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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Immunohistochemistry [5]
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- Product number
- NBP2-48207 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Mouse Monoclonal MCAM/CD146 Antibody
- Antibody type
- Monoclonal
- Description
- Protein A or G purified. The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.
- Reactivity
- Human
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 7 ml
- Storage
- Store at 4C.
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: MCAM/CD146 Antibody (MUC18/1130) - IHC-Prediluted [NBP2-48207] - Formalin-fixed, paraffin-embedded human Melanoma stained with MUC18 Mouse Monoclonal Antibody (MUC18/1130).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: MCAM/CD146 Antibody (MUC18/1130) - IHC-Prediluted [NBP2-48207] - Formalin-fixed, paraffin-embedded human Melanoma stained with MUC18 Mouse Monoclonal Antibody (MUC18/1130).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: MCAM/CD146 Antibody (MUC18/1130) - IHC-Prediluted [NBP2-48207] - Formalin-fixed, paraffin-embedded human Tonsil stained with MUC18 Mouse Monoclonal Antibody (MUC18/1130).
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: MCAM/CD146 Antibody (MUC18/1130) - IHC-Prediluted [NBP2-48207] - CD146 was stained in both human brain and pancreatic tissues. CD146 expression was high in pancreatic tissue, yet low in brain tissue as shown by the brown coloration. Image from a verified customer review.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: MCAM/CD146 Antibody (MUC18/1130) - IHC-Prediluted [NBP2-48207] - CD146 Staining of Normal Human Tissues. Image from a verified customer review.
