FNab01429

antibody from FineTest Biotech

Targeting: MCAM CD146, HEMCAM, MelCAM, METCAM, MUC18

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ELISA

Immunohistochemistry

Flow cytometry

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Validation data

Product number: FNab01429 - Provider product page
Provider: FineTest Biotech
Product name: CD146/MCAM antibody
Antibody type: Monoclonal
Antigen: Recombinant protein fragment
Description: CD146, also known as melanoma cell adhesion molecule(MCAM) or MUC18, originally identified as a biomarker of melanoma progression, is a transmembrane glycoprotein belonging to the immunoglobulin(Ig) superfamily(PMID: 8378324). Structurally, it consists of five Ig domains, a transmembrane domain, and a cytoplasmic region. In normal adult tissue, CD146 is primarily expressed by vascular endothelium and smooth muscle. CD146 is a key cell adhesion protein in vascular endothelial cell activity and angiogenesis, and has been used as marker of circulating endothelium cells(CECs)(PMID: 19356677).
Reactivity: Human
Host: Mouse
Conjugate: Unconjugated
Antigen sequence: melanoma cell adhesion molecule
Epitope: IgG1
Isotype: IgG
Antibody clone number: 0
Vial size: 100¦Ìg
Concentration: Protein A+G purification
Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)
Handling: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20¡æ for 12 months(Avoid repeated freeze / thaw cycles.)

MCAM protein structure - FNab01429 shown in red.