Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 22792-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- SPAST antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated SPAST antibody (Cat. #22792-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat and has been validated for the following applications: WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Spastin regulates anaphase chromosome separation distance and microtubule-containing nuclear tunnels.
The enhanced association between mutant CHMP2B and spastin is a novel pathological link between frontotemporal dementia and hereditary spastic paraplegias.
Resolving ESCRT-III Spirals at the Intercellular Bridge of Dividing Cells Using 3D STORM.
Regulation of the blood-testis barrier by a local axis in the testis: role of laminin α2 in the basement membrane.
Kelley ME, Carlini L, Kornakov N, Aher A, Khodjakov A, Kapoor TM
Molecular biology of the cell 2024 Apr 1;35(4):ar48
Molecular biology of the cell 2024 Apr 1;35(4):ar48
The enhanced association between mutant CHMP2B and spastin is a novel pathological link between frontotemporal dementia and hereditary spastic paraplegias.
Chen Y, Krishnan G, Parsi S, Pons M, Nikolaki V, Cao L, Xu Z, Gao FB
Acta neuropathologica communications 2022 Nov 22;10(1):169
Acta neuropathologica communications 2022 Nov 22;10(1):169
Resolving ESCRT-III Spirals at the Intercellular Bridge of Dividing Cells Using 3D STORM.
Goliand I, Adar-Levor S, Segal I, Nachmias D, Dadosh T, Kozlov MM, Elia N
Cell reports 2018 Aug 14;24(7):1756-1764
Cell reports 2018 Aug 14;24(7):1756-1764
Regulation of the blood-testis barrier by a local axis in the testis: role of laminin α2 in the basement membrane.
Gao Y, Mruk D, Chen H, Lui WY, Lee WM, Cheng CY
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Feb;31(2):584-597
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2017 Feb;31(2):584-597
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Supportive validation
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- Proteintech Group (provider)
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- Experimental details
- The SPAST antibody from Proteintech is a rabbit polyclonal antibody to a fusion protein of human SPAST. This antibody recognizes human, mouse, rat antigen. The SPAST antibody has been validated for the following applications: ELISA, WB analysis.