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ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Immunohistochemistry [1]
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- Product number
- HPA008848 - Provider product page
- Provider
- Atlas Antibodies
- Proper citation
- Atlas Antibodies Cat#HPA008848, RRID:AB_1078445
- Product name
- Anti-MCAM
- Antibody type
- Polyclonal
- Description
- Polyclonal Antibody against Human MCAM, Gene description: melanoma cell adhesion molecule, Alternative Gene Names: CD146, MUC18, Validated applications: IHC, WB, Uniprot ID: P43121, Storage: Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µl
- Concentration
- 0.3 mg/ml
- Storage
- Store at +4°C for short term storage. Long time storage is recommended at -20°C.
- Handling
- The antibody solution should be gently mixed before use.
Submitted references Development of 42 marker panel for in-depth study of cancer associated fibroblast niches in breast cancer using imaging mass cytometry.
Single-cell analysis reveals prognostic fibroblast subpopulations linked to molecular and immunological subtypes of lung cancer
Fibroblast activation and inflammation in frozen shoulder
MCAM and LAMA4 Are Highly Enriched in Tumor Blood Vessels of Renal Cell Carcinoma and Predict Patient Outcome.
Glutamate dependent NMDA receptor 2D is a novel angiogenic tumour endothelial marker in colorectal cancer.
Røgenes H, Finne K, Winge I, Akslen LA, Östman A, Milosevic V
Frontiers in immunology 2024;15:1325191
Frontiers in immunology 2024;15:1325191
Single-cell analysis reveals prognostic fibroblast subpopulations linked to molecular and immunological subtypes of lung cancer
Hanley C, Waise S, Ellis M, Lopez M, Pun W, Taylor J, Parker R, Kimbley L, Chee S, Shaw E, West J, Alzetani A, Woo E, Ottensmeier C, Rose-Zerilli M, Thomas G
Nature Communications 2023;14(1)
Nature Communications 2023;14(1)
Fibroblast activation and inflammation in frozen shoulder
Mohamadi A, Akbar M, McLean M, Garcia-Melchor E, Crowe L, McMillan P, Fazzi U, Martin D, Arthur A, Reilly J, McInnes I, Millar N
PLOS ONE 2019;14(4):e0215301
PLOS ONE 2019;14(4):e0215301
MCAM and LAMA4 Are Highly Enriched in Tumor Blood Vessels of Renal Cell Carcinoma and Predict Patient Outcome.
Wragg JW, Finnity JP, Anderson JA, Ferguson HJ, Porfiri E, Bhatt RI, Murray PG, Heath VL, Bicknell R
Cancer research 2016 Apr 15;76(8):2314-26
Cancer research 2016 Apr 15;76(8):2314-26
Glutamate dependent NMDA receptor 2D is a novel angiogenic tumour endothelial marker in colorectal cancer.
Ferguson HJ, Wragg JW, Ward S, Heath VL, Ismail T, Bicknell R
Oncotarget 2016 Apr 12;7(15):20440-54
Oncotarget 2016 Apr 12;7(15):20440-54
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Supportive validation
- Submitted by
- Atlas Antibodies (provider)
- Enhanced method
- Orthogonal validation
- Main image
- Experimental details
- Immunohistochemistry analysis in human placenta and liver tissues using HPA008848 antibody. Corresponding MCAM RNA-seq data are presented for the same tissues.
- Sample type
- Human
- Protocol
- Protocol
