Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- RP1099 - Provider product page
- Provider
- Boster Biological Technology
- Product name
- Anti-GTPase HRAS Antibody
- Antibody type
- Polyclonal
- Description
- Polyclonal antibody for VH RAS/HRAS detection. Host: Rabbit.Size: 100μg/vial. Tested applications: WB. Reactive species: Human. VH RAS/HRAS information: Molecular Weight: 21298 MW; Subcellular Localization: Cell membrane. Cell membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus. Golgi apparatus membrane; Lipid-anchor. The active GTP-bound form is localized most strongly to membranes than the inactive GDP-bound form (By similarity). Shuttles between the plasma membrane and the Golgi apparatus; Tissue Specificity: Widely expressed.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Vial size
- 100μg/vial
- Concentration
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
- Storage
- At -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquoted and stored frozen at -20°C for a longer time. Avoid repeated freezing and thawing.
- Handling
- Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Submitted references The Ras signaling pathway mediates cetuximab resistance in nasopharyngeal carcinoma.
Development of cetuximab-resistant human nasopharyngeal carcinoma cell lines and mechanisms of drug resistance.
Integrin beta4 mAb inhibited apoptosis induced by deprivation of growth factors in vascular endothelial cells.
Zuo Q, Shi M, Chen J, Liao W
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2011 Jun;65(3):168-74
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2011 Jun;65(3):168-74
Development of cetuximab-resistant human nasopharyngeal carcinoma cell lines and mechanisms of drug resistance.
Zuo Q, Shi M, Li L, Chen J, Luo R
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2010 Oct;64(8):550-8
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2010 Oct;64(8):550-8
Integrin beta4 mAb inhibited apoptosis induced by deprivation of growth factors in vascular endothelial cells.
Zhao KW, Zhao QT, Zhang SL, Miao JY
Acta pharmacologica Sinica 2004 Jun;25(6):733-7
Acta pharmacologica Sinica 2004 Jun;25(6):733-7
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Supportive validation
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- Boster Biological Technology (provider)
- Main image
- Experimental details
- Anti-GTPase HRAS antibody, RP1099, Western blottingAll lanes: Anti GTPase HRAS (RP1099) at 0.5ug/mlLane 1: Rat Brain Tissue Lysate at 50ugLane 2: Mouse Brain Tissue Lysate at 50ugLane 3: HEPA Whole Cell Lysate at 40ugPredicted bind size: 21KDObserved bind size: 21KD
- Additional image