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- Antigen structure
- References [15]
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- Western blot [1]
- Immunohistochemistry [1]
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- Product number
- 10448-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10448-1-AP, RRID:AB_2282772
- Product name
- NOP2 antibody
- Antibody type
- Polyclonal
- Description
- NOP2 antibody (Cat. #10448-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat, mouse and has been validated for the following applications: IF, IHC, WB,ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Aberrant NSUN1 activity connects m(5)C-RNA modification to TDP-43 neurotoxicity in ALS/FTD.
Molecular recording of cellular protein kinase activity with chemical labeling.
NOP2-Mediated m5C Methylation Modification of LMNB2 mRNA Facilitates Colorectal Cancer Progression.
NSUN2 promotes colorectal cancer progression by stabilizing PHGDH mRNA to promote serine metabolism reprogramming.
NOP2 facilitates EZH2-mediated epithelial-mesenchymal transition by enhancing EZH2 mRNA stability via m5C methylation in lung cancer progression.
Distinct interactomes of ADAR1 nuclear and cytoplasmic protein isoforms and their responses to interferon induction.
The nucleolar phase of signal recognition particle assembly.
N(4)-acetylcytidine of Nop2 mRNA is required for the transition of morula-to-blastocyst.
ZNF692 organizes a hub specialized in 40S ribosomal subunit maturation enhancing translation in rapidly proliferating cells.
Differential toxicity and localization of arginine-rich C9ORF72 dipeptide repeat proteins depend on de-clustering of positive charges.
Function of m(5)C RNA methyltransferase NOP2 in high-grade serous ovarian cancer.
Targeted Quantitative Profiling of Epitranscriptomic Reader, Writer, and Eraser Proteins Using Stable Isotope-Labeled Peptides.
Effect of NOP2 knockdown on colon cancer cell proliferation, migration, and invasion.
DNA damage-induced inhibition of rRNA synthesis by DNA-PK and PARP-1.
RRP1B targets PP1 to mammalian cell nucleoli and is associated with Pre-60S ribosomal subunits.
Parra-Torres M, Dissanayake K, Gray JA, Langlands AJ, Kucuk R, Gierlinski M, Troakes C, King A, McGurk L
Life science alliance 2026 Jan;9(1)
Life science alliance 2026 Jan;9(1)
Molecular recording of cellular protein kinase activity with chemical labeling.
Sun DE, Ng SW, Zheng Y, Xie S, Schwan N, Breuer P, Hoffmann DC, Michel J, Azorin DD, Boonekamp KE, Winkler F, Wick W, Boutros M, Li Y, Johnsson K
Nature chemical biology 2025 Nov;21(11):1818-1827
Nature chemical biology 2025 Nov;21(11):1818-1827
NOP2-Mediated m5C Methylation Modification of LMNB2 mRNA Facilitates Colorectal Cancer Progression.
Bi J, Huang Y, Hu W, Liu Y
Cancer medicine 2025 May;14(10):e70970
Cancer medicine 2025 May;14(10):e70970
NSUN2 promotes colorectal cancer progression by stabilizing PHGDH mRNA to promote serine metabolism reprogramming.
Li H, Gong T, Zhao Y, Luo Y, Tang S, Wang T, Lin H, Zhong M
Cancer & metabolism 2025 Aug 14;13(1):37
Cancer & metabolism 2025 Aug 14;13(1):37
NOP2 facilitates EZH2-mediated epithelial-mesenchymal transition by enhancing EZH2 mRNA stability via m5C methylation in lung cancer progression.
Yang Y, Fan H, Liu H, Lou X, Xiao N, Zhang C, Chen H, Chen S, Gu H, Liu H, Wan J
Cell death & disease 2024 Jul 16;15(7):506
Cell death & disease 2024 Jul 16;15(7):506
Distinct interactomes of ADAR1 nuclear and cytoplasmic protein isoforms and their responses to interferon induction.
Vukić D, Cherian A, Keskitalo S, Bong YT, Marônek M, Yadav L, Keegan LP, Varjosalo M, O'Connell MA
Nucleic acids research 2024 Dec 11;52(22):14184-14204
Nucleic acids research 2024 Dec 11;52(22):14184-14204
The nucleolar phase of signal recognition particle assembly.
Issa A, Schlotter F, Flayac J, Chen J, Wacheul L, Philippe M, Sardini L, Mostefa L, Vandermoere F, Bertrand E, Verheggen C, Lafontaine DL, Massenet S
Life science alliance 2024 Aug;7(8)
Life science alliance 2024 Aug;7(8)
N(4)-acetylcytidine of Nop2 mRNA is required for the transition of morula-to-blastocyst.
Wang M, Cheng R, He H, Han Z, Zhang Y, Wu Q
Cellular and molecular life sciences : CMLS 2023 Sep 28;80(10):307
Cellular and molecular life sciences : CMLS 2023 Sep 28;80(10):307
ZNF692 organizes a hub specialized in 40S ribosomal subunit maturation enhancing translation in rapidly proliferating cells.
Lafita-Navarro MC, Hao YH, Jiang C, Jang S, Chang TC, Brown IN, Venkateswaran N, Maurais E, Stachera W, Zhang Y, Mundy D, Han J, Tran VM, Mettlen M, Xu L, Woodruff JB, Grishin NV, Kinch L, Mendell JT, Buszczak M, Conacci-Sorrell M
Cell reports 2023 Oct 31;42(10):113280
Cell reports 2023 Oct 31;42(10):113280
Differential toxicity and localization of arginine-rich C9ORF72 dipeptide repeat proteins depend on de-clustering of positive charges.
Miyagi T, Ueda K, Sugimoto M, Yagi T, Ito D, Yamazaki R, Narumi S, Hayamizu Y, Uji-I H, Kuroda M, Kanekura K
iScience 2023 Jun 16;26(6):106957
iScience 2023 Jun 16;26(6):106957
Function of m(5)C RNA methyltransferase NOP2 in high-grade serous ovarian cancer.
Yang S, Zhou D, Zhang C, Xiang J, Xi X
Cancer biology & therapy 2023 Dec 31;24(1):2263921
Cancer biology & therapy 2023 Dec 31;24(1):2263921
Targeted Quantitative Profiling of Epitranscriptomic Reader, Writer, and Eraser Proteins Using Stable Isotope-Labeled Peptides.
Qi TF, Liu X, Tang F, Yin J, Yu K, Wang Y
Analytical chemistry 2022 Sep 20;94(37):12559-12564
Analytical chemistry 2022 Sep 20;94(37):12559-12564
Effect of NOP2 knockdown on colon cancer cell proliferation, migration, and invasion.
Bi J, Huang Y, Liu Y
Translational cancer research 2019 Oct;8(6):2274-2283
Translational cancer research 2019 Oct;8(6):2274-2283
DNA damage-induced inhibition of rRNA synthesis by DNA-PK and PARP-1.
Calkins AS, Iglehart JD, Lazaro JB
Nucleic acids research 2013 Aug;41(15):7378-86
Nucleic acids research 2013 Aug;41(15):7378-86
RRP1B targets PP1 to mammalian cell nucleoli and is associated with Pre-60S ribosomal subunits.
Chamousset D, De Wever V, Moorhead GB, Chen Y, Boisvert FM, Lamond AI, Trinkle-Mulcahy L
Molecular biology of the cell 2010 Dec;21(23):4212-26
Molecular biology of the cell 2010 Dec;21(23):4212-26
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- HEK-293 cells were subjected to SDS PAGE followed by western blot with 10448-1-AP(NOP2 antibody) at dilution of 1:3000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The NOP2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human NOP2. This antibody recognizes human antigen. The NOP2 antibody has been validated for the following applications: ELISA, WB, IHC analysis.
