/1101) - IHC-Prediluted [NBP2-48166] - Human Melanoma stained with MCAM Monoclonal Antibody (MCAM/1101)
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: MCAM/CD146 Antibody (MCAM/1101) - IHC-Prediluted [NBP2-48166] - Human Melanoma stained with MCAM Monoclonal Antibody (MCAM/1101)
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: MCAM/CD146 Antibody (MCAM/1101) - IHC-Prediluted [NBP2-48166] - Human Tonsil stained with MCAM Monoclonal Antibody (MCAM/1101)