Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- 25339-1-AP - Provider product page
- Provider
- Proteintech Group
- Product name
- ABCA7 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated ABCA7 antibody (Cat. #25339-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat, mouse and has been validated for the following applications: IHC, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references ABCA7 deficiency causes neuronal dysregulation by altering mitochondrial lipid metabolism.
ABCA7 Downregulation Modifies Cellular Cholesterol Homeostasis and Decreases Amyloid-β Peptide Efflux in an in vitro Model of the Blood-Brain Barrier.
ATP-binding cassette transporter A7 accelerates epithelial-to-mesenchymal transition in ovarian cancer cells by upregulating the transforming growth factor-β signaling pathway.
Kawatani K, Holm ML, Starling SC, Martens YA, Zhao J, Lu W, Ren Y, Li Z, Jiang P, Jiang Y, Baker SK, Wang N, Roy B, Parsons TM, Perkerson RB 3rd, Bao H, Han X, Bu G, Kanekiyo T
Molecular psychiatry 2024 Mar;29(3):809-819
Molecular psychiatry 2024 Mar;29(3):809-819
ABCA7 Downregulation Modifies Cellular Cholesterol Homeostasis and Decreases Amyloid-β Peptide Efflux in an in vitro Model of the Blood-Brain Barrier.
Lamartinière Y, Boucau MC, Dehouck L, Krohn M, Pahnke J, Candela P, Gosselet F, Fenart L
Journal of Alzheimer's disease : JAD 2018;64(4):1195-1211
Journal of Alzheimer's disease : JAD 2018;64(4):1195-1211
ATP-binding cassette transporter A7 accelerates epithelial-to-mesenchymal transition in ovarian cancer cells by upregulating the transforming growth factor-β signaling pathway.
Liu X, Li Q, Zhou J, Zhang S
Oncology letters 2018 Nov;16(5):5868-5874
Oncology letters 2018 Nov;16(5):5868-5874
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Supportive validation
- Submitted by
- Proteintech Group (provider)
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- Experimental details
- The ABCA7 antibody from Proteintech is a rabbit polyclonal antibody to a peptide of human ABCA7. This antibody recognizes human, mouse antigen. The ABCA7 antibody has been validated for the following applications: ELISA, WB analysis.