ATP12A

The protein encoded by this gene belongs to the family of P-type cation transport ATPases. This gene encodes a catalytic subunit of the ouabain-sensitive H+/K+ -ATPase that catalyzes the hydrolysis of ATP coupled with the exchange of H(+) and K(+) ions across the plasma membrane. It is also responsible for potassium absorption in various tissues. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2010]

Description

ATPase, H+/K+ transporting, nongastric, alpha polypeptide

Protein family

Enzymes, Mapped to UniProt SWISS-PROT, Plasma proteins, Predicted membrane proteins, Protein evidence (Ezkurdia et al 2014), Protein evidence (Kim et al 2014)

Chromosome

13:q12.12 (24680411 - 24712493)

Ensembl ID

ENSG00000075673  (ver. 84.38)

Orthologs

Mouse Atp12a: ENSMUSG00000022229

UniProt

P54707

neXtProt

NX_P54707

Human splice variants
Mouse splice variants