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- References [24]
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- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- 13095-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#13095-1-AP, RRID:AB_2090576
- Product name
- DCT antibody
- Antibody type
- Polyclonal
- Description
- DCT antibody (Cat. #13095-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse, rat, monkey and has been validated for the following applications: IHC, IP, WB,ELISA.
- Reactivity
- Human, Mouse, Rat, Simian
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references A Novel FGF2-Targeted Inhibitor (N-trans-feruloyloctopamine) Suppresses UVB-Induced Skin Damage and Hyperpigmentation.
3, 7-dihydroxy-2, 4-dimethoxyphenanthrene protects against UVB-induced skin hyperpigmentation via antioxidant and anti-melanogenic mechanisms.
Comprehensive single-cell transcriptomic reveals different destinies of melanocytes and dynamic changes of immune microenvironment in a psychological stress-induced leukoderma and leukotrichia mouse model.
Epigallocatechin-3-Gallate and Glabridin Synergistically Inhibited Melanogenesis by Molecular Interaction and the MicroRNA-Microphthalmia-Related Transcription Factor Pathway.
Oxyresveratrol suppressed melanogenesis, dendrite formation, and melanosome transport in melanocytes via regulation of the MC1R/cAMP/MITF pathway.
Palmitoyl copper peptide and acetyl tyrosine complex enhances melanin production in both A375 and B16 cell lines.
Hair follicle-targeted delivery for hair recoloration using scalp-curvature-conforming microneedles based on sodium alginate and polyvinylpyrrolidone.
Components analysis of San-Bai decoction, and its pharmacodynamics and mechanism on preventing and treating melasma.
Fast freezing inhibits melanin synthesis of melanocytes by modulating the Wnt/β-catenin signalling pathway.
Preparation of paeoniflorin-glycyrrhizic acid complex transethosome gel and its preventive and therapeutic effects on melasma.
Anti-Melanogenic Effects of Takifugu flavidus Muscle Hydrolysate in B16F10 Melanoma Cells and Zebrafish.
Silver Carp (Hypophthalmichthys molitrix) Scale Collagen Peptides-1 (SCPs1) Inhibit Melanogenesis through Downregulation of the cAMP-CREB Signaling Pathway.
Kaempferol promotes melanogenesis and reduces oxidative stress in PIG1 normal human skin melanocytes.
Elimination of senescent cells inhibits epithelial-mesenchymal transition of retinal pigment epithelial cells.
Anti-Melanogenic Mechanism of Tetrahydrocurcumin and Enhancing Its Topical Delivery Efficacy Using a Lecithin-Based Nanoemulsion.
A biomimetic antitumor nanovaccine based on biocompatible calcium pyrophosphate and tumor cell membrane antigens.
Stem cell spreading dynamics intrinsically differentiate acral melanomas from nevi.
Neuropsin (OPN5) Mediates Local Light-Dependent Induction of Circadian Clock Genes and Circadian Photoentrainment in Exposed Murine Skin.
Loss of tumorigenic potential upon transdifferentiation from keratinocytic into melanocytic lineage.
Immunotargeting and eradication of orthotopic melanoma using a chemokine-enhanced DNA vaccine.
Inhibition of melanogenesis by gallic acid: possible involvement of the PI3K/Akt, MEK/ERK and Wnt/β-catenin signaling pathways in B16F10 cells.
miR-137 inhibits the invasion of melanoma cells through downregulation of multiple oncogenic target genes.
MiR-101 inhibits melanoma cell invasion and proliferation by targeting MITF and EZH2.
Transcriptome analysis and molecular signature of human retinal pigment epithelium.
Li B, Jin W, Liu B, Yang J, Wu S, He M, Jiang Z, Wang Z, Huang L, Li X, Cao K, Duan L, Wang K, Lai C, Gao Y, Cai H
Advanced healthcare materials 2026 Mar;15(9):e02250
Advanced healthcare materials 2026 Mar;15(9):e02250
3, 7-dihydroxy-2, 4-dimethoxyphenanthrene protects against UVB-induced skin hyperpigmentation via antioxidant and anti-melanogenic mechanisms.
Li M, Li D, Zhang Y, Wang J, Zhang Z, Wang W, Chen S, Lyu L, Liu W
Journal of photochemistry and photobiology. B, Biology 2025 Nov;272:113277
Journal of photochemistry and photobiology. B, Biology 2025 Nov;272:113277
Comprehensive single-cell transcriptomic reveals different destinies of melanocytes and dynamic changes of immune microenvironment in a psychological stress-induced leukoderma and leukotrichia mouse model.
Cao X, Yu Y, Yao H, Zheng Y, Lu J, Feng Y, Pei T, Li Z, Lu M, Lu Y
Molecular medicine (Cambridge, Mass.) 2025 May 14;31(1):186
Molecular medicine (Cambridge, Mass.) 2025 May 14;31(1):186
Epigallocatechin-3-Gallate and Glabridin Synergistically Inhibited Melanogenesis by Molecular Interaction and the MicroRNA-Microphthalmia-Related Transcription Factor Pathway.
Song J, Chen Z, Li T, Xu W, Feng G, Ge J
Journal of medicinal food 2025 Jun;28(6):553-567
Journal of medicinal food 2025 Jun;28(6):553-567
Oxyresveratrol suppressed melanogenesis, dendrite formation, and melanosome transport in melanocytes via regulation of the MC1R/cAMP/MITF pathway.
Zhang J, Liu S, Guo W, Huang Y, Li N
Scientific reports 2025 Jul 1;15(1):20400
Scientific reports 2025 Jul 1;15(1):20400
Palmitoyl copper peptide and acetyl tyrosine complex enhances melanin production in both A375 and B16 cell lines.
Hong M, Gui Y, Xu J, Zhao X, Jiang C, Zhao J, Xin X, Liu D, Tang X, Tang R, An F
Biochemical and biophysical research communications 2025 Jan;742:151060
Biochemical and biophysical research communications 2025 Jan;742:151060
Hair follicle-targeted delivery for hair recoloration using scalp-curvature-conforming microneedles based on sodium alginate and polyvinylpyrrolidone.
Hu J, Xu Y, Ma X, Hu W, Zhang Y, Ye Y, Yang S, Lin H, Sheng X, Wu J, Zhang T, Gao J
International journal of biological macromolecules 2024 Sep 24;280(Pt 3):135917
International journal of biological macromolecules 2024 Sep 24;280(Pt 3):135917
Components analysis of San-Bai decoction, and its pharmacodynamics and mechanism on preventing and treating melasma.
Xiao Y, Tao W, Shan X, Li D, Tao W, Qian H, Zhao Y, Zhang C
Journal of ethnopharmacology 2024 Oct 5;332:118388
Journal of ethnopharmacology 2024 Oct 5;332:118388
Fast freezing inhibits melanin synthesis of melanocytes by modulating the Wnt/β-catenin signalling pathway.
Wu S, Yuan X, Tang Z, Zang K, Wang C, Li Z, Li H, Ye X, Dang Y
Experimental dermatology 2024 May;33(5):e15101
Experimental dermatology 2024 May;33(5):e15101
Preparation of paeoniflorin-glycyrrhizic acid complex transethosome gel and its preventive and therapeutic effects on melasma.
Xiao Y, Zhou L, Tao W, Yang X, Li J, Wang R, Zhao Y, Peng C, Zhang C
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2024 Jan 1;192:106664
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2024 Jan 1;192:106664
Anti-Melanogenic Effects of Takifugu flavidus Muscle Hydrolysate in B16F10 Melanoma Cells and Zebrafish.
Hu J, Chen B, Qu S, Liu S, Yang X, Qiao K, Su Y, Liu Z, Chen X, Liu Z, Wang Q
Marine drugs 2024 Apr 29;22(5)
Marine drugs 2024 Apr 29;22(5)
Silver Carp (Hypophthalmichthys molitrix) Scale Collagen Peptides-1 (SCPs1) Inhibit Melanogenesis through Downregulation of the cAMP-CREB Signaling Pathway.
Li HL, Li MJ, Xiong GQ, Cai J, Liao T, Zu XY
Nutrients 2023 May 24;15(11)
Nutrients 2023 May 24;15(11)
Kaempferol promotes melanogenesis and reduces oxidative stress in PIG1 normal human skin melanocytes.
Xie Y, Mei X, Shi W
Journal of cellular and molecular medicine 2023 Apr;27(7):982-990
Journal of cellular and molecular medicine 2023 Apr;27(7):982-990
Elimination of senescent cells inhibits epithelial-mesenchymal transition of retinal pigment epithelial cells.
Gao F, Wang L, Wu B, Ou Q, Tian H, Xu J, Jin C, Zhang J, Wang J, Lu L, Xu GT
Experimental eye research 2022 Oct;223:109207
Experimental eye research 2022 Oct;223:109207
Anti-Melanogenic Mechanism of Tetrahydrocurcumin and Enhancing Its Topical Delivery Efficacy Using a Lecithin-Based Nanoemulsion.
Tang X, Dong Q, Li J, Li F, Michniak-Kohn BB, Zhao D, Ho CT, Huang Q
Pharmaceutics 2021 Jul 31;13(8)
Pharmaceutics 2021 Jul 31;13(8)
A biomimetic antitumor nanovaccine based on biocompatible calcium pyrophosphate and tumor cell membrane antigens.
Li M, Qin M, Song G, Deng H, Wang D, Wang X, Dai W, He B, Zhang H, Zhang Q
Asian journal of pharmaceutical sciences 2021 Jan;16(1):97-109
Asian journal of pharmaceutical sciences 2021 Jan;16(1):97-109
Stem cell spreading dynamics intrinsically differentiate acral melanomas from nevi.
Eshiba S, Namiki T, Mohri Y, Aida T, Serizawa N, Shibata T, Morinaga H, Nanba D, Hiraoka Y, Tanaka K, Miura K, Tanaka M, Uhara H, Yokozeki H, Saida T, Nishimura EK
Cell reports 2021 Aug 3;36(5):109492
Cell reports 2021 Aug 3;36(5):109492
Neuropsin (OPN5) Mediates Local Light-Dependent Induction of Circadian Clock Genes and Circadian Photoentrainment in Exposed Murine Skin.
Buhr ED, Vemaraju S, Diaz N, Lang RA, Van Gelder RN
Current biology : CB 2019 Oct 21;29(20):3478-3487.e4
Current biology : CB 2019 Oct 21;29(20):3478-3487.e4
Loss of tumorigenic potential upon transdifferentiation from keratinocytic into melanocytic lineage.
Fehrenbach S, Novak D, Bernhardt M, Larribere L, Boukamp P, Umansky V, Utikal J
Scientific reports 2016 Jul 8;6:28891
Scientific reports 2016 Jul 8;6:28891
Immunotargeting and eradication of orthotopic melanoma using a chemokine-enhanced DNA vaccine.
Igoucheva O, Grazzini M, Pidich A, Kemp DM, Larijani M, Farber M, Lorton J, Rodeck U, Alexeev V
Gene therapy 2013 Sep;20(9):939-48
Gene therapy 2013 Sep;20(9):939-48
Inhibition of melanogenesis by gallic acid: possible involvement of the PI3K/Akt, MEK/ERK and Wnt/β-catenin signaling pathways in B16F10 cells.
Su TR, Lin JJ, Tsai CC, Huang TK, Yang ZY, Wu MO, Zheng YQ, Su CC, Wu YJ
International journal of molecular sciences 2013 Oct 14;14(10):20443-58
International journal of molecular sciences 2013 Oct 14;14(10):20443-58
miR-137 inhibits the invasion of melanoma cells through downregulation of multiple oncogenic target genes.
Luo C, Tetteh PW, Merz PR, Dickes E, Abukiwan A, Hotz-Wagenblatt A, Holland-Cunz S, Sinnberg T, Schittek B, Schadendorf D, Diederichs S, Eichmüller SB
The Journal of investigative dermatology 2013 Mar;133(3):768-775
The Journal of investigative dermatology 2013 Mar;133(3):768-775
MiR-101 inhibits melanoma cell invasion and proliferation by targeting MITF and EZH2.
Luo C, Merz PR, Chen Y, Dickes E, Pscherer A, Schadendorf D, Eichmüller SB
Cancer letters 2013 Dec 1;341(2):240-7
Cancer letters 2013 Dec 1;341(2):240-7
Transcriptome analysis and molecular signature of human retinal pigment epithelium.
Strunnikova NV, Maminishkis A, Barb JJ, Wang F, Zhi C, Sergeev Y, Chen W, Edwards AO, Stambolian D, Abecasis G, Swaroop A, Munson PJ, Miller SS
Human molecular genetics 2010 Jun 15;19(12):2468-86
Human molecular genetics 2010 Jun 15;19(12):2468-86
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- A375 cells were subjected to SDS PAGE followed by western blot with 13095-1-AP(DCT antibody) at dilution of 1:500
- Sample type
- cell line
Supportive validation
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The DCT antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human DCT. This antibody recognizes human,mouse,rat, monkey antigen. The DCT antibody has been validated for the following applications: ELISA, WB, IHC analysis.
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human skin using 13095-1-AP(DCT antibody) at dilution of 1:100 (under 10x lens)
- Sample type
- tissue
