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antibody from antibodies-online
Targeting: CENPJ
BM032, CPAP, LAP, LIP1, MCPH6, Sas-4, SASS4, SCKL4
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- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Western blot [1]
- Immunohistochemistry [2]
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- Product number
- ABIN394394 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Centromere Protein J (CENPJ) (AA 979-1089) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 979-1089
- Isotype
- IgG
- Antibody clone number
- 5D5
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Novel CENPJ mutation causes Seckel syndrome.
PLK2 phosphorylation is critical for CPAP function in procentriole formation during the centrosome cycle.
Sex-dependent association of common variants of microcephaly genes with brain structure.
Dimerization of CPAP orchestrates centrosome cohesion plasticity.
CPAP is a cell-cycle regulated protein that controls centriole length.
Al-Dosari MS, Shaheen R, Colak D, Alkuraya FS
Journal of medical genetics 2010 Jun;47(6):411-4
Journal of medical genetics 2010 Jun;47(6):411-4
PLK2 phosphorylation is critical for CPAP function in procentriole formation during the centrosome cycle.
Chang J, Cizmecioglu O, Hoffmann I, Rhee K
The EMBO journal 2010 Jul 21;29(14):2395-406
The EMBO journal 2010 Jul 21;29(14):2395-406
Sex-dependent association of common variants of microcephaly genes with brain structure.
Rimol LM, Agartz I, Djurovic S, Brown AA, Roddey JC, Kähler AK, Mattingsdal M, Athanasiu L, Joyner AH, Schork NJ, Halgren E, Sundet K, Melle I, Dale AM, Andreassen OA, Alzheimer's Disease Neuroimaging Initiative.
Proceedings of the National Academy of Sciences of the United States of America 2010 Jan 5;107(1):384-8
Proceedings of the National Academy of Sciences of the United States of America 2010 Jan 5;107(1):384-8
Dimerization of CPAP orchestrates centrosome cohesion plasticity.
Zhao L, Jin C, Chu Y, Varghese C, Hua S, Yan F, Miao Y, Liu J, Mann D, Ding X, Zhang J, Wang Z, Dou Z, Yao X
The Journal of biological chemistry 2010 Jan 22;285(4):2488-97
The Journal of biological chemistry 2010 Jan 22;285(4):2488-97
CPAP is a cell-cycle regulated protein that controls centriole length.
Tang CJ, Fu RH, Wu KS, Hsu WB, Tang TK
Nature cell biology 2009 Jul;11(7):825-31
Nature cell biology 2009 Jul;11(7):825-31
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Supportive validation
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
- Submitted by
- antibodies-online (provider)
- Main image
- Experimental details
- IHC
