66037-1-Ig
antibody from Proteintech Group
Targeting: ATP5F1A
ATP5A, ATP5A1, ATP5AL2, ATPM, hATP1, OMR, ORM
Antibody data
- Antibody Data
- Antigen structure
- References [47]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
- Immunohistochemistry [2]
Submit
Validation data
Reference
Comment
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- Product number
- 66037-1-Ig - Provider product page

- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#66037-1-Ig, RRID:AB_11044196
- Product name
- ATP5A1 antibody
- Antibody type
- Monoclonal
- Description
- ATP5A1 antibody (Cat. #66037-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, mouse, rat, monkey and has been validated for the following applications: FC, IF, IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Simian
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Antibody clone number
- 1B10H3
- Vial size
- 20ul, 150ul
Submitted references Shenkangling alleviates renal fibrosis induced by renal ischemia-reperfusion injury by mitigating mitochondrial damage through modulation of the STING signaling pathway.
UFMylation of Pyruvate Dehydrogenase Regulates Mitochondrial Metabolism.
Txnrd2 loss in skeletal muscle causes muscle atrophy and drives leanness and obesity resistance.
UQCRC1 deficiency impairs mitophagy via PINK1-dependent mechanisms in Parkinson's disease.
Lactylation of Mitochondrial Adenosine Triphosphate Synthase Subunit Alpha Regulates Vascular Remodeling and Progression of Aortic Dissection.
Astaxanthin alleviates oxidative stress and skeletal muscle damage by promoting mitochondrial biogenesis.
HIGD1A Alleviates Oxidative Stress Related Ovarian Hypofunction by Enhancing Granulosa Cell Functions via NF-κB/SOD2 Signaling Pathway.
A two-strata energy flux system driven by a stress hormone prioritizes cardiac energetics.
Iron overload exaggerates renal ischemia-reperfusion injury by promoting tubular cuproptosis via interrupting function of LIAS.
Cannabidiol alleviates methamphetamine addiction via targeting ATP5A1 and modulating the ATP-ADO-A1R signaling pathway.
Development of Two In Vitro ND1-LHON Models for Evaluating Gene Therapy Efficacy.
Iron supplementation protects against renal ischemia-reperfusion injury by enhancing mitochondrial respiratory complex assembly.
Galectin-3 directs mitophagy in response to Parkin-/proteasome-dependent rupture of mitochondrial outer membrane.
Cell-type-specific dysregulation of mitochondrial calcium signaling in Alzheimer's disease.
CHCHD2 mutant mice link mitochondrial deficits to PD pathophysiology.
Mitochondrial NADPH fuels mitochondrial fatty acid synthesis and lipoylation to power oxidative metabolism.
PPDPF preserves integrity of proximal tubule by modulating NMNAT activity in chronic kidney diseases.
Tetraspanin7 in adipose tissue remodeling and its impact on metabolic health.
Apaf-1 is an evolutionarily conserved DNA sensor that switches the cell fate between apoptosis and inflammation.
Endothelial FUNDC1 Deficiency Drives Pulmonary Hypertension.
Analysis of the Protective Mechanism of PGC-1α/NRF1/2/TFAM Pathway in Cortical Neuron Injury Induced by Oxidative Stress.
Defective vascular smooth muscle cell tafazzin impairs mitochondrial function and promotes atherosclerosis in preclinical models.
Dimethyl fumarate improves non-alcoholic fatty liver disease by regulating SIRT1 signal to inhibit MAMs over-enrichment.
Cellular ATP demand creates metabolically distinct subpopulations of mitochondria.
Emodin Blocks mPTP Opening and Improves LPS-Induced HMEC-1 Cell Injury by Upregulation of ATP5A1.
Mulberry leaf flavonoids activate BAT and induce browning of WAT to improve type 2 diabetes via regulating the AMPK/SIRT1/PGC-1α signaling pathway.
Zhen Wu decoction represses renal fibrosis by invigorating tubular NRF2 and TFAM to fuel mitochondrial bioenergetics.
The non-redundant functions of PIWI family proteins in gametogenesis in golden hamsters.
Fluoride impairs mitochondrial translation by targeting miR-221-3p/c-Fos/RMND1 axis contributing to neurodevelopment defects.
Inulin-type fructans change the gut microbiota and prevent the development of diabetic nephropathy.
CHCHD10 Modulates Thermogenesis of Adipocytes by Regulating Lipolysis.
Berberine mitigates hepatic insulin resistance by enhancing mitochondrial architecture via the SIRT1/Opa1 signalling pathway.
Geometric Constraints Regulate Energy Metabolism and Cellular Contractility in Vascular Smooth Muscle Cells by Coordinating Mitochondrial DNA Methylation.
Rutin-activated adipose tissue thermogenesis is correlated with increased intestinal short-chain fatty acid levels.
PDGF signaling inhibits mitophagy in glioblastoma stem cells through N(6)-methyladenosine.
Genome-wide CRISPRi screening identifies OCIAD1 as a prohibitin client and regulatory determinant of mitochondrial Complex III assembly in human cells.
AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1.
Affinity-based protein profiling to reveal targets of puerarin involved in its protective effect on cardiomyocytes.
Assessment of SENP3-interacting proteins in hepatocytes treated with diethylnitrosamine by BioID assay.
Quantitative Mitochondrial Proteomics Reveals ANXA7 as a Crucial Factor in Mitophagy.
A cross-talk between epithelium and endothelium mediates human alveolar-capillary injury during SARS-CoV-2 infection.
AKT-mediated phosphorylation of ATG4B impairs mitochondrial activity and enhances the Warburg effect in hepatocellular carcinoma cells.
Region of Interest analysis using mass spectrometry imaging of mitochondrial and sarcomeric proteins in acute cardiac infarction tissue.
Succinate induces aberrant mitochondrial fission in cardiomyocytes through GPR91 signaling.
Succinate-induced neuronal mitochondrial fission and hexokinase II malfunction in ischemic stroke: Therapeutical effects of kaempferol.
Ginkgolide K attenuates neuronal injury after ischemic stroke by inhibiting mitochondrial fission and GSK-3β-dependent increases in mitochondrial membrane permeability.
Quantitative proteomic study of myocardial mitochondria in urea transporter B knockout mice.
Mao Y, Lin S, Wu M, Ma H, Ji J, Zhou H
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158020
Phytomedicine : international journal of phytotherapy and phytopharmacology 2026 May;154:158020
UFMylation of Pyruvate Dehydrogenase Regulates Mitochondrial Metabolism.
Nguyen PT, Wu Z, Kim D, Ogu T, Yin S, Sondhi V, Cai F, Tippetts TS, Jen A, Shishkova E, Cai L, Dumesnil D, Cervantes M, Chen H, Mishra P, Coon JJ, Hoxhaj G, Ni M, DeBerardinis RJ
bioRxiv : the preprint server for biology 2026 Mar 18;
bioRxiv : the preprint server for biology 2026 Mar 18;
Txnrd2 loss in skeletal muscle causes muscle atrophy and drives leanness and obesity resistance.
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Redox biology 2026 Jun;93:104165
UQCRC1 deficiency impairs mitophagy via PINK1-dependent mechanisms in Parkinson's disease.
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Lactylation of Mitochondrial Adenosine Triphosphate Synthase Subunit Alpha Regulates Vascular Remodeling and Progression of Aortic Dissection.
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Frontiers in veterinary science 2025;12:1577408
HIGD1A Alleviates Oxidative Stress Related Ovarian Hypofunction by Enhancing Granulosa Cell Functions via NF-κB/SOD2 Signaling Pathway.
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Redox biology 2025 Oct;86:103795
Cannabidiol alleviates methamphetamine addiction via targeting ATP5A1 and modulating the ATP-ADO-A1R signaling pathway.
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Cell-type-specific dysregulation of mitochondrial calcium signaling in Alzheimer's disease.
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Nature cell biology 2025 May;27(5):790-800
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Tetraspanin7 in adipose tissue remodeling and its impact on metabolic health.
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Apaf-1 is an evolutionarily conserved DNA sensor that switches the cell fate between apoptosis and inflammation.
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Analysis of the Protective Mechanism of PGC-1α/NRF1/2/TFAM Pathway in Cortical Neuron Injury Induced by Oxidative Stress.
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Defective vascular smooth muscle cell tafazzin impairs mitochondrial function and promotes atherosclerosis in preclinical models.
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Nature communications 2025 Dec 4;16(1):10909
Dimethyl fumarate improves non-alcoholic fatty liver disease by regulating SIRT1 signal to inhibit MAMs over-enrichment.
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European journal of pharmacology 2025 Aug 5;1000:177693
Cellular ATP demand creates metabolically distinct subpopulations of mitochondria.
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Emodin Blocks mPTP Opening and Improves LPS-Induced HMEC-1 Cell Injury by Upregulation of ATP5A1.
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Mulberry leaf flavonoids activate BAT and induce browning of WAT to improve type 2 diabetes via regulating the AMPK/SIRT1/PGC-1α signaling pathway.
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Zhen Wu decoction represses renal fibrosis by invigorating tubular NRF2 and TFAM to fuel mitochondrial bioenergetics.
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Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;108:154495
Phytomedicine : international journal of phytotherapy and phytopharmacology 2023 Jan;108:154495
The non-redundant functions of PIWI family proteins in gametogenesis in golden hamsters.
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Nature communications 2023 Aug 29;14(1):5267
Nature communications 2023 Aug 29;14(1):5267
Fluoride impairs mitochondrial translation by targeting miR-221-3p/c-Fos/RMND1 axis contributing to neurodevelopment defects.
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Inulin-type fructans change the gut microbiota and prevent the development of diabetic nephropathy.
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Pharmacological research 2022 Sep;183:106367
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Diabetes 2022 Sep 1;71(9):1862-1879
Diabetes 2022 Sep 1;71(9):1862-1879
Berberine mitigates hepatic insulin resistance by enhancing mitochondrial architecture via the SIRT1/Opa1 signalling pathway.
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Acta biochimica et biophysica Sinica 2022 Oct 25;54(10):1464-1475
Geometric Constraints Regulate Energy Metabolism and Cellular Contractility in Vascular Smooth Muscle Cells by Coordinating Mitochondrial DNA Methylation.
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Rutin-activated adipose tissue thermogenesis is correlated with increased intestinal short-chain fatty acid levels.
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eLife 2021 May 26;10
eLife 2021 May 26;10
AIDA directly connects sympathetic innervation to adaptive thermogenesis by UCP1.
Shi M, Huang XY, Ren XY, Wei XY, Ma Y, Lin ZZ, Liu DT, Song L, Zhao TJ, Li G, Yao L, Zhu M, Zhang C, Xie C, Wu Y, Wu HM, Fan LP, Ou J, Zhan YH, Lin SY, Lin SC
Nature cell biology 2021 Mar;23(3):268-277
Nature cell biology 2021 Mar;23(3):268-277
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Acta biochimica et biophysica Sinica 2021 Aug 31;53(9):1237-1246
Acta biochimica et biophysica Sinica 2021 Aug 31;53(9):1237-1246
Quantitative Mitochondrial Proteomics Reveals ANXA7 as a Crucial Factor in Mitophagy.
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Journal of proteome research 2020 Mar 6;19(3):1275-1284
Journal of proteome research 2020 Mar 6;19(3):1275-1284
A cross-talk between epithelium and endothelium mediates human alveolar-capillary injury during SARS-CoV-2 infection.
Wang P, Luo R, Zhang M, Wang Y, Song T, Tao T, Li Z, Jin L, Zheng H, Chen W, Zhao M, Zheng Y, Qin J
Cell death & disease 2020 Dec 8;11(12):1042
Cell death & disease 2020 Dec 8;11(12):1042
AKT-mediated phosphorylation of ATG4B impairs mitochondrial activity and enhances the Warburg effect in hepatocellular carcinoma cells.
Ni Z, He J, Wu Y, Hu C, Dai X, Yan X, Li B, Li X, Xiong H, Li Y, Li S, Xu L, Li Y, Lian J, He F
Autophagy 2018;14(4):685-701
Autophagy 2018;14(4):685-701
Region of Interest analysis using mass spectrometry imaging of mitochondrial and sarcomeric proteins in acute cardiac infarction tissue.
Yajima Y, Hiratsuka T, Kakimoto Y, Ogawa S, Shima K, Yamazaki Y, Yoshikawa K, Tamaki K, Tsuruyama T
Scientific reports 2018 May 10;8(1):7493
Scientific reports 2018 May 10;8(1):7493
Succinate induces aberrant mitochondrial fission in cardiomyocytes through GPR91 signaling.
Lu YT, Li LZ, Yang YL, Yin X, Liu Q, Zhang L, Liu K, Liu B, Li J, Qi LW
Cell death & disease 2018 Jun 4;9(6):672
Cell death & disease 2018 Jun 4;9(6):672
Succinate-induced neuronal mitochondrial fission and hexokinase II malfunction in ischemic stroke: Therapeutical effects of kaempferol.
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Biochimica et biophysica acta. Molecular basis of disease 2017 Sep;1863(9):2307-2318
Biochimica et biophysica acta. Molecular basis of disease 2017 Sep;1863(9):2307-2318
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Oncotarget 2017 Jul 4;8(27):44682-44693
Oncotarget 2017 Jul 4;8(27):44682-44693
Quantitative proteomic study of myocardial mitochondria in urea transporter B knockout mice.
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Proteomics 2014 Sep;14(17-18):2072-83
Proteomics 2014 Sep;14(17-18):2072-83
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Western blot analysis of ATP5A1 in various tissues and cell lines using Proteintech antibody 66037-1-Ig at the dilution of 1:1000.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunofluorescent analysis of Hela cells, using ATP5A1 antibody 66037-1-lg at 1:50 dilution and Rhodamine-labeled goat anti-mouse IgG (red). Blue pseudocolor = DAPI (fluorescent DNA dye).
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human heart using 66037-1-Ig(ATP5A1 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image

- Experimental details
- Immunohistochemical of paraffin-embedded human heart using 66037-1-Ig(ATP5A1 antibody) at dilution of 1:50 (under 40x lens)
- Sample type
- tissue